CAS: 70-70-2; 4'-Hydroxypropiophenone

上下游产品

CAS号79-03-8 丙酰氯 | CAS号108-95-2 苯酚 | CAS号637-27-4 丙酸苯酯 | CAS号121-97-1 4'-甲氧基苯丙酮 | CAS号4495-66-3 4'-苄氧基苯丙酮 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号99-93-4 对羟基苯乙酮 | CAS号108154-92-3 1-[4-(6,7,8,9,1... | CAS号56-53-1 己烯雌酚 | CAS号7507-01-9 3,4-Bis(p-hydro... | CAS号22610-99-7 顺式己烯雌酚 | CAS号35081-45-9 1-[4-(苄氧基)苯基]-2... | CAS号4495-66-3 4'-苄氧基苯丙酮 | CAS号121-97-1 4'-甲氧基苯丙酮 | CAS号501-97-3 对羟基苯丙酸 | CAS号2089-21-6 1-[4-(2-MORPHOL... | CAS号198479-82-2 ethyl 2-[4-[[3-...

4-丙基苯酚置于ferredoxin Reductase,Ferredoxin,4-Methylphenyl Phosphate Synthase,P450 Monooxygenase,Nicotinamide Adenine Dinucleotide Phosphate,Nicotinamide Adenine Dinucleotide,5'-三磷酸腺苷,Magnesium Chloride,Manganese(Ll) Chloride,Alcohol Dehydrogenase,Aldehyde Dehydrogenase,Phosphohydrolase体系中,用 Aq. Buffer 作为反应溶剂,化学反应 4.0H,以21.2%的收率获得产物4-羟基苯丙酮
参考文献:通过化学模拟生物催化系统选择性氧化烷基酚中的脂肪族ch键
标题:通过化学模拟生物催化系统选择性氧化烷基酚中的脂肪族ch键
摘要:烷基酚中脂族c-h键的选择性氧化不仅在可用于合成各种下游化学产品的功能化中间体的产生中,而且在这些对环境有害的化合物的生物降解中都起着重要作用.化学选择性,区域选择性和立体选择性;可控性 环境影响是烷基酚化学氧化的主要挑战.在这里,我们报道了一种源自革兰氏阳性细菌谷氨酸棒杆菌的独特化学模拟生物催化系统的发展.由crehi(用于安装磷酸酯导向/锚定基团),Crejef / Creg / Crec(用于烷基酚的氧化)和cred(用于导向/锚定基团卸载)组成的系统能够选择性地氧化脂族c-H键的p-和米以可控的方式烷基化酚.此外,与两种代表性底物复合的中央p450生物催化剂crej的晶体结构为其底物的柔韧性和反应选择性提供了重要的结构见解.
DOI:10.1073/pnas.1702317114

专利信息

专利号:US-6252092-B1
优先权日:1999-04-30
标 题 :Process for synthesis of 5-alkylbenzodioxoles
发明人：BORZATTA VALERIO; BRANCALEONI DARIO; BATTISTINI CHRISTIAN
权利人:ENDURA SPA
摘要:The following description refers to a new process for the synthesis of 5-alkylated benzo[1,3]dioxole, comprising the following steps in sequence: catalytic hydrogenation of 4-acylphenol; acylation; displacement catalysed by Lewis acids; treatment with an inorganic basic compound and hydrogen peroxide; reaction with alkyl dihalides or dialkoxyalkanes. n The process described herein, which yields 5-alkylbenzo[1,3]dioxoles, is economic and can be easily scaled up to industrial size.

专利号:US-2014234364-A1
优先权日:2011-09-23
标 题:Total synthesis and immunological evaluation of saccharide moieties of the lipopolysaccharide from neisseria meningitidis
发明人：SEEBERGER PETER H; YANG YOU; ANISH CHAKKUMKAL; REINHARDT ANIKA
权利人:MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V
摘要:The present invention relates to the total chemical synthesis of the monosaccharide 35 # (R′â•?H), the disaccharide 36 # (R′≠H; R″â•?H), the trisaccharide 37 # (R′≠H; R″≠H; R′″≠H) and the tetrasaccharide 1 # (R′≠H; R″≠H; R′″≠H) of the following general formula wherein R represents —Y—NH 2 Y represents a linker R′ is H or R″ is H or R′″ is H or of the lipopolysaccharide from Neisseria meningitidis , as well as to the trisaccharide 37 # and the tetrasaccharide 1 # , to vaccines containing at least one of the saccharides 1 # , 35 # , 36 # , and 37 # and to the use of such vaccine for immunization against diseases caused by infection with bacteria containing the tetrasaccharide α-GlcNAc-(1→2)-α-Hep-( 1→3 )-α-Hep-(1→5)-α-Kdo or the trisaccharide α-Hep-(1→3)-α-Hep-(1→5)-α-Kdo or α-GlcNAc-(1→2)-±-Hep-(1→3)-α-Hep, especially for immunization against meningitis, septicaemia, pneumonia and nasopharyngitis caused by Neisseria meningitidis.

专利号:US-10844047-B2
优先权日:2018-06-21
标题:Process for the preparation of bazedoxifene
发明人：FERRARI MASSIMO; ZANI DANIELE DE; VEZZOSI STEFANO; BELOTTI PAOLO
权利人:ERREGIERRE SPA
摘要:The invention relates to a process for preparation of the compound 3-methyl-5-benzyloxy-2-(4-benzyloxyphenyl)-1H-indole 5, an intermediate for the synthesis of bazedoxifene and bazedoxifene acetate.

专利号:US-5074974-A
优先权日:1990-06-08
标题 :Electrochemical synthesis and simultaneous purification process
发明人：TOOMEY JR JOSEPH E
权利人:REILLY IND INC
摘要:A process in which an electrochemical cell is used to simultaneously conduct a product synthesis and purification while also regenerating conductive material. The improved process is applied to an electrochemical synthesis which is conducted by electrolyzing a working electrolyte into which ions selectively flow, as through an ion-exchange membrane, from a counter electrolyte. The improvement comprises the step of purifying a previously electrolyzed working electrolyte by including it in or as a counter electrolyte in a subsequent synthesis.

专利号:US-6005103-A
优先权日:1993-11-19
标题 :Pyrone derivatives as protease inhibitors and antiviral agents
发明人：DOMAGALA JOHN MICHAEL; LUNNEY ELIZABETH; PARA KIMBERLY SUZANNE; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
权利人:WARNER LAMBERT CO
摘要:The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.

专利号:US-2357985-A
优先权日:1940-07-30
标 题:Synthesis of hexoestrol
发明人：WALLIS EVERETT S; SEYMOUR BERNSTEIN
权利人:RESEARCH CORP