CAS: 3066-90-8; 2,3-Dimethoxy-5-Methylbenzene-1,4-Diol

上下游产品

2,3-Dimethoxy-5-methyl-1,4-benzoquinone 2,3-dimethoxy-4-hydroxy-4-(1-propenyl)-2-cyclobuten-1-one ascorbic acid Ubisemihydroquinone ubiquinone-45 ubidecarenone 2-geranyl-5,6-dimethoxy-3-methyl-[1,4]benzoquinone R,11R)-trans-phytyl)-[1,4]benzoquinone2,3-dimethoxy-5-methyl-6-((7R,11R)-trans-phytyl)-[1,4]benzoquinone

📜3,4,5-三甲氧基甲苯置于sodium Tetrahydroborate,双氧水,溶剂黄146体系中,用 甲醇,乙醚,水 用作溶剂,化学反应 192.25H,反应生成2,3-二甲氧基-5-甲基-1,4-苯二酚
参考文献:Reductive Lactonization Of Strategically Methylated Quinone Propionic Acid Esters And Amides
标题:Reductive Lactonization Of Strategically Methylated Quinone Propionic Acid Esters And Amides
摘要:
Doi:10.1021/jo00275A012

专利信息

专利号:US-6686485-B2
优先权日:2001-04-19
标题:Synthesis of coenzyme Q10, ubiquinone
发明人：WEST DANIEL DAVID
摘要:Processes for the stereospecific synthesis of coenzyme Q10, ubiquinone, are disclosed; a semi synthetic procedure using solanesol derived from tobacco waste as the starting material. The process of the invention results in high yields of isometrically useful compositions containing the optically pure isomers.

专利号:US-3998858-A
优先权日:1975-12-12
标 题:Process for synthesis of coenzymes q
发明人：KIJIMA SHIZUMASA; YAMATU ISAO; HAMAMURA KIMIO; MINAMI NORIO; YAMAGISHI YOUJI; INAI YUICHI
权利人:EISAI CO LTD
摘要:2,3-DIMETHOXY-5-METHYL-6-SUBSTITUTED-1,4-BENZOQUINONE HAVING THE FORMULA: ##STR1## in which R is ##STR2## in which S is an integer of 0 to 11 and A and B stand for hydrogen or may form a direct bond, is prepared by reacting a boric acid ester of 2,3-dimethoxy-5-methyl-1,4-benzohydroquinone with prenol or isoprenol having the above group R and subsequently reacting the resulting borate with a mild oxidant. The compound is useful as coenzyme Q and has various clinical effects.

专利号:US-4057568-A
优先权日:1974-11-22
标 题:Process for synthesis of boric acid ester
发明人：KIJIMA SHIZUMASA; YAMATU ISAO; HAMAMURA KIMIO; MINAMI NORIO; YAMAGISHI YOUJI; INAI YUICHI
权利人:EISAI CO LTD
摘要:2,3-DIMETHOXY-5-METHYL-6-SUBSTITUTED-1,4-BENZOQUINONE HAVING THE FORMULA: ##STR1## in which S is an integer of 0 to 11 and A and B stand for hydrogen or may form a direct bond, n Is prepared by reacting boric acid ester of 2,3-dimethoxy-5-methyl-1,4-benzohydroquinone with prenol or isoprenol having the above group R and subsequently reacting the resulting borate with a mild oxidant. The compound is useful as coenzyme Q and has various clinical effects.

专利号:US-2002156302-A1
优先权日:2001-04-19
标 题:Synthesis of coenzyme Q10, ubiquinone

专利号:US-3939202-A
优先权日:1973-01-31
标题:Process for preparing polyene compounds
发明人：MATSUI MASANAO; KITAMURA SEIICHI; MORIOKA MASAHIRO
权利人:TEIKOKU CHEM IND CO LTD
摘要:Polyene compounds of the formula: ##EQU1## wherein R' is protected or unprotected hydroxyl or a group of the formula: ##EQU2## (in which R' and R'' are each carboxyl or a group convertible into carboxyl on hydrolysis), m is a positive integer and n is 0 or a positive integer, which are useful as intermediates in the synthesis of coenzyme Q, can be produced advantageously through a step for the dehydration of a compound of the formula: ##EQU3## wherein R', m and n are each as defined above.

专利号:US-2004151711-A1
优先权日:2001-04-19
标题 :Synthesis of coenzyme Q10, ubiquinone