CAS: 28862-80-8; Z-D-Met-Oh

相似化合物

4434-61-1 112883-40-6 1152-62-1

上下游产品

N-(benzyloxycarbonyl)methionine aniline ethanol D-methionineCarbobenzoxy-D-Met-Phe Carbobenzoxy-D-Met-D-Leu Carbobenzoxy-D-Met-D-Phe Carbobenzoxy-D-Met-D-Ala

📜Dl-蛋氨酸置于sodium Hydroxide体系中,化学反应生成N-苄氧羰基-D-蛋氨酸
参考文献:Dekker; Fruton,Journal Of Biological Chemistry,1948,Vol. 173,P. 471,475,476
标题:Dekker; Fruton,Journal Of Biological Chemistry,1948,Vol. 173,P. 471,475,476

专利信息

专利号:US-11634741-B2
优先权日:2013-11-20
标 题:Synthesis of L-nucleic acids by means of an enzyme
发明人：PECH ANDREAS; JAROSCH FLORIAN; JAHNZ MICHAEL; KLUSSMANN SVEN; DAVID RALF
权利人:APTARION BIOTECH AG
摘要:The present invention is related to a method for adding one or more L-nucleotides to the 3′end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising a mutant enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3′ end of the first L-nucleic acid, wherein the mutant enzymatic activity exhibiting moiety comprises an amino acid sequence, wherein the amino acids of the amino acid sequence are D-amino acids, wherein the mutant enzymatic activity exhibiting moiety is a variant of an enzymatic activity exhibiting moiety, wherein the enzymatic activity exhibiting moiety consists of an amino acid sequence according to SEQ ID NO: 15 and wherein the amino acids of the amino acid sequence according to SEQ ID NO: 15 are D-amino acids, wherein the amino acid sequence of the mutant enzymatic activity exhibiting moiety differs from the amino acid sequence of the enzymatic activity exhibiting moiety consisting of an amino acid sequence according to SEQ ID NO: 15 at least at one amino acid position, preferably at three amino acid positions, and/or wherein the amino acid sequence of the mutant enzymatic activity exhibiting moiety is a truncated form of an amino acid sequence according to SEQ ID NO: 15, and wherein the amino acid sequence of the mutant enzymatic activity exhibiting moiety is different from an amino acid sequence according to any of SEQ ID NOs 15 to 22 and 51.

专利号:US-2018208910-A1
优先权日:2012-05-16
标 题 :Enzymatic Synthesis of L-Nucleic Acids

专利号:EP-3071702-B1
优先权日:2013-11-20
标题 :Synthesis of l-nucleic acids by means of an enzyme

专利号:US-2016304926-A1
优先权日:2013-11-20
标题:Synthesis of L-Nucleic Acids by Means of an Enzyme

专利号:EP-2850192-B1
优先权日:2012-05-16
标 题 :Enzymatic synthesis of l-nucleic acids

专利号:WO-2013170963-A2
优先权日:2012-05-16
标题 :Enzymatic synthesis of l-nucleic acids