CAS: 13735-81-4; Trimethyl[(1-Phenylvinyl)Oxy]Silane

该化合物是一种该化合物是一种该化合物是一种该化合物是一种代用品和条件的等效物.它与一系列试剂和条件的兼容性使其在制药和精细化学应用中成为有用的中间体.由于湿度敏感,建议对惰性进行适当的处理.

结构式图片

相似化合物

14642-79-6 58518-77-7 55991-66-7

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

n-butyllithium chloro-trimethyl-silane carbon monoxide acetophenone 1-phenylhexane-1,5-dione 4-Methyl-1-phenyl-hexane-1,5-dione 3,3-dichloro-1-phenyl-propenone diethyl phosphonoacetophenone

合成工艺路线路线简述

    1-Phenyl-2-(Trimethylsilyl)Ethanone置于mercury(II) Iodide体系中,化学反应生成1-苯基-1-三甲基硅氧乙烯
    参考文献:将β-甲硅烷基酮重排为o-甲硅烷基取代的烯醇
    标题:将β-甲硅烷基酮重排为o-甲硅烷基取代的烯醇
    摘要:报道了将β-甲硅烷基酮重排为o-甲硅烷基取代的烯醇的条件.讨论了酮-烯醇体系中有机硅o-和c-衍生物的不可逆异构化机理.
    Doi:10.1016/0022-328X(68)80019-1

    海关参考信息

    专利信息


    专利号:US-4215044-A
    优先权日:1979-04-23
    标题:Synthesis of α-fluorocarbonyl compounds
    发明人:MIDDLETON WILLIAM J
    权利人:DU PONT
    摘要:Process for preparing an organic compound of the formula R 2 R 2 CFC(O)R 3 , which process comprises contacting and reacting in a reaction mixture which includes an inert solvent, at a temperature of -40° C. to -100° C., ROF and ##STR1## R is polyfluoroperhaloalkyl of 1-6 carbon atoms or FOCF 2 ; R 1 is hydrocarbyl of 1-6 carbon atoms; n each R 2 is selected from H, alkyl of 1-17 carbon atoms, cycloalkyl of 3-6 carbon atoms, aryl, heteroaryl and such alkyl, cycloalkyl, aryl and heteroaryl substituted by halogen or alkoxy of 1-6 carbon atoms; n R 3 is selected from H, alkyl and haloalkyl of 1-16 carbon atoms, cycloalkyl of 3-10 carbon atoms, aryl and haloaryl, OSi(R 1 ) 3 , OH, NH 2 , alkoxy of 1-6 carbon atoms, aryloxy, NHR 1 and NR 1 2 wherein R 1 is alkyl of 1-6 carbon atoms, N-arylamino and nitrogen or sulfur heterocyclic of 4-5 carbon atoms; n R 3 and one R 2 taken together is a diradical which with the Câ•?C group is carbocyclic, heterocyclic or haloheterocyclic, and recovering from the reaction mixture the compound of the formula R 2 R 2 CFC()R 3 .

    专利号:US-7968734-B2
    优先权日:2004-07-01
    标 题 :Organocatalysts and methods of use in chemical synthesis
    发明人:WANG WEI; WANG JIAN; LI HAO
    权利人:STC UNM
    摘要:The present invention pertains generally to compositions comprising organocatalysts that facilitate stereo-selective reactions and the method of their synthesis and use. Particularly, the invention relates to metal-free organocatalysts for facilitation of stereo-selective reactions, and the method of their synthesis and use.

    专利号:US-6005103-A
    优先权日:1993-11-19
    标题 :Pyrone derivatives as protease inhibitors and antiviral agents
    发明人:DOMAGALA JOHN MICHAEL; LUNNEY ELIZABETH; PARA KIMBERLY SUZANNE; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
    权利人:WARNER LAMBERT CO
    摘要:The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.

    专利号:JP-2001518393-A
    优先权日:1997-10-06
    标 题:Use of carbon-carbon bond forming synthesis of tris (trifluoromethylsulfonyl) methane and its alkali metal and alkaline earth metal salts, and a novel magnesium salt of tris (trifluoromethylsulfonyl) methane

    专利号:CN-106588811-A
    优先权日:2016-12-07
    标题 :A kind of method for the asymmetric synthesis of the benzoendosulphonamide compound containing chiral quaternary carbon center

    专利号:EP-0729465-B1
    优先权日:1993-11-19
    标 题:Pyrone derivatives as protease inhibitors and antiviral agents
    发明人:DOMAGALA JOHN MICHAEL; LUNNEY ELIZABETH; PARA KIMBERLY SUZANNE; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
    权利人:PARKE DAVIS & CO
    摘要:The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.
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    合成参考文献


    摘要:McKenna, C. E.; Kashemirov, B. A.; Błażewska, K. M., Science of Synthesis, (2009) 42, 901.
    摘要:Bauer, I.; Knölker, H.-J., Science of Synthesis, (2009) 46, 652.
    摘要:Bruffaerts, J.; Vasseur, A., Science of Synthesis Knowledge Updates, (2016) 2, 168.
    摘要:Dissanayake, P.; Averill, D. J.; Allen, M. J., Science of Synthesis Knowledge Updates, (2011) 4, 4.
    摘要:Gagnon, A.; Benoit, E.; Le Roch, A., Science of Synthesis Knowledge Updates, (2018) 4, 17.
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