CAS: 1945-84-2; 2-Ethynylpyridine

相似化合物

75867-46-8 30413-58-2 30413-54-8

上下游产品

CAS号86521-05-3 2-三甲基硅乙炔基吡啶 | CAS号1121-60-4 吡啶-2-甲醛 | CAS号90965-06-3 (1-重氮基-2-氧代丙基)膦酸二甲酯 | CAS号29767-97-3 4-2 -吡啶-2-甲基-3-丁基-2-醇 | CAS号109-04-6 2-溴吡啶 | CAS号1092543-20-8 (Z)-2-(2-iodovi... | CAS号1122-62-9 2-乙酰基吡啶 | CAS号109-09-1 2-氯吡啶 | CAS号38210-35-4 2-(2-吡啶基)苯并噻吩 | CAS号51035-40-6 2-(4-羟基苯基)吡啶 | CAS号6304-27-4 2-(2-二甲基氨基乙基)吡啶 | CAS号100-69-6 2-乙烯基吡啶 | CAS号1122-62-9 2-乙酰基吡啶 | CAS号13228-40-5 2-(2-吡啶基)吲哚 | CAS号35299-68-4 2-(5-pyridin-2-... | CAS号161395-83-1 (E)-2-(2-(4,4,5... | CAS号13141-43-0 2-(2-pyridin-2-... | CAS号29767-97-3 4-2 -吡啶-2-甲基-3-丁基-2-醇

2-碘吡啶置于甲醇,Bis-Triphenylphosphine-Palladium(II) Chloride,Copper(L) Iodide,三苯基膦,Potassium Hydroxide体系中,用 四氢呋喃,水 用作溶剂,化学反应 24.17H,反应生成2-乙炔基吡啶
参考文献:Rapid Consecutive Three-Component Coupling-Fiesselmann Synthesis Of Luminescent 2,4-Disubstituted Thiophenes And Oligothiophenes
标题:Rapid Consecutive Three-Component Coupling-Fiesselmann Synthesis Of Luminescent 2,4-Disubstituted Thiophenes And Oligothiophenes
摘要:(杂)芳酰氯,炔烃和乙基2-巯基乙酸酯可以在连续的三组分合成中反应,以非常好至优异的收率获得2,4-二取代的噻吩5-羧酸酯.在伪五组分反应的意义上,高度蓝色发光的對稱三噻吩和五噻吩可以以优异的收率合成.
Doi:10.1039/c2Cc17548G

专利信息

专利号:US-5434152-A
优先权日:1993-11-08
标题:Asymmetric synthesis of (S)-(-)-6-chloro-4- cyclopropyl-3,4-dihydro-4-[(2-pyridyl)ethynyl]-2(1H)-quinazolinone
发明人：HUFFMAN MARK A; YASUDA NOBUYOSHI; DECAMP ANN E; GRABOWSKI EDWARD J J
权利人:MERCK & CO INC
摘要:An asymmetric synthesis of (S)-(-)-6-chloro-4-cyclopropyl-3,4-dihydro-4-[(2-pyridyl)ethynyl]-2(1H)-quinazolinone comprises the chiral addition of 2-pyridylacetylide to N 1 -protected 6-chloro-4-cyclopropyl-2-quinazolinone followed by removal of the protecting group.

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-9982005-B2
优先权日:2013-04-04
标 题 :Macrolides and methods of their preparation and use
发明人：MYERS ANDREW G; SEIPLE IAN BASS; ZHANG ZIYANG
权利人:HARVARD COLLEGE
摘要:Provided herein are methods of preparing macrolides by the coupling of an eastern and western half, followed by macrocyclization, to provide macrolides, including both known and novel macrolides. Intermediates in the synthesis of macrolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using the inventive macrolides are also provided. A general diastereoselective aldol methodology used in the synthesis of the western half is further provided.

专利号:WO-2023203374-A1
优先权日:2022-04-20
标 题 :[1,2]selenazolo[2,3-a]pyridin-8-ium inhibitors of pyruvate kinase isoform m2
发明人：ARSENJANS PAVELS; DIMITRIJEVS PAVELS; MAKRECKA-KUKA MARINA
权利人:LATVIAN INST ORGANIC SYNTHESIS
摘要:The present invention relates to a novel isoselenazolopyridinium salts as anticancer agents by inhibiting pyruvate kinase isoform M2 (PKM2) activity, as well as methods of their manufacturing and use in different pharmaceutical compositions for the treatment of various diseases and disorders by administration of such substances.

专利号:WO-2008037604-A1
优先权日:2006-09-25
标 题 :Novel polybenzofulvene derivatives, synthesis and uses thereof
发明人：CAPPELLI ANDREA; GALEAZZI SIMONE; ANZINI MAURIZIO; VOMERO SALVATORE
权利人:UNIV SIENA; CAPPELLI ANDREA; GALEAZZI SIMONE; ANZINI MAURIZIO; VOMERO SALVATORE
摘要:The present invention relates to polymers of formula poly-3 (I), their synthesis, intermediates and uses thereof.

专利号:US-2003082830-A1
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products