CAS: 18053-31-1; N-[3-Chloro-2-[[methyl-(2-Morpholin-4-Yl-2-Oxoethyl)Amino]Methyl]Phenyl]Benzamide

该化合物是属于苯胺的化学化合物,主要因其应用于药理学领域而得到承认,特别是抗口炎;复合物的特性使其能与三胺受体发生相互作用,从而减轻与干燥热和泌尿素等条件有关的过敏反应和症状;Fominoben的特征是水溶性相对较低,会影响其生物利用率和药用动力学;此外,它可能拥有特定受体地点的中度至高度亲近性,有助于其作为抗口炎的功效;与许多药物一样,安全性特征,包括潜在的副作用和抗药性,对于治疗用途至关重要;

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      专利号:WO-2020225409-A1
      优先权日:2019-05-09
      标 题:Process for a continuous synthesis of a cha zeolitic material from an emulsion
      发明人:SCHREYER HANNAH; PARVULESCU ANDREI-NICOLAE; MUELLER ULRICH; OKUBO TATSUYA; WAKIHARA TORU; IYOKI KENTA; LIU ZHENDONG
      权利人:BASF SE; UNIV TOKYO
      摘要:The present invention relates to a continuous process for preparing a zeolitic material comprising YO 2 and optionally X 2 O 3 in this its framework structure, wherein Y is a tetravalent element and X is a trivalent element, said process comprising. (i) providing a flow reactor comprising a reaction zone; (ii) continuously passing a reactant stream through the reaction zone according to (i), wherein the reactant stream comprises a reactant mixture comprising a non-polar liquid solvent system, one or more emulsifiers, and a mixture of one or more sources of YO 2 , optionally one or more sources of X 2 O 3 , seed crystals, a polar protic liquid solvent system, and one or more tetraalkylammonium cation containing compounds as structure directing agent; (iii) subjecting the reactant stream to crystallization conditions in the reaction zone and removing a product stream from the reaction zone, wherein the product stream comprises the zeolitic material. Furthermore, the invention further to a zeolitic material obtainable and/or obtained according to the inventive process, as well as to the use of said zeolitic material.

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      1: Baldino F Jr, Krespan B, Geller HM. Anticonvulsant actions of fominoben: possible involvement of benzodiazepine receptors. Pharmacol Biochem Behav. 1984 Jul;21(1):137-43. German. German. German. German. German. German. German. German. German. German. German. Chinese. German. German. German. German.
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