CAS: 3317-61-1; 5,5-Dimethyl-1-Pyrroline N-Oxide

该化合物是一种稳定的硝氧基,通常用于化学各个领域,特别是电磁共振光谱学,其特点是独特的结构,包括一个具有5级和1氧化氮功能组两个甲基组的火龙环,众所周知,DMPO能够捕捉自由基,使它成为研究生物和化学系统激进机制的宝贵工具.该化合物一般是无色的,不染黄色液体或固体,视其形态而定,在水和酒精等极地溶剂中溶解.其环境条件稳定,可以对激进物种进行长期研究.此外,DDPO在生物化学和药理学领域也有应用,用来调查氧化压力和相关现象.

结构式图片

相似化合物

157230-67-6 61856-99-3 706-50-3

上下游产品

CAS号57620-49-2 4-甲基-4-硝基戊醛 | CAS号57620-56-1 2-(3-甲基-3-硝基丁基)... | CAS号61856-91-5 5,5-dimethyl-1-... | CAS号40314-06-5 4-甲基邻苯二甲酰亚胺 | CAS号40936-29-6 (4,4'-dimethoxy... | CAS号106-68-3 3-辛酮 | CAS号35018-15-6 2,2-二甲基吡咯烷 | CAS号623580-01-8 2,2-二甲基吡咯烷盐酸盐 | CAS号167772-85-2 5-diethoxyphosp... | CAS号23581-42-2 HEXAHYDRO-1H-QU... | CAS号106051-14-3 hexahydrospiro[... | CAS号106051-18-7 2-(2'-oxobutyli... | CAS号146954-59-8 5,5-二甲基脯氨酸

合成工艺路线路线简述

    📜2,2-Dimethyl-5-Hydroperoxy-1-Pyrrolidinyloxyl 以 二甲基亚砜 作为反应溶剂,化学反应生成 5,5-二甲基-1-吡咯啉-N-氧化物
    参考文献:Tuccio,Beatrice; Lauricella,Robert; Frejaville,Claudine,Journal Of The Chemical Society. Perkin Transactions Ii,1995,# 2,P. 295-298
    标题:Tuccio,Beatrice; Lauricella,Robert; Frejaville,Claudine,Journal Of The Chemical Society. Perkin Transactions Ii,1995,# 2,P. 295-298

    专利信息


    专利号:US-10471096-B2
    优先权日:2015-01-06
    标题:Medicinal composition, blood treatment device, cosmetic, food and drink using combustion synthesis material
    发明人:YAMADA OSAMU; MARUO JUNPEI
    权利人:YAMADA OSAMU; OSU CORP
    摘要:Disclosed are a pharmaceutical composition, cosmetic product, and food or drink product each comprising a porous ceramic obtained by combustion synthesis of a starting material comprising (1) titanium and (2) at least one member selected from the group consisting of carbon, boron, nitrogen, and silicon; a pharmaceutical composition and cosmetic product each comprising a radical- and nanobubble-containing liquid; and a blood treatment device comprising a blood flow channel for extracorporeal circulation of a patient's blood, the blood flow channel being provided with the porous ceramic above, and the porous ceramic and the blood are brought into contact with each other.

    专利号:US-7157477-B2
    优先权日:2000-10-25
    标题 :Aliphatic amino-substituted demethoxylated hypocrellins and their synthesis
    发明人:ZHANG MANHUA; XU SHANGJIE; WU TAO; CHEN SHEN; SHEN TAO
    权利人:INST OF PHOTOGRAPHIC CHEMISTRY
    摘要:The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these compositions are disclosed. The present invention relates to the field of photosensitizers possessing photodynamic activities. They possess high photodynamic activities and low dark toxicities, which makes them as more potent photodynamic agents than HPD against cancer and AIDS virus.

    专利号:US-2007282078-A1
    优先权日:2006-06-01
    标题:Synthesis of aryl N-acylurea from aryl isocyanates or aryl carbodiimides for use as intermediate in novel sequential self-repetitive reaction (SSRR) to form amides, amide-imides and their polymers
    发明人:DAI SHENGHONG A; LIN JIANG-JEN; WEI KUAN-LIANG; WU CHIH-HENG; HUANG WEI-HSIANG
    权利人:DAI SHENGHONG A; LIN JIANG-JEN; WEI KUAN-LIANG; WU CHIH-HENG; HUANG WEI-HSIANG
    摘要:Disclosed is a process for synthesizing an aryl N-acylurea in both high selectivity and high yield, comprising reacting an aryl carbodiimide with a carboxylic acid under mild conditions. Thermolysis of N-acylureas at above about 120° C. gives amides and isocyanates, and the latter will undergo the repetitive reaction sequences in the presence of a carbodiimide catalyst. Based on this unique model, a sequential self-repetitive reaction (SSRR) is also developed in a versatile manner for converting aryl carbodiimides into amides, polyamides, polyamide-imides and polyamide-imide elastomers.

    专利号:US-2025257486-A1
    优先权日:2024-02-09
    标题 :Electrocatalyst for efficient nitrite reduction
    发明人:FAN ZHANXI; WANG YUNHAO; Xiong Yuecheng
    权利人:UNIV CITY HONG KONG
    摘要:The present invention reports the general one-pot synthesis of IrNi-based nanostructures with unconventional hexagonal close-packed (hcp) phase. Notably, the as-synthesized hcp IrNi nanostructures demonstrate excellent catalytic performance towards electrochemical nitrite reduction for ammonia synthesis. Ex/in-situ characterizations and theoretical calculations reveal that the Ir—Ni interactions within hcp IrNi-based nanostructures improve electron transfer to benefit both nitrite activation and active hydrogen generation, leading to a stronger reaction trend of NO 2 RR by greatly reducing energy barriers of rate-determining step.

    专利号:US-5922335-A
    优先权日:1995-05-15
    标 题:Uses for ascorbyl-phosphoryl-cholesterol in topical compositions
    发明人:PTCHELINTSEV DMITRI
    权利人:AVON PROD INC
    摘要:Novel uses of 3'-(L-ascorbyl-2-o-phosphoryl)-cholesterol, 3'-(L-ascorbyl-3-o-phosphoryl)-cholesterol, structural or functional isomers thereof and salts thereof (referred to collectively as 'APC compounds') are disclosed. Such novel uses include a method of reducing epidermal synthesis of abnormal elastin, especially epidermal synthesis of abnormal elastin that results from exposure to UV radiation. Also disclosed is a novel method of stimulating keratinocyte formation of triglycerides. In addition, a novel method of achieving antioxidant activity, both in the skin and also in topical compositions, is disclosed.

    专利号:US-5900227-A
    优先权日:1996-06-17
    标题 :Multicyclic nitrone spin trapping compositions
    发明人:JANZEN EDWARD G; SANKURATRI NAGARAJU
    权利人:OKLAHOMA MED RES FOUND
    摘要:Multicyclic nitrone spin trapping compounds capable of forming stable free radical spin adducts are provided as well as methods for their synthesis. The multicyclic nitrone spin trapping compounds can be reacted with a free radical, such as a hydroxy or hydroperoxy radical, in solution to form a spin adduct which is stable and readily detectable by electron paramagnetic resonance (EPR) spectroscopy. The multicyclic nitrone spin traps can be used to detect free radicals in a sample such as a biological system. In one embodiment, the spin trapping compound, 1,3,3-trimethyl-6-azabicyclo-[3.2.1]oct-6-ene-N-oxide ('TRAZON') is provided, as well as methods for the synthesis of TRAZON and of modified forms of TRAZON. TRAZON can react with a wide range of different free radicals in solution to form free radical spin adducts which are readily detectable by EPR.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/s00775-010-0628-z
    摘要:Zobel E, Yavin E, Gottlieb HE, Segal M, Fischer B. Oligonucleotides are potent antioxidants acting primarily through metal ion chelation. JBIC Journal of Biological Inorganic Chemistry. 2010 Feb 13;15(4):601–20. doi: 10.1007/s00775-010-0628-z.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知