CAS: 482-53-1; 5-Hydroxy-3-(4-Hydroxyphenyl)-8,8-Dimethyl-6-(3-Methylbut-2-En-1-yl)-4H,8H-Pyrano[2,3-F]Chromen-4-One

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CAS号51225-28-6 6,8-二异戊烯基金雀异黄素 | CAS号5745-54-0 ISO-OSAJIN | CAS号5254-72-8 5-methoxy-3-(4-...

(E)-3-(Dimethylamino)-1-(2-Hydroxy-4,6-Bis(Methoxymethoxy)Phenyl)Prop-2-En-1-One置于吡啶,盐酸,Copper(L) Iodide,四(三苯基膦)钯,Tris(6,6,7,7,8,8-Heptafluoro-2,2-Dimethyl-3,5-octadionato)Europium(Iii),乙醇,水,碘,三氯化硼,Potassium Carbonate,Potassium Iodide,Potassium Hydroxide,Bis(Dibenzylideneacetone)-Palladium(0),三环己基膦体系中,用 四氢呋喃,1,4-二氧六环,甲醇,5,5-Dimethyl-1,3-Cyclohexadiene,乙醇,二氯甲烷,水,1,2-二氯乙烷,N,N-二甲基甲酰胺,甲苯 作为反应溶剂,化学反应 54.0H,反应生成 奥沙京
参考文献:天然异黄酮:Scandenone,Osajin 和 6,8-Diprenylgenistein 的全合成和抗菌研究
标题:天然异黄酮:Scandenone,Osajin 和 6,8-Diprenylgenistein 的全合成和抗菌研究
摘要:异黄酮是一类天然产物,具有多种有趣的生物特性,包括抗氧化,保肝,抗菌和抗炎活性. Scandenone (1),Osajin (2) 和 6,8-Diprenylgenistein (3) 是天然异戊二烯异黄酮,具有相同的多酚骨架.本研究以关键中间体15为原料合成天然异黄酮1-3,建立了直链和角吡喃异黄酮的立体选择性合成方法.还对1-3的抗菌活性进行了评价,它们均对革兰氏阳性菌表现出非常好的抗菌活性.其中,2是对mrsa最有效的一种,其mic值为2 μg/ml,Sem分析表明2可以破坏mrsa和粪肠球菌的细菌细胞膜.这些结果表明,异黄酮类型可以作为开发治疗革兰氏阳性细菌感染的新型抗菌剂的先导.
DOI:10.3390/molecules29112574

专利信息

专利号:US-2007232495-A1
优先权日:2006-03-24
标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
发明人：NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

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