CAS: 555-84-0; Nifuradene

结构式图片

上下游产品

CAS号41401-76-7 1-氨基咪唑烷-2-酮 | CAS号698-63-5 5-硝基糠醛

合成工艺路线路线简述

    📜1-氨基咪唑烷酮,5-硝基糠醛 在 盐酸体系中,获得 1-<(5-Nitrofurfuryliden)Amino>-2-Imidazolidinon
    参考文献:Chemotherapeutic Nitrofurans. Iv.1 Some Derivatives Of 1-Amino-2-Imidazolidinone,1-Amino-2-Pyrrolidinone And 3-Amino-2-Thiazolidinone
    标题:Chemotherapeutic Nitrofurans. Iv.1 Some Derivatives Of 1-Amino-2-Imidazolidinone,1-Amino-2-Pyrrolidinone And 3-Amino-2-Thiazolidinone
    摘要:
    Doi:10.1021/Ja01601A052

    海关参考信息

    专利信息


    专利号:WO-0032619-A1
    优先权日:1998-11-30
    标题:Methods and compositions for identification of inhibitors of ribosome assembly
    发明人:DAMMEL CAROL S; WATSON JULIE C
    权利人:RIBOGENE INC
    摘要:The invention provides a means for identifying novel antibiotics by screening for compounds that inhibit bacterial ribosome assembly and ribosomal protein synthesis, which comprises the screening of test compounds to identify those that inhibit the activity of a bacterial ribosomal protein. The in vitro and in vivo assays detect (a) increased translation of a reporter mRNA that is normally repressed in the presence of a ribosomal protein, (b) increased growth in cells that over-express ribosomal protein, and (c) decreased binding of the ribosomal protein to its target RNA. The invention encompasses the (a) methods of screening and testing compounds by the above methods, (b) compounds that are identified in the assay which inhibit ribosome assembly and protein synthesis and (c) methods for treatment using said compounds.

    专利号:WO-2009056955-A1
    优先权日:2007-10-30
    标题 :Amine-bearing phospholipids (abps), their synthesis and use
    发明人:ZUMBUEHL ANDREAS
    权利人:UNIV BASEL; ZUMBUEHL ANDREAS
    摘要:Disclosed herein are amine-bearing phospholipids (ABP). The ABPs display many properties and functionalities of naturally occurring phospholipids, but also new properties and functionalities, such as the ability to polymerize while maintaining structural integrity, that may supplement or expand the functionalities of naturally occurring phospholipids.

    专利号:US-9907753-B2
    优先权日:2010-03-19
    标 题 :Lipid vesicle compositions and methods of use
    发明人:IRVINE DARRELL J; MOON JAEHYUN
    权利人:MASSACHUSETTS INST TECHNOLOGY
    摘要:The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.

    专利号:US-2014315720-A1
    优先权日:2012-10-24
    标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
    发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
    权利人:CELANESE ACETATE LLC
    摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Malin JM Jr, Anderson EE, Gleen JF. Clinical evaluation of nifuradene (NF-246): a preliminary report. J Urol. 1968 Mar;99(3):348-9. doi: 10.1016/s0022-5347(17)62707-1. 101(1):109-10. doi: 10.1016/s0022-5347(17)62287-0.
    7:510-2.

    合成参考文献


    摘要:Journal of Pharmacy and Pharmacology., 16(663), 1964 []
    摘要:Toxicology and Applied Pharmacology., 18(185), 1971 []
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知