CAS: 5831-59-4; 2-((Tetrahydrofuran-2-yl)Methoxy)Ethanol

该化合物是一种有机化合物,具有乙醚和酒精功能组的特征,具有四氢呋喃环,有助于其循环结构和潜在反应性.甲氧基甲醚组的存在表明,它有一个与四氢呋喃混合物混合物相连的甲氧替代物,提高了其在有机溶剂中的溶解性.该化合物一般是一种无色的黄色液体,其气味较轻.它以中度极化为名,在各种化学应用中有用,包括作为溶剂或有机合成的中间体.该化合物的结构允许氢结合,这可能影响其物理特性,例如沸点和粘度.此外,它可能具有低毒性,但在处理化学物质时始终应采取安全防范措施.

结构式图片

相似化合物

52814-38-7 62435-71-6 854702-18-4

欧盟法规

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上下游产品

oxirane Tetrahydrofurfuryl alcohol (Tetrahydrofuran-2-ylmethoxy)acetic Ethyl Ester 2-{[(2-bromoethyl)oxy]methyl}tetrahydrofuran

合成工艺路线路线简述

  • 合成目标产物 2-[(Tetrahydrofurfuryl)Oxy]Ethanol 主要起始原料 Ethyl 2-((Tetrahydrofuran-2-yl)Methoxy)Acetate
  • (文献来源)合成步骤主要原料 Ethyl 2-((Tetrahydrofuran-2-yl)Methoxy)Acetate
📜(Tetrahydrofuran-2-Ylmethoxy)Acetic Ethyl Ester置于lithium Aluminium Tetrahydride,水,Sodium Hydroxide体系中,用 乙醚 作为反应溶剂,化学反应 19.5H,反应生成 2-[(四氢糠基)氧基]乙醇
参考文献: Compounds[fr] Composés
标题: Compounds[fr] Composés
摘要:式(I)的化合物:其中r1是c1-6烷基氨基或c1-6烷氧基;m是一个值为2或3的整数;n是一个值为0至3的整数;p是一个值为1或2的整数;以及它们的盐是人类干扰素的诱导剂.诱导人类干扰素的化合物可能在治疗各种疾病中有用,例如治疗过敏性疾病和其他炎症性疾病,例如过敏性鼻炎和哮喘,治疗传染病和癌症,并且还可能作为疫苗佐剂有用.

海关参考信息

专利信息


专利号:US-11717498-B2
优先权日:2013-12-31
标题 :Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms
发明人:POPP KARL; MECKLER HAROLD
权利人:Chemapotheca LLC; PHARMAPOTHECA A INC
摘要:The invention also relates to pharmaceutical compositions comprising highly pure amphetamine and amphetamine-class compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds, and to methods of manufacturing, delivering, and using the amphetamine compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds.

专利号:US-2024308991-A1
优先权日:2021-01-15
标 题:Process for the synthesis of reactive carbohydrates including antigen precursors for conjugation with a carrier material
发明人:SHIAO TZE CHIEH; MIGNANI SERGE; MOFFETT SERGE; VISHWAKARMA RAM
权利人:KORANEX CAPITAL
摘要:Carbohydrate of Formula (A)where R1 is H and n an integer from 1 to 5, is synthesized by reacting, under heating, compound (A0)with HO—(CH2)n—CHâ•?CH2 in the presence of an acid capable of liberating a proton, and cooling the reaction mixture to obtain a cooled mixture comprising compound (A).Carbohydrate of Formula (AAPG)where R2 is a monovalent protecting group, PG is a divalent protecting group and n an integer from 1 to 5, is synthesized by reacting, in the presence of a metal-containing zeolite, compound of Formula (APG)with compound of Formula (A1)where X is —I, —Br, —Cl, —CN, —OTf (Triflate), —OMs (Mesylate), —OTs (Tosylate), methylsulfate, or trichloroacetimidate. Deprotection of compound (AAPG) forms compound (AA)Carbohydrates (A) and (AA) can be coupled with a thiolated linker to form glycoconjugate precursors, which in turn are conjugatable with a carrier material such as a protein, peptide or polypeptide.

专利号:US-12208068-B2
优先权日:2013-12-31
标题:Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms
发明人:POPP KARL; MECKLER HAROLD
权利人:PHARMAPOTHECA A INC
摘要:The invention also relates to processes for producing abuse deterrent pharmaceutical compositions comprising highly pure amphetamine and amphetamine-class compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds, and to methods of manufacturing, delivering, and using the amphetamine compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds.

专利号:US-8697730-B2
优先权日:2007-10-26
标题 :5-lipoxygenase activating protein (FLAP) inhibitor
发明人:REWOLINSKI MELISSA VIRGINIA; SCHAAB KEVIN MURRAY; KING CHRISTOPHER DAVID; STOCK NICHOLAS SIMON
权利人:REWOLINSKI MELISSA VIRGINIA; SCHAAB KEVIN MURRAY; KING CHRISTOPHER DAVID; STOCK NICHOLAS SIMON; PANMIRA PHARMACEUTICALS LLC
摘要:Described herein are methods for the synthesis of 3-[5-(pyridin-2-ylmethoxy)-3-(2-methyl-2-propylthio)-1-[4-(2-methoxypyridin-5-yl)benzyl]-indol-2-yl]-2,2-dimethyl-propionic acid, pharmaceutically acceptable salts, pharmaceutically acceptable solvates thereof. Also described are pharmaceutical compositions suitable for oral administration to a mammal that include, as well as methods of using such oral pharmaceutical compositions for treating respiratory conditions or diseases, as well as other leukotriene-dependent or leukotriene mediated conditions or diseases.

专利号:US-9314021-B2
优先权日:2004-11-03
标题 :Formulations containing insect repellent compounds
发明人:SCIALDONE MARK A
权利人:DU PONT
摘要:Dihydronepetalactone, a minor natural constituent of the essential oil of catmints ( Nepeta spp.) such as Nepeta cataria , has been identified as an effective insect repellent compound. Synthesis of dihydronepetalactone may be achieved by hydrogenation of nepetalactone, the major constituent of catmint essential oils. This compound, and compositions thereof, which also has fragrance properties, may be used commercially for its insect repellent properties.

专利号:GB-2631786-A
优先权日:2023-07-14
标题 :Novel synthesis of colloidal quantum dot ink and applications in semiconductor devices

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

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合成参考文献


摘要:Compound: Tetrahydrofurfuryl polyethylene glycol
参考文献:10.1007/978-1-4939-2938-2_12
摘要:Morille M, Venier-Julienne MC, Montero-Menei CN. Scaffolds for Controlled Release of Cartilage Growth Factors. Methods Mol Biol. 2015;1340():171–80. doi: 10.1007/978-1-4939-2938-2_12.
参考文献:10.1023/b:pham.0000008043.71001.43
摘要:Alsenz J, Haenel E. Development of a 7-day, 96-well Caco-2 permeability assay with high-throughput direct UV compound analysis. Pharm Res. 2003 Dec;20(12):1961–9. doi: 10.1023/b:pham.0000008043.71001.43.
参考文献:10.1208/pt020102
摘要:Ran Y, Zhao L, Xu Q, Yalkowsky SH. Solubilization of cyclosporin A. AAPS PharmSciTech. 2001 Jan 18;2(1):E2.
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