CAS: 13651-55-3; 1-(Chloromethyl)-2,3-Dimethylbenzene

该化合物是一种氯化芳香化合物,其组成为附属于二甲基代苯环的氯甲基组,具有适合进一步功能化的回活动性,使其成为有机合成中有价值的中间体,特别是在生产药品,农用化学品和特殊化学品方面;电子捐赠的甲基组和电益氯甲基混合物的存在,增强了其在替代和混合反应中的多功能性;在标准储存条件下的稳定性确保合成应用的一贯性能;该化合物由于具有回活动性,通常在受控制的条件下处理,需要使用期间采取适当的安全措施;其定义明确的分子结构可以精确地纳入复杂的有机框架.

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    专利信息


    专利号:EP-1611083-B1
    优先权日:2003-03-25
    标 题:Synthesis of 2-chloromethyl-6-methylbenzoic acid esters
    发明人:MAIER CLAUS-JUERGEN; METZENTHIN TOBIAS; GRAESER JOACHIM; BICKER RICHARD; MANERO JAVIER
    权利人:SANOFI AVENTIS DEUTSCHLAND
    摘要:The invention relates to a method for producing compounds of formula (I) wherein R represents H, optionally halogen-substituted alkyl, cycloalkyl or aryl, alkyl-aryl or heteroaryl, and at least one CH2 group can be replaced by O in alkyl and cycloalkyl. Said compounds of formula (I) are valuable intermediates in the synthesis of PPAR agonists.

    专利号:US-6989462-B2
    优先权日:2003-03-25
    标题:Synthesis of 2-chloromethyl-6-methylbenzoic ester
    发明人:MAIER CLAUS-JUERGEN; METZENTHIN TOBIAS; GRAESER JOACHIM; BICKER RICHARD; MANERO JAVIER
    权利人:SANOFI AVENTIS DEUTSCHLAND
    摘要:A process is described for preparing compounds of formula (I) n nwhere R is H, optionally halogen-substituted alkyl, cycloalkyl, aryl, alkyl-aryl or heteroaryl, and, in alkyl and cycloalkyl, one or more CH 2 groups may be replaced by —O—. The compounds of the formula (I) are valuable intermediates in the synthesis of PPAR agonists.

    专利号:US-2004192956-A1
    优先权日:2003-03-25
    标题 :Synthesis of 2-chloromethyl-6-methylbenzoic ester

    专利号:RU-2193036-C2
    优先权日:1997-02-25
    标 题:Derivatives of imidazo[1,2-a]pyridine, methods of their synthesis, pharmaceutical preparation based on thereof, method of inhibition of gastric acid secretion, method of treatment of gastroenteric inflammatory diseases and method of treatment of states with helicobacter pylori infection

    专利号:CN-119661754-A
    优先权日:2024-12-30
    标 题 :Synthesis method of narrow distribution poly(p-acetoxystyrene) and copolymer thereof

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    合成参考文献


    参考文献:10.1007/bf00807400
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