CAS: 125700-71-2; O-(2-Oxo-1(2H)Pyridyl)-N,N,N',N'-Tetramethyluronium Tetrafluoroborate

1,1,3,3-四甲基脲 反应生成N-甲基甲酰胺
参考文献:Knorr,Reinhard;Trzeciak,Arnold;Bannwarth,Willi;Gillessen,Dieter,Tetrahedron Lett.,30,(1989) N5,C. 1927-1930
标题:Knorr,Reinhard;Trzeciak,Arnold;Bannwarth,Willi;Gillessen,Dieter,Tetrahedron Lett.,30,(1989) N5,C. 1927-1930

专利信息

专利号:US-7288661-B2
优先权日:2003-12-10
标 题 :Process for the synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]-octahydro-1H-indole-2-carboxylic acid compounds and application in the synthesis of perindopril
发明人：DUBUFFET THIERRY; LECOUVE JEAN-PIERRE
权利人:SERVIER LAB
摘要:Process for the synthesis of compounds of formula (I): n nwherein R represents a hydrogen atom or a protecting group for the amino function.n n Application in the synthesis of perindopril and pharmaceutically acceptable salts thereof.

专利号:US-6248891-B1
优先权日:1997-05-23
标题:Synthesis of acridine derivative multidrug-resistant inhibitors
发明人：SHARP MATTHEW JUDE; MADER CATHERINE J; STRACHAN CALUM
权利人:GLAXO WELLCOME INC
摘要:Synthesis of the MDRI of formula (I) from intermediates of acridone acid of formula (II) and aminophenethyl isoquinoline of formula (III), via steps including coupling and conversion to yield the MDRI of formula (I).

专利号:US-7973175-B2
优先权日:2005-09-28
标 题 :Synthesis of renin inhibitors involving a cycloaddition reaction
发明人：MICKEL STUART J; MARTERER WOLFGANG
权利人:NOVARTIS AG
摘要:The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula III, n nwherein R, R 1 , and R′ are as defined in the specification, or a salt thereof, and a compound of formula IVn n nwherein R, R 1 , R 2 and R′ are as defined in the specification, and processes of manufacturing these.

专利号:US-11708341-B2
优先权日:2016-08-05
标题:Synthesis of (S)-2-amino-4-methyl-((R)-2-methyloxirane-2-yl)-pentan-1-one and pharmaceutically acceptable salts thereof
发明人：Beaver Matthew; CUI SHENG; SHI XIANGQING
权利人:AMGEN INC
摘要:The present invention provides new methods for preparing compound 5, and pharmaceutically acceptable salts thereof, of structure n nCompound 5, or a pharmaceutically acceptable salt thereof, is an important intermediate in the synthesis of carfilzomib. The invention further provides methods of making a useful manganese catalyst that may be used in the epoxidation step of the present invention.

专利号:US-7279583-B2
优先权日:2003-12-10
标题:Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof
发明人：DUBUFFET THIERRY; LECOUVE JEAN-PIERRE
权利人:SERVIER LAB
摘要:Process for the industrial synthesis of perindopril of formula (I): n nand pharmaceutically acceptable salts thereof.

专利号:US-2024218014-A1
优先权日:2022-11-21
标 题:Synthesis of a cyclic peptide
发明人：BAUR PIUS BRUNO; CLEATOR EDWARD; DENIAU GILDAS; EISELE FRANK; FLÖGEL OLIVER; HUSTE ANJA; KEHL MARCEL ROMAN; LÖWENECK MARKUS; SILVA ROLANDO RAVELO; VORBERG RAFFAEL
权利人:JANSSEN PHARMACEUTICA NV
摘要:Processes for performing peptide synthesis, particularly for cyclic peptide synthesis are generally described. Reaction intermediates of the peptide synthesis are also described.