CAS: 82337-46-0; 12(R)-Hete

上下游产品

all cis 5,8,11,14-eicosatetraenoic acid (R)-methyl (5Z,8Z,10Z,14Z)-12-hydroxyeicosa-5,8,10,14-tetraenoate (5Z,8Z,10E)-(R)-12-(tert-Butyl-diphenyl-silanyloxy)-icosa-5,8,10-trien-14-ynoic acid methyl ester Methyl (5Z,8Z,10E,12R,14Z)-12(tert-butyldiphenylsiloxy),5,8,10,14-icosatetraenoate

📜花生四烯酸置于12-Lipoxygenase From Gracliariopsis Lemaneiformis Air体系中,用 乙醇 作为反应溶剂,化学反应 1.33H,反应生成 (5Z,8Z,10E,12R,14Z)-12-羟基-5,8,10,14-二十碳四烯酸
参考文献:12-Lipoxygenase Activity In The Red Marine Alga Gracilariopsis Lemaneiformis
标题:12-Lipoxygenase Activity In The Red Marine Alga Gracilariopsis Lemaneiformis
摘要:
DOI:10.1016/0031-9422(90)85166-D

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-11407837-B2
优先权日:2017-09-11
标 题 :GPCR binding proteins and synthesis thereof
发明人：GLANVILLE JACOB
权利人:TWIST BIOSCIENCE CORP
摘要:Provided herein are methods and compositions relating to G protein-coupled receptor (GPCR) libraries having nucleic acids encoding for a scaffold comprising a GPCR binding domain. Libraries described herein include variegated libraries comprising nucleic acids each encoding for a predetermined variant of at least one predetermined reference nucleic acid sequence. Further described herein are protein libraries generated when the nucleic acid libraries are translated. Further described herein are cell libraries expressing variegated nucleic acid libraries described herein.

专利号:US-4599443-A
优先权日:1981-06-29
标题:Unsaturated eicosanoic acids
发明人：CHAN KA-KONG; HOLLAND GEORGE W; ROSEN PERRY
权利人:HOFFMANN LA ROCHE
摘要:A compound of the formula ##STR1## where R 1 is hydrogen, lower alkyl, alkaline earth metal or alkali metal; or magnesium halide salts thereof, useful as intermediates for unsaturated eicosanoic acids and derivatives thereof which inhibit the synthesis of SRS-A.

专利号:US-4642364-A
优先权日:1981-06-29
标题:Unsaturated eicosanoic acids
发明人：CHAN KA-KONG; HOLLAND GEORGE W; ROSEN PERRY
权利人:HOFFMANN LA ROCHE
摘要:Unsaturated eicosanoic acids and derivatives thereof which inhibit the synthesis of SRS-A are useful for treating and preventing asthma and allergic responses caused by SRS-A as well as useful in inhibiting inflammation.

专利号:US-4500462-A
优先权日:1981-06-29
标题 :Unsaturated eicosanoic acids
发明人：CHAN KA-KONG; HOLLAND GEORGE W; ROSEN PERRY
权利人:HOFFMANN LA ROCHE
摘要:Eicosa-5,8-diynoic acids and 2-fluoro-eicostrien-5-ynoic acid and esters thereof which inhibit the synthesis of SRS-A are useful for treating and preventing asthma and allergic responses caused by SRS-A as well as useful in inhibiting inflammation.

专利号:RU-2037481-C1
优先权日:1989-10-27
标 题:Derivatives of substituted benzoylbenzene-, biphenyl or 2-oxazolealkanoic acid or their pharmacologically acceptable salts, and a method of their synthesis