CAS: 6228-73-5; Cyclopropanecarboxamide

相似化合物

2516-47-4 5500-21-0 7252-53-1

上下游产品

CAS号4023-34-1 环丙甲酰氯 | CAS号64969-79-5 Cyclopropancarb... | CAS号5500-21-0 环丙基腈 | CAS号63190-44-3 环丙烷甲酰亚氨酸乙酯盐酸盐 | CAS号765-43-5 环丙甲基酮 | CAS号628-20-6 4-氯丁腈 | CAS号141-52-6 乙醇钠 | CAS号5500-21-0 环丙基腈 | CAS号765-30-0 环丙胺 | CAS号73330-91-3 环丙基氨基甲酸甲酯 | CAS号20295-34-5 环丙烷硫代甲酰胺

环丙基腈置于没食子酸,Potassium Hydroxide体系中,用 乙醇,水 作为反应溶剂,以68%的收率获得产物环丙酰胺
参考文献:可再生生物资源中的没食子酸促进腈的有效水合
标题:可再生生物资源中的没食子酸促进腈的有效水合
摘要:已经开发出有效的没食子酸在室温下以乙醇/水作作为反应溶剂促进腈水合.本方案以中等至非常好的产率提供了多种酰胺.此外,五倍子提取物可以用作促进水合的促进剂,这也表明了天然原料的潜在利用.
DOI:10.1002/cctc.201700016

专利信息

专利号:EP-2644590-A1
优先权日:2012-03-30
标 题:Synthesis of 2-(3,4-difluorophenyl)cyclopropanamine derivatives and salts
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

专利号:US-9695169-B2
优先权日:2012-05-31
标 题:Synthesis of heterocyclic compounds
发明人：IBRAHIM PRABHA N
权利人:PLEXXIKON INC
摘要:Provided herein are intermediates and processes useful for facile synthesis of biologically active molecules.

专利号:EP-3617181-A1
优先权日:2018-08-30
标题:Synthesis of trans-2-phenylcyclopropylamine or a salt or solvate thereof
发明人：BREUNING ALEXANDER; LIMMERT MICHAEL; DELLING AXEL; HOFMEIER HARALD; HULTSCH JANA; MICKSCH MAIK; SOMMER CHRISTIAN
权利人:AREVIPHARMA GMBH
摘要:The present invention relates to the field of manufacturing trans-2-phenylcyclopropylamine or a salt or solvate thereof, in particular in the form of the sulphate salt. The obtained product, particularly when in the form of the synthesis of trans-2-phenylcyclopropylamine sulphate, is exceptionally pure, substantially free from reactants and reagents that are mutagenic, hazardous or of great concern to the health of humans or the environment.

专利号:US-2001047100-A1
优先权日:2000-04-26
标 题:Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives
发明人：KJAERSGAARD HANS JOERGEN; PHILLIPS JIM; ALI SYED M
摘要:Novel intermediates useful in the preparation of optically active H 3 histamine receptor antagonist 2-(4-imidazoyl)-cyclopropyl derivatives are disclosed.

专利号:US-8686145-B2
优先权日:2010-02-25
标 题 :Process for the preparation of α-acyloxy β-formamido amides
发明人：RUIJTER EELCO; ORRU ROMANO; ZNABET ANASS; POLAK MARLOES; TURNER NICHOLAS
权利人:RUIJTER EELCO; ORRU ROMANO; ZNABET ANASS; POLAK MARLOES; TURNER NICHOLAS; VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG C O TECHNOLO
摘要:The present invention relates to a process for the preparation of a compound of the general Formula (I), comprising: a) reacting a compound of the general Formula (II) with a compound of the Formula III R 2 COOH and a compound of the general Formula IV R 3 NC under such conditions that compound I is formed, wherein R 1 represents a substituted or unsubstituted alkyl, alkenyl, alkynyl, aromatic or non-aromatic, mono-, di- or tricyclic, or heterocyclic structure, and R 2 represents a substituted or unsubstituted alkyl, alkenyl, alkynyl, aromatic or non-aromatic, mono-, di- or tricyclic, or heterocyclic structure, and R 3 represents a substituted or unsubstituted alkyl, alkenyl, or alkynyl structure. In further aspect the subject invention relates to the use of the obtained products as intermediates for various peptidomimetics, and preferably as a building block in a convergent synthesis of prolyl dipeptide structures.

专利号:WO-2025078335-A1
优先权日:2023-10-09
标 题 :Processes for the preparation of deucravacitinib
发明人：ETAYO PÉREZ PABLO; PUJOL OLLÉ XAVIER; MOLINA NIETO JUAN
权利人:FARMHISPANIA GROUP S L
摘要:The invention relates to processes for the preparation of deucravacitinib of formula (XI), or a pharmaceutically acceptable salt thereof. It also relates to intermediates of formula (V') and (V'') as defined herein useful in the synthesis of this molecule.