专利号:WO-2014029013-A1 优先权日:2012-08-22 标题:Method for producing silver(i) orthoperiodates 发明人:NADWORNY PATRICIA L; PROSPERI-PORTA GRAEME; UNRAU KEVIN R 权利人:INNOVOTECH INC 摘要:The present invention relates to the synthesis of silver(I) orthoperiodates, preferably Ag 5 IO 6 . The synthesis process comprises mixing in an aqueous solution a hydroxide, a periodate, and a source of single valency silver ions; and allowing the silver(I) orthoperiodate to form.
专利号:US-5334588-A 优先权日:1987-02-25 标 题 :Composition for inhibiting transmission of hepatitis B virus 发明人:FOX CHARLES L JR; MODAK SHANTA M 权利人:UNIV COLUMBIA 摘要:PCT No. PCT/US89/04642 Sec. 371 Date Jun. 4, 1991 Sec. 102(e) Date Jun. 4, 1991 PCT Filed Oct. 17, 1989 PCT Pub. No. WO90/04390 PCT Pub. Date May 3, 1990.The present invention relates to methods of inhibiting transmission of Hepatitis B virus using compositions comprising silver sulfadiazine and preferably further comprising a biguanide such as chlorhexidine and/or a detergent such as sodium deoxycholate. It is based, at least in part, on the discovery that silver sulfadiazine alone or in combination with chlorhexidine or sodium deoxycholate was shown to inhibit Hepatitis B virus DNA synthesis. The inhibitory effect of silver sulfadiazine was enhanced by combining silver sulfadiazine with either chlorhexidine or sodium deoxycholate.
摘要:L808: ATSDR - Agency for Toxic Substances and Disease Registry (1990). Toxicological profile for silver. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). 摘要:A245: Kim S, Choi JE, Choi J, Chung KH, Park K, Yi J, Ryu DY: Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells. Toxicol In Vitro. 2009 Sep;23(6):1076-84. doi: 10.1016/j.tiv.2009.06.001. Epub 2009 Jun 7. 摘要:A246: Dillard CJ, Tappel AL: Mercury, silver, and gold inhibition of selenium-accelerated cysteine oxidation. J Inorg Biochem. 1986 Sep;28(1):13-20.