CAS: 55260-24-7; Boc-Gln(Xan)-Oh

上下游产品

CAS号90-46-0 占吨氢醇 | CAS号13726-85-7 B°C-L-谷氨酰胺

📜占吨醇,Boc-L-谷氨酰胺 以 溶剂黄146 作为反应溶剂,化学反应 63.0H,以39%的收率获得产物n-叔丁氧羰基-N'-(9-氧杂蒽基)-L-谷氨酰胺
参考文献:Atherton,Eric; Caviezel,Mario; Fox,Hazel,Journal Of The Chemical Society. Perkin Transactions I,1983,# 1,P. 65-73
标题:Atherton,Eric; Caviezel,Mario; Fox,Hazel,Journal Of The Chemical Society. Perkin Transactions I,1983,# 1,P. 65-73

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.