CAS: 13505-01-6; 3-Fluoro-4-Nitropyridine

相似化合物

2247-88-3 769-54-0 1805578-52-2

上下游产品

3-bromo-4-nitropyridine (S)-tert-butyl (1-(4-nitropyridin-3-yl)piperidin-3-yl)carbamate N-(3-(1H-pyrazol-1-yl)pyridin-4-yl)-2,3-dichlorobenzenesulfonamide 3-fluoro-pyridin-4-ylamine

📜3-溴-4-硝基吡啶置于四丁基氟化铵体系中,用 四氢呋喃,二甲基亚砜 用作溶剂,化学反应生成3-氟-4-硝基吡啶,3-溴-4-氟吡啶
参考文献:Synthesis Of Meta-Substituted [18F]-3-Fluoro-4-Aminopyridines By Direct Radiofluorination Of Pyridine N-Oxides
标题:Synthesis Of Meta-Substituted [18F]-3-Fluoro-4-Aminopyridines By Direct Radiofluorination Of Pyridine N-Oxides
摘要:本文披露了一种用于含有至少一个脱离基团的芳香n-杂环n-氧化物的氟化方法.这些n-氧化物可以被还原为氟化芳香n-杂环胺类似物.这种新颖的氟化方法可以成功地用于合成标记有18F的芳香n-杂环化合物.

专利信息

专利号:US-2017355648-A1
优先权日:2016-04-26
标题 :Synthesis of meta-substituted [18f]-3-fluoro-4-aminopyridines by direct radiofluorination of pyridine n-oxides

专利号:US-10160695-B2
优先权日:2016-04-26
标 题 :Synthesis of meta-substituted [18F]-3-fluoro-4-aminopyridines by direct radiofluorination of pyridine N-oxides
发明人：BRUGAROLAS PEDRO
权利人:UNIV CHICAGO
摘要:Disclosed herein are methods for the fluorination aromatic N-heterocyclic N-oxides that comprise at least one leaving group. The N-oxides may be reduced to the fluorinated aromatic N-heterocyclic amine analogs. This novel fluorination approach may be successfully applied for synthesizing aromatic N-heterocyclic compounds labeled with 18 F.

专利号:US-8362019-B2
优先权日:2008-02-01
标 题:Synthesis and anti-proliferative effect of substituted imidazo[4,5-b]pyrazine compounds
发明人：WINFIELD LEYTE L
权利人:SPELMAN COLLEGE; WINFIELD LEYTE L
摘要:This invention provides for compounds, compositions, and methods that involve anti-proliferative and anti-neoplastic activity in cancer cells. In particular, a series of benzimidazole, purine, imidazopyridine, and imidazopyrizine compounds having selected substitution patterns are disclosed, and the activity of various subject compounds is demonstrated. In particular, the disclosure provides for substituted imidazo[4,5-b]pyrazine compounds having the general formula n ntheir salts, pharmaceutical compositions, and methods of treatment using the subject compounds and compositions.

专利号:US-2012095009-A1
优先权日:2008-02-01
标题 :Synthesis and anti-proliferative effect of benzimidazole derivatives

专利号:US-2012095037-A1
优先权日:2008-02-01
标题:Synthesis and anti-proliferative effect of benzimidazole derivatives

专利号:US-8334302-B2
优先权日:2008-02-01
标题:Synthesis and anti-proliferative effect of substituted imidazo[4,5-b]pyridine compounds