CAS: 862129-81-5; 2-(3,6-Dihydro-2H-Thiopyran-4-yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
该化合物是一种含有黄有机化合物,其独特的结构特征包括二氧基罗内环和四氢基双氧基甲酸盐.该化合物一般呈现无色的黄色外观,在有机溶剂中可溶解,这在许多化合物中很常见.二氧基罗烷功能组的存在表明有机合成中的潜在应用,特别是在形成黄酸酯方面,这些酯是各种化学反应(包括交叉反应)中有价值的中间体.四氢基环可能会产生特定的再活动性或稳定性,影响其在化学过程中的行为.此外,多种甲基组的存在会助长阻塞,从而影响化合物的再活性和与其他分子的相互作用.
- 英文名称2-(3,6-Dihydro-2H-Thiopyran-4-yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
- 中文名称3,6-二氢-2H-噻喃-4-硼酸频哪醇酯
- IUPAC名称2-(3,6-dihydro-2H-thiopyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- 其它别名2-(3,6-二氢-2H-硫代吡喃-4-基)-4,4,5,5-四甲基-1,3,2-二氧杂环戊硼烷; 3,6-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-2H-Thiopyran; 4,4,5,5-Tetramethyl-2-(Tetrahydro-2H-Thiopyran-4-yl)-1,3,2-Dioxaborolane
- CAS编号862129-81-5
- MFCD编号:MFCD10700154
- EINECS号:691-334-1
- 分子式:C11H19BO2S分子量:226.15
- 产品CID: 1863122
- 产品分类有机原料→分子砌块→脂肪杂环类化合物→其它脂肪杂环类化合物
相似化合物
1370535-33-3 141091-37-4 287944-16-5物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报合成工艺路线路线简述
- 1072-72-6 + 37595-74-7 = 862129-81-5
反应条件:1.1 Reagents: Lithium Bis(Trimethylsilyl)Amide Solvents: Tetrahydrofuran; 2 H,-78 °C1.2 12 H,-78 °C -> Rt1.3 Reagents: Ammonium Chloride Solvents: Water2.1 Reagents: Potassium Acetate Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane; 2 H,80 °C
标题:Synthesis Of Functionalized [3],[4],[5] And [6]Dendralenes Through Palladium-Catalyzed Cross-Couplings Of Substituted Allenoates
作者:Lippincott,Daniel J.; Et Al
参考文献:Angewandte Chemie 日期:2017 卷标:56(3) 页码:847-850]
181180-42-7 + 73183-34-3 = 862129-81-5
反应条件:1.1 Reagents: Potassium Acetate Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium Solvents: 1,4-Dioxane; 2 H,80 °C
标题:Synthesis Of Functionalized [3],[4],[5] And [6]Dendralenes Through Palladium-Catalyzed Cross-Couplings Of Substituted Allenoates
作者:Lippincott,Daniel J.; Et Al
参考文献:Angewandte Chemie 日期:2017 卷标:56(3) 页码:847-850]
1072-72-6 + 37595-74-7 = 862129-81-5
反应条件:1.1 Reagents: Lithium Diisopropylamide Solvents: Tetrahydrofuran2.1 Reagents: Potassium Acetate Catalysts: [1,1′-Bis(Diphenylphosphino)Ferrocene]Dichloropalladium
标题:Structure-Activity Relationships Of Serms Optimized For Uterine Antagonism And Ovarian Safety
作者:Richardson,Timothy I.; Et Al
参考文献:Bioorganic & Medicinal Chemistry Letters 日期:2007 卷标:17(13) 页码:3544-3549
📜四氢噻喃-4-酮置于1,1'-双(二苯膦基)二茂铁二氯化钯(II)二氯甲烷复合物,Potassium Acetate,Lithium Diisopropyl Amide体系中,用 四氢呋喃,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 32.67H,反应生成 3,6-二氢-2H-噻喃-4-硼酸频哪醇酯
参考文献: Biaryl Compounds Useful For The Treatment Of Human Diseases In Oncology,Neurology And Immunology[fr] Composés Biaryliques Utiles Pour Le Traitement De Maladies Humaines En Oncologie,Neurologie Et Immunologie
标题: Biaryl Compounds Useful For The Treatment Of Human Diseases In Oncology,Neurology And Immunology[fr] Composés Biaryliques Utiles Pour Le Traitement De Maladies Humaines En Oncologie,Neurologie Et Immunologie
摘要:本发明提供了作为bruton'S酪氨酸激酶抑制剂的化合物及其组合物,具有适用于同一目的的理想特性.
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905143000-叔丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9242998-B2
优先权日:2013-02-07
标题 :Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis C
发明人：HE SHUWEN; DAI XING; PALANI ANANDAN; NARGUND RAVI; LAI ZHONG; ZORN NICOLAS; XIAO DONG; DANG QUN; MCCOMAS CASEY C; LI PENG; PENG XUANJIA; SOLL RICHARD
权利人:HE SHUWEN; DAI XING; PALANI ANANDAN; NARGUND RAVI; LAI ZHONG; ZORN NICOLAS; XIAO DONG; DANG QUN; MCCOMAS CASEY C; LI PENG; PENG XUANJIA; SOLL RICHARD; MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
