CAS: 350-46-9; 1-Fluoro-4-Nitrobenzene

上下游产品

fluorobenzene nitro acetate 4-nitrobenzenediazonium tetrafluoroborate 4-nitro-aniline 1-(4-nitrophenyl)piperidine 4'-fluoroacetanilide 4-Hydroxy-4'-nitrodiphenylamine N-(4-nitrophenyl)cyclohexylamine

4-氟苯硼酸置于zirconyl Nitrate Monohydrate,碘体系中,用 甲苯 用作溶剂,化学反应 14.0H,以86%的收率获得对氟硝基苯
参考文献:硝酸氧氮锆为硝化物种的分子碘催化的室温便捷芳基硼酸异丙基硝化:实验和理论研究
标题:硝酸氧氮锆为硝化物种的分子碘催化的室温便捷芳基硼酸异丙基硝化:实验和理论研究
摘要:一个简单而方便的方案已被开发用于本位在室温下通过分子碘催化的芳基硼酸的-Nitration,使用硝酸氧锆作为硝化物质.该方案适用于在温和的反应条件下,电子分离的芳基和杂芳基硼酸部分具有非常好的分离产率.此外,已对相同的反应进行了理论研究,并使用现代密度泛函理论(dft)对反应曲线进行了建模.基于dft的结果支持实验观测到的结果.
Doi:10.1002/aoc.4951

专利信息

专利号:US-6448446-B1
优先权日:2000-01-12
标 题 :Synthesis of N,N-disubstituted-p-phenylenediamine
发明人：TANG LI; TAN YUYING
权利人:ANTICANCER INC
摘要:An improved synthesis of N,N,-disubstituted-p-phenylene-diamine (DSPDA) preferably di-n-butyl-p-phenylenediamine is disclosed. The improvement rests on the discovery that DSPDA and its salts are extremely sensitive to oxygen so that once the product DSPDA or its salt is formed, oxygen must be excluded from all manipulations.

专利号:US-5354439-A
优先权日:1990-07-16
标 题 :Process for the synthesis of fluorinated derivatives
发明人：FORAT GERARD; GILBERT LAURENT; LANGLOIS BERNARD
权利人:RHONE POULENC CHIMIE
摘要:A process for the synthesis of fluorinated organic compounds and a reagent suitable for use in the process. The process is carried out by exchange with fluorides, while preferably agitating the reaction medium with ultrasonic sound.

专利号:US-2023399302-A1
优先权日:2020-10-29
标题:Process for the preparation of heteroaryl-substituted sulfur(vi) compounds
发明人：LOPCHUK JUSTIN M; SHULTZ ZACHARY P; SCATTOLIN THOMAS
权利人:H LEE MOFFITT CANCER CT & RES
摘要:The present disclosure provides processes for the synthesis of organic compounds, in particular processes for the synthesis of heteroaryl-substituted sulfur(VI) compounds by nucleophilic aromatic substitution.

专利号:US-8304409-B2
优先权日:2002-07-03
标 题:Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
发明人：EARL RICHARD A; EZAWA MAIKO; FANG XINQIN; GARVEY DAVID S; GASTON RICKY D; KHANAPURE SUBHASH P; LETTS L GORDON; LIN CHIA-EN; RANATUNGE RAMANI R; RICHARDSON STEWART K; SCHROEDER JOSEPH D; STEVENSON CHERI A; WEY SHIOW-JYI
权利人:EARL RICHARD A; EZAWA MAIKO; FANG XINQIN; GARVEY DAVID S; GASTON RICKY D; KHANAPURE SUBHASH P; LETTS L GORDON; LIN CHIA-EN; RANATUNGE RAMANI R; RICHARDSON STEWART K; SCHROEDER JOSEPH D; STEVENSON CHERI A; WEY SHIOW-JYI; NICOX SA
摘要:The invention describes novel nitrosated nonsteroidal antiinflammatory drugs (NSAIDs) and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated NSAID, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or at least one therapeutic agent. The invention also provides novel compositions comprising at least one nitrosated NSAID, and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one nitrosated NSAID, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides methods for treating inflammation, pain and fever; for treating gastrointestinal disorders; for facilitating wound healing; for treating and/or preventing gastrointestinal, renal and/or respiratory toxicities resulting from the use of nonsteroidal antiinflammatory compounds; for treating inflammatory disease states and/or disorders; and for treating and/or preventing ophthalmic diseases and/or disorders.

专利号:WO-2025097020-A1
优先权日:2023-11-02
标题:Process for polyethylene glycol synthesis
发明人：WANG PENG; ZHANG CHENGZHI; GUO ZHIWEI; SONG LICHENG
权利人:DESIGN THERAPEUTICS INC
摘要:The present disclosure relates to a process for the synthesis of polyethylene glycol (PEG) derivatives.

专利号:US-6197920-B1
优先权日:1999-07-21
标 题:Formulation for the production of 1, 3-bis (4-aminophenoxy) naphthalene and its polymer
发明人：CHENG KUN LIN; CHEN WEN-TUNG
权利人:CHINA TEXTILE INST
摘要:The present invention relates to the synthesis of new type of diamine monomer, 1,3-bis(4-amonophenoxy)naphthalene, and with such a compound to produce a series of aromatic polymers, including polyamide, polyimide, copoly(amide-imide)s, etc., such polymers having excellent resistance to heat and mechanical properties.