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- InChIKey: OQWIKYXFAZAALW-FMDYKLJDSA-N
- InChI=1S/C11H19NO9/c12-4(10(18)19)1-2-6(14)21-11-9(17)8(16)7(15)5(3-13)20-11/h4-5,7-9,11,13,15-17H,1-3,12H2,(H,18,19)/t4-,5+,7+,8-,9+,11+/m0/s1
- 计算化学: 氢键受体数*氢键供体数*可旋转键数*
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专利信息
专利号:US-2005287169-A1
优先权日:2003-06-17
标 题 :Methods of use of genes of pyridoxal 5'-phosphate biosynthesis in Bacillus subtilis: avirulent strains for vaccines, and methods for identification of antibacterial agents
发明人:BELITSKY BORIS R
权利人:BELITSKY BORIS R
摘要:Methods and compositions comprising a pathogenic bacterial strain having a non-reverting mutation in a pdx gene encoding an enzyme involved in pyridoxal-5′-phosphate synthesis are provided, for use in vaccines, and methods for identification of inhibitors of the enzyme for use as an antibacterial agent are provided.
专利号:US-7427690-B2
优先权日:2004-06-05
标 题 :Multifunction “crown complexesâ€? from amino acids and peptides for skin and hair restoration
发明人:GUPTA SHYAM K
权利人:BIODERM RESEARCH
摘要:This invention relates to Schiff's bases derived from amino acids and hydroxyaryl alkyl ketones, or a plant extract containing the same, having general chemical structure in FIG. 1 for topical application. This invention also relates to certain metal complex of said Schiff's bases, which have a crown-like appearance in their three-dimensional chemical structure, as in FIG. 2 . The Schiff's bases and their metal complexes of the present invention are useful for the modulation of metal-activated enzymes and metalloenzymes, such as Phenylalanine Hydroxylase, Tyrosine Transaminase, Phenylalanine Transaminase, Tyrosinase, various MMP (Matrix metalloproteases), Superoxide dismutase, 5-Alpha Reductase, and citrate lyase. These are further suitable for multifunctional topical methods for skin whitening, skin wrinkles reduction, skin antiaging, collagen synthesis, acne control, hair loss prevention, hair graying control, and facial oil control.