CAS: 38214-46-9; 6-Aminopyrimidine-4-Carboxylic Acid
该化合物是一种多用途有机化合物,在制药研究中具有重要应用性.该化合物的特点是以氨基和碳本体酸组为替代的火药环,为各种合成变异提供了一个平台. 它的主要优势包括高纯度,稳定性以及参与多种化学反应的能力,使其成为药物发现和药用化学的宝贵工具.
相似化合物
2173116-22-6 1824286-73-8 77817-12-0物理性质
MSDS等安全信息
上下游产品
CAS号81333-07-5 4-Pyrimidinecar... | CAS号77817-12-0 6-氨基嘧啶-4-羧酸甲酯合成工艺路线路线简述
📜6-氨基-4-嘧啶甲酰胺置于硫酸体系中,化学反应生成 6-氨基嘧啶-4-羧酸
参考文献:Bredereck Et Al.,Chemische Berichte,1956,Vol. 89,P. 12,14,17
标题:Bredereck Et Al.,Chemische Berichte,1956,Vol. 89,P. 12,14,17
海关参考信息
- 2905110000-甲醇
2912110000-甲醛
2915110000-甲酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10570114-B2
优先权日:2016-05-19
标题:Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
发明人：FISK JASON S; LI XIAOYONG; Muehlfeld Mark; BAUMAN ROBERT S; OPPENHEIMER JOSSIAN; TU SIYU; NITZ MARK A; CHAKRABARTI REETAM; FEIST SHAWN D; RINGER JAMES W; LENG RONALD B
权利人:DOW AGROSCIENCES LLC
摘要:Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.
专利号:US-2018334444-A1
优先权日:2016-05-19
标 题:Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
专利号:US-2018334445-A1
优先权日:2016-05-19
标题:Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
专利号:EP-3458442-A1
优先权日:2016-05-19
标 题 :Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
专利号:AU-2017268424-A1
优先权日:2016-05-19
标题:Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
专利号:CN-109415319-A
优先权日:2016-05-19
标 题 :Synthesis of Aryl Carboxylate by Direct Suchuki Coupling
