物理性质
- 熔点241°C
- 沸点156°C 2mm
- 闪点>65°C
- 密度1,0251 g/cm 3
- PSA:27.69
- LogP:3.7974
- 溶解性Very Soluble In Organic Solvents Like Alcohols, Benzene, Toluene And Xylene.
- 敏感性易受潮
- 外观形态白色至灰色粉末
- 储存条件 Sealed in dry, room temperature
- 产品应用该化合物用于美温-彭多夫-维利减少氯酮,积极参与1,1,12-三氧乙烯的制备,对1,1,2,2-四氧乙烷作出反应,然后消除酒精.
欧盟法规
ECHA物质ECHA物质C&L通报REACH预注册上下游产品
aluminium tert-butyl alcoholtert-butyl alcohol (benzoylacetonato)di-tert-butoxyaluminium di(tert-butoxy)aluminum hydridebenzophenone 1,1-Diphenylmethanol propiophenone 1-Phenyl-1-butanol 专利信息
专利号:WO-9419366-A1
优先权日:1993-02-26
标题 :Chemical synthesis of squalamine
发明人:MORIARTY ROBERT M; GUO LIANG; TULADHAR SUDERSAN M
权利人:MAGAININ PHARMA
摘要:Methods for the chemical preparation or synthesis of the sterol antibiotic squalamine. Preferably, the preparation is by modifying the 3-position of a 3-oxo-7α-hydroxy-24z-ether protected alcohol group-5α-cholestane with a spermidino moiety to form a 3β-spermidino-7α-hydroxy-24z-ether protected group -5α-cholestane; deprotecting the 24-position of the 3β-spermidino-7α-hydroxy-24z-ether protected group-5α-cholestane to the free hydroxyl; and sulfating the 24-position of the 3β-spermidino-7α, 24-dihydroxy-5α-cholestane.
专利号:US-12351558-B2
优先权日:2020-04-17
标题 :Process for the synthesis of lofexidine
发明人:NG CHOI I-TENG MONTSERRAT
权利人:MEDICHEM SA
摘要:The present invention relates to an improved process for the synthesis of lofexidine, or a pharmaceutically acceptable salt thereof, using an aluminium alkoxide as Lewis acid.
专利号:US-3959322-A
优先权日:1960-09-22
标 题:Synthesis of 13-alkyl-gon-4-ones
发明人:HUGHES GORDON ALAN; SMITH HERCHEL
权利人:SMITH HERCHEL
摘要:The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.
专利号:US-11753417-B2
优先权日:2019-01-17
标 题 :Synthesis of 14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene
发明人:GARA MOHAMAD; BECKER YIGAL
权利人:INT FLAVORS & FRAGRANCES INC
摘要:Disclosed is a scalable process for preparation of 14-methyl-16-oxabicyclo[10.3.1]hexadec-12-ene (BCE), a key intermediate for manufacture of fragrance ingredient 3-methylcyclopentadecenone (MUSCENONE®) and analogs through reaction of 3-Methyl-1,5-cyclopentadecanedione (MCPD) and analogs with a metal or metalloid alkoxide in high yield and purity.
专利号:US-2009131714-A1
优先权日:2005-06-08
标题:Synthesis of betulonic and betulinic aldehydes
发明人:KRASUTSKY PAVEL A; MUNSHI KALYAN
权利人:KRASUTSKY PAVEL A; MUNSHI KALYAN
摘要:The present invention provides for methods of selectively converting betulin to betulonic aldehyde. The present invention also provides for methods of selectively converting 3-substituted triterpen-28-ols to the corresponding 3-substituted triterpen-28-carboxaldehydes. Additionally, the present invention provides for methods of preparing betulonic aldehyde, betulonic acid, betulinic acid, and corresponding 3-substituted triterpenes.
专利号:US-8759584-B2
优先权日:2007-12-14
标 题 :Synthesis of biguanidines and triazines, and biguanidino-aluminium complexes as intermediates
发明人:FORD MARK JAMES
权利人:FORD MARK JAMES; BAYER CROPSCIENCE AG
摘要:Compounds of formula (I) or salts thereof, n nin which R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , X and Y are defined as in claim 1 , can be prepared by a process characterized in that a compound of the formula (II) or a salt thereof,n n nis reacted to a compound of the formula (III) or a salt thereof,n n nand an aluminium(III) source, optionally, in the presence of a protic additive or solvent selected from the group consisting of alcohols or amines.n n The compounds (I) are suitable to be used for the preparation of heterocyclic compounds corresponding to (I) where the group Al(X)(Y) is replaced with an optionally substituted carbon atom, or s-triazine derivatives thereof.