专利号:CN-113603687-A 优先权日:2021-08-02 标 题:A new method for the synthesis of cyano-substituted imidazo[1,5-a]pyridines
专利号:US-2008269233-A1 优先权日:2005-08-04 标 题:Piperidinoyl-Pyrrolidine and Piperidinoyl-Piperidine Compounds 发明人:ANDREWS MARK DAVID; BROWN ALAN DANIEL; SEBASTIEN DAVID; LANSDELL MARK IAN 权利人:ANDREWS MARK DAVID; BROWN ALAN DANIEL; SEBASTIEN DAVID; LANSDELL MARK IAN 摘要:The present invention relates to a class of compounds of general formula (I) n n n n n n n n n n and the salts, hydrates, solvates, polymorphs and prodrugs wherein n, R 6 , R 7 and R 10 are as defined herein and especially to MCR4 agonist compounds of formula (I), to their use in medicine, particularly in the treatment of sexual dysfunction and obesity, to intermediates useful in their synthesis and to compositions containing them.
专利号:US-8138188-B2 优先权日:2006-02-23 标题 :Melanocortin type 4 receptor agonist piperidinoylpyrrolidines 发明人:ANDREWS MARK DAVID; BROWN ALAN DANIEL; LANSDELL MARK IAN; SUMMERHILL NICHOLAS WILLIAM 权利人:ANDREWS MARK DAVID; BROWN ALAN DANIEL; LANSDELL MARK IAN; SUMMERHILL NICHOLAS WILLIAM; PFIZER 摘要:The present invention relates to a class of melanocortin MCR4 agonists of general formula (I) n nwherein the variables and substituents are as defined herein and especially to selective MCR4 agonist compounds, to their use in medicine, particularly in the treatment of sexual dysfunction and obesity, to intermediates useful in their synthesis and to compositions containing them.
参考文献:10.1134/s1070363218030234 摘要:Sonyanaik B, Ashok K, Rambabu S, Ravi D, Kurumanna A, Madhu P, Sakram B. Facile One Pot Multi-Component Solvent-Free Synthesis of 2,4,5-Trisubstituted Imidazoles Using “Green” and Expeditious Ionic Liquid Catalyst under Microwave Irradiation. Russian Journal of General Chemistry. 2018 Mar;88(3):537–40. doi: 10.1134/s1070363218030234.