CAS: 55757-60-3; (S)-Methyl 6-Amino-2-((Tert-Butoxycarbonyl)Amino)Hexanoate

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CAS号73548-77-3 N6-((苄氧基)羰基)-N2... | CAS号2389-45-9 N-B°C-N'-Cbz-L-赖氨酸 | CAS号108634-97-5 Nα-(tert-butoxy... | CAS号27894-50-4 CBZ-L-赖氨酸甲酯盐酸盐 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号62062-43-5 N-叔丁氧羰基-N'-生物素-L-赖氨酸

专利信息

专利号:US-8865935-B2
优先权日:2011-06-30
标题:Purification methods for betulonic acid and Boc-lysinated betulonic acid, and organic synthesis of betulonic acid amides with piperazine derivatives
发明人：CHUE KUCK-TACK; KIM TAE-HWAN; TEN LEONID
权利人:CHUE KUCK-TACK; KIM TAE-HWAN; TEN LEONID; KOREA ENERGY RESEARCH INST
摘要:The present invention provides a method of purifying betulonic acid contained the reaction product of organic synthesis of a Jones oxidation reagent and betulin extracted from the bark of a birch, a method of preparing a piperazine betulonic acid amide derivative, which is used as a chemical having an antibacterial function, using the high-purity betulonic acid obtained by the purification method and a derivative prepared by this method, a method of purifying a Boc-lysinated betulonic acid monomer ester contained in the reaction product of organic synthesis of lysine and the high-purity betulonic acid (starting material) obtained by the purification method, and a method of purifying Boc-lysinated betulonic acid contained in the reaction product of hydrolysis of the high-purity Boc-lysinated betulonic acid monomer ester.

专利号:US-2007196834-A1
优先权日:2005-09-09
标题:Method and system for the generation of large double stranded DNA fragments
发明人：CERRINA FRANCESCO; KAYSEN JAMES H; LI MO-HUANG; CHU LARRY L; BELSHAW PETER J; SUSSMAN MICHAEL R; RICHMOND KATHRYN
权利人:CERRINA FRANCESCO; KAYSEN JAMES H; LI MO-HUANG; CHU LARRY L; BELSHAW PETER J; SUSSMAN MICHAEL R; RICHMOND KATHRYN
摘要:Synthesis of long chain molecules such as DNA is carried out rapidly and efficiently to produce relatively large quantities of the desired product. The synthesis of an entire gene or multiple genes formed of many hundreds or thousands of base pairs can be accomplished rapidly and, if desired, in a fully automated process requiring minimal operator intervention, and in a matter of hours, a day or a few days rather than many days or weeks. Production of a desired gene or set of genes having a specified base pair sequence is initiated by analyzing the specified target sequence and determining an optimal set of subsequences of base pairs that can be assembled to form the desired final target sequence. The set of oligonucleotides are then synthesized utilizing automated oligonucleotide synthesis techniques. The synthesized oligonucleotides are subsequently selectively released from the substrate and used in a sequential assembly process.

专利号:US-7205385-B2
优先权日:2004-11-12
标 题:Polymerization method for the synthesis of polypeptide imaging agents
发明人：GRIMMOND BRIAN JAMES; MOASSER BAHRAM; AMARATUNGA MOHAN MARK
权利人:GEN ELECTRIC
摘要:A method for synthesizing extended poly(amino acids) conjugated to imaging agents, such as DTPA, is disclosed. The amino acid is initially conjugated to the imaging agent at the monomer stage, followed by formation of the corresponding N-carboxyanhydride. The method utilizes catalyzed ring opening polymerization of the N-carboxyanhydride of the amino acid-imaging agent monomer allowing the formation of a poly(amino acid) backbone having 100% imaging agent conjugation if desired. However, the present method also permits the degree of conjugation to be controlled by copolymerizing the N-carboxyanhydride of the amino acid-imaging agent monomer with one or more unconjugated monomers, i.e. N-carboxyanhydrides of the same or of other amino acids. Various imaging agents may be employed, and new hybrid random, block, and mixed copolymers may be prepared.

专利号:US-2006183888-A1
优先权日:2004-08-13
标 题:Pyrrolysine synthesis and modification
发明人：CHAN MICHAEL K; KRZYCKI JOSEPH A
权利人:CHAN MICHAEL K; KRZYCKI JOSEPH A
摘要:Synthetic L-pyrrolysine of formula I, and derivatives thereof, chemical methods of preparing these amino acids and derivatives, and methods of derivatizing these amino acids after incorporation into a peptide or protein. n nAlso provided are derivatives and methods of preparing derivatives, including addition of substituents at any substitutable position; modifications to the lysine alkyl chain; modifications of the pyrroline ring. Also provided are methods of adding labels to the pyrrolysine or derivative thereof.

专利号:WO-2025151642-A1
优先权日:2024-01-09
标题 :Modified elongation factor p and methods of use thereof
发明人：HECHT SIDNEY; DEDKOVA LARISA; POTUGANTI GAL REDDY; DASKALOVA SASHA
权利人:UNIV ARIZONA STATE
摘要:Provided herein are modified elongation factor P (EF-P) enzymes capable of incorporating noncanonical amino acids during protein synthesis at efficiencies that are different than those of native EF-P. Also provided are methods for preparing and using modified EF-P enzymes.

专利号:WO-9209300-A1
优先权日:1990-11-21
标 题:Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures