📜8-溴辛酸乙酯置于氢氧化钾,一水合肼体系中,用 水,二乙二醇 作为反应溶剂,化学反应 2.0H,反应生成 三十一烷酸 参考文献:Synthesis And Physical Properties Of Normal Higher Alcohols. Ii. Synthesis Of Normal Higher Primary Alcohols Of Odd Carbon Numbers From Heptacosanol To Heptatriacontanol 标题:Synthesis And Physical Properties Of Normal Higher Alcohols. Ii. Synthesis Of Normal Higher Primary Alcohols Of Odd Carbon Numbers From Heptacosanol To Heptatriacontanol 摘要: DOI:10.1246/bcsj.33.531
专利号:US-9643915-B2 优先权日:2013-03-15 标题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins 发明人:ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK 权利人:CERENIS THERAPEUTICS HOLDING SA 摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.
专利号:US-9708354-B2 优先权日:2013-03-15 标 题:Methods for the synthesis of sphingomyelins and dihydrosphingomyelins 发明人:ONICIU DANIELA CARMEN; HECKHOFF STEFAN; OSWALD BENOIT; REBMANN PETER; PEER ANDREAS; GONZALEZ MIGUEL; SAUTER PATRIK 权利人:CERENIS THERAPEUTICS HOLDING SA 摘要:The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.
专利号:US-12018313-B2 优先权日:2016-12-28 标题:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles 发明人:EMBREE MALLORY 权利人:NATIVE MICROBIALS INC 摘要:Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles, including dosed microbial ensembles and inoculative microbial ensembles, are disclosed.
专利号:US-11583842-B2 优先权日:2019-07-24 标题 :Zwitterionic catalysts for (trans)esterification: application in fluoroindole-derivatives and biodiesel synthesis 发明人:YEUNG YING-YEUNG; LAM YING-PONG; KE ZHIHAI; WANG XINYAN; TAN FEI; NG WING-HIN; TSE YING-LUNG STEVE 权利人:UNIV HONG KONG CHINESE 摘要:An amide/iminium zwitterion catalyst has a catalyst pocket size that promotes transesterification and dehydrative esterification. The amide/iminium zwitterions are easily prepared by reacting aziridines with aminopyridines. The reaction can be applied a wide variety of esterification processes including the large-scale synthesis of biodiesel. The amide/iminium zwitterions allow the avoidance of strongly basic or acidic condition and avoidance of metal contamination in the products. Reactions are carried out at ambient or only modestly elevated temperatures. The amide/iminium zwitterion catalyst is easily recycled and reactions proceed in high to quantitative yields.
专利号:US-11981938-B2 优先权日:2017-10-05 标 题 :Microorganisms and methods for the fermentation of cannabinoids 发明人:SZAMECZ BELA KRISZTIAN; VARSZEGI SZILVIA; NEMETH ATTILA; SZABO LORAND; KUMAR ABHINAV 权利人:ELESZTO GENETIKA INC 摘要:Disclosed herein are microorganism and methods that can be used for the synthesis of cannabigerolic acid (CBGA) and cannabinoids. The methods disclosed can be used to produce CBGA, Δ9-tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), cannabichromenic acid (CBCA), Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD), cannabichromene (CBC). Enzymes useful for the synthesis of CBGA and cannabinoids, include but are not limited to acyl activating enzyme (AAE1), polyketide synthase (PKS), olivetolic acid cyclase (OAC), prenyltransferase (PT), THCA synthase (THCAS), CBDA synthase (CBDAS), CBCA synthase (CBCAS), HMG-Co reductase (HMG1), and/or farnesyl pyrophosphate synthetase (ERG20). The microorganisms can also have one or more genes disrupted, such as gene that that controls beta oxidation of long chain fatty acids.
专利号:US-2022170057-A1 优先权日:2019-04-11 标题:Microorganisms and methods for the fermentation of cannabinoids 发明人:SZAMECZ BELA KRISZTIAN; VARSZEGI SZILVIA; NEMETH ATTILA; SZABO LORAND 权利人:ELESZTO GENETIKA INC 摘要:Disclosed herein are microorganism and methods that can be used for the synthesis of cannabigerolic acid (CBGA) and cannabinoids. The methods disclosed can be used to produce CBGA, Δ 9 -tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), cannabichromenic acid (CBGA), Δ 9 -tetrahydrocannabivarinic acid (THCVA), cannabidivarinic acid (CBDVA), cannabichromevarinic acid (CBCVA), Δ 9 -tetrahydrocannabinol (THC), cannabidiol (CBD), cannabichromene (CBC). Enzymes useful for the synthesis of CBGA and cannabinoids, include but are not limited to acyl activating enzyme (AAE1), polyketide synthase (PKS), olivetolic acid cyclase (OAC), prenyltransferase (PT), THCA synthase (THCAS), CBDA synthase (CBDAS), CBC A synthase (CBCAS), HMG-Co reductase (HMG1), and/or famesyl pyrophosphate synthetase (ERG20). The microorganisms can also have one or more genes disrupted, such as gene that that controls beta oxidation of long chain fatty acids.
[参考文献]: Aruna Gorusupudi, Et Al. Associations Of Human Retinal Very Long-Chain Polyunsaturated Fatty Acids With Dietary Lipid Biomarkers. J Lipid Res. 2016 Mar;57(3):499-508. [参考文献]: Khozirah Shaari, Et Al. Chemical Constituents Of Melicope Ptelefolia. Nat Prod Commun. 2011 Mar;6(3):343-8. [参考文献]: Shinji Sugihara, Et Al. Possible Biosynthetic Pathways For All Cis-3,6,9,12,15,19,22, 25,28-Hentriacontanonaene In Bacteria. Lipids. 2010 Feb;45(2):167-77. [参考文献]: Taro Motoigi, Et Al. Fatty Acid And Hydrocarbon Composition In Tropical Marine Shewanella Amazonensis Strain Sb2B(T). J Basic Microbiol. 2011 Oct;51(5):484-9.
合成参考文献
参考文献:10.1007/s00425-006-0328-7 摘要:Lozovaya V, Ulanov A, Lygin A, Duncan D, Widholm J. Biochemical features of maize tissues with different capacities to regenerate plants. Planta. 2006 Nov;224(6):1385–99. doi: 10.1007/s00425-006-0328-7. 参考文献:10.1007/s11103-006-9041-y 摘要:Li P, Sioson A, Mane SP, Ulanov A, Grothaus G, Heath LS, Murali TM, Bohnert HJ, Grene R. Response diversity of Arabidopsis thaliana ecotypes in elevated [CO2] in the field. Plant Mol Biol. 2006 Nov;62(4-5):593–609. doi: 10.1007/s11103-006-9041-y.