CAS: 88511-27-7; 4-Amino-3-Iodopyridine

相似化合物

211029-67-3 98136-86-8 800402-12-4

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CAS号504-24-5 4-氨基吡啶 | CAS号13534-98-0 3-溴-4-胺吡啶 | CAS号70298-89-4 4-(2,2,2-三甲基乙酰胺)吡啶 | CAS号113975-33-0 3-碘-4-(2,2,2-三甲... | CAS号211029-67-3 4-(B°C-氨基)-3-碘吡啶 | CAS号253-72-5 1,6-萘啶 | CAS号22930-75-2 3-甲基-1H-吡咯并[3,2-c]吡啶 | CAS号433728-73-5 2-(4-氨基-3-吡啶) N... | CAS号53439-83-1 5H-苯并[c][1,6]萘啶-6-酮 | CAS号52816-59-8 2-phenyl-1,6-na...

4-氨基吡啶置于硫酸,Potassium 4-Iodylbenzene-1-Sulfonate,碘体系中,用 水,乙腈 作为反应溶剂,化学反应 12.0H,以88%的收率获得产物4-氨基-3-碘吡啶
参考文献:4-碘基苯磺酸钾:制备,结构和作为芳烃氧化碘化试剂的应用
标题:4-碘基苯磺酸钾:制备,结构和作为芳烃氧化碘化试剂的应用
摘要:通过在水中用 Oxone 氧化 4-碘苯磺酸制备了一种新的高价碘 (V) 化合物,即 4-碘基苯磺酸钾.通过在水中用酸性形式的 Amberlyst 15 处理,该钾盐可以进一步转化为 4-碘基苯磺酸.4-碘基苯磺酸钾的单晶 X 射线结构揭示了由于许多分子内和分子间相互作用的组合,聚合物链在固态中的存在.4-碘基苯磺酸钾作为一种热稳定和水溶性的高价碘基氧化剂,可能会有许多实际应用,特别是用作芳族底物氧化碘化的试剂.
DOI:10.1002/ejoc.201201064

专利信息

专利号:US-3901899-A
优先权日:1973-04-27
标题 :Synthesis of indoles from anilines and intermediates therein
发明人：GASSMAN PAUL G
权利人:UNIV OHIO STATE RES FOUND
摘要:Preparing indoles and intermediates therefor by reacting an Nhaloaniline with a Beta -carbonylic hydrocarbon sulfide to form an azasulfonium halide, reacting the azasulfonium halide with a strong base to form a thio-ether indole derivative, and then reducing the thio-ether indole, e.g. with Raney nickel, to form the indole compound. When an acetal or ketal of the Beta carbonyl hydrocarbon sulfide is used, the azasulfonium salt is treated with a base, and then with an acid to form the thio-ether indole derivative. When an Alpha -ethyl- Beta -carbonylic hydrocarbon sulfide is used, the resulting azosulfonium salt reacts with strong base to form a thio-ether indolenine derivative, which on reduction with Raney nickel or complex metal hydrides yields 3-substituted indoles. The aniline may be an aminopyridine to form an aza-indole compound in the process. The azasulfonium salts and thio-ether indole or thio-ether indolenine derivatives can be isolated and recovered from their respective reaction mixtures. The thio-ether-indole and thio-ether indolenine derivatives are useful as intermediates to make the indoles without the thio-ether group. The indoles are known compounds having a wide variety of uses, e.g., in making perfumes, dyes, amino acids, pharmaceuticals, agricultural chemicals and the like.

专利号:US-3992392-A
优先权日:1973-04-27
标题:Synthesis of indoles from anilines and intermediates therein
发明人：GASSMAN PAUL G
权利人:UNIV OHIO STATE RES FOUND
摘要:Preparing indoles and intermediates therefor by reacting an N-haloaniline with a β-carbonylic hydrocarbon sulfide to form an azasulfonium halide, reacting the azasulfonium halide with a strong base to form a thio-ether indole derivative, and then reducing the thio-ether indole, e.g. with Raney nickel, to form the indole compound. When an acetal or ketal of the β-carbonyl hydrocarbon sulfide is used, the azasulfonium salt is treated with a base, and then with an acid to form the thio-ether indole derivative. When an α-ethyl-β -carbonylic hydrocarbon sulfide is used, the resulting azosulfonium salt reacts with strong base to form a thio-ether indolenine derivative, which on reduction with Raney nickel or complex metal hydrides yields 3-substituted indoles. The aniline may be an aminopyridine to form an aza-indole compound in the process. The azasulfonium salts and thio-ether indole or thio-ether indolenine derivatives can be isolated and recovered from their respective reaction mixtures. The thio-ether-indole and thio-ether indolenine derivatives are useful as intermediates to make the indoles without the thio-ether group. The indoles are known compounds having a wide variety of uses, e.g., in making perfumes, dyes, amino acids, pharmaceuticals, agricultural chemicals and the like.

专利号:US-2017355648-A1
优先权日:2016-04-26
标题 :Synthesis of meta-substituted [18f]-3-fluoro-4-aminopyridines by direct radiofluorination of pyridine n-oxides

专利号:US-10160695-B2
优先权日:2016-04-26
标 题 :Synthesis of meta-substituted [18F]-3-fluoro-4-aminopyridines by direct radiofluorination of pyridine N-oxides
发明人：BRUGAROLAS PEDRO
权利人:UNIV CHICAGO
摘要:Disclosed herein are methods for the fluorination aromatic N-heterocyclic N-oxides that comprise at least one leaving group. The N-oxides may be reduced to the fluorinated aromatic N-heterocyclic amine analogs. This novel fluorination approach may be successfully applied for synthesizing aromatic N-heterocyclic compounds labeled with 18 F.

专利号:CN-104262242-B
优先权日:2014-09-22
标题 :Synthesis of 3,5-diiodo-4-aminopyridine by in situ generation of iodo reagent

专利号:CN-104262242-A
优先权日:2014-09-22
标 题:Synthesis of 3,5-diiodo-4-aminopyridine by in situ generation of iodo reagent