CAS: 1694-29-7; 3-Chloropentane-2,4-Dione

该化合物是一种氯化二氯酮化合物,其分子式为C5H7ClO2, 具有反应性α-氯碳基化合物,使其成为有机合成的多功能中间体,特别是用于异环化合物形成和核生殖替代反应.氯和二氯酮的功能的存在增强了其在制药和农用化学应用中的效用,在制药和农用化学应用中,它作为活性成分的前体.其结构特性有利于选择性的修改,能够精确控制反应路径.该化合物通常在受控制的条件下处理,因为其具有反应性,确保合成工艺的稳定性和可复制性.

结构式图片

相似化合物

18115-70-3 135664-28-7 41564-69-6

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

acetylacetone sodioacetylacetone 1-hexene water 1-(2-methylimidazo[1,2-a]pyridin-3-yl)ethanone (3)H-imidazol-2-ylmercapto)-pentane-2,4-dione3-(4-phenyl-1(3)H-imidazol-2-ylmercapto)-pentane-2,4-dione 1-(4-methyl-thiazol-5-yl)-ethanone 5-acetyl-2,4-dimethylthiazole

合成工艺路线路线简述

    📜乙酰丙酮置于n-氯代丁二酰亚胺,Trityl Tetrafluoroborate体系中,用 二氯甲烷 用作溶剂,以50%的收率获得3-氯-2,4-戊二酮
    参考文献:碳阳离子作为路易斯酸催化剂:反应性和范围
    标题:碳阳离子作为路易斯酸催化剂:反应性和范围
    摘要:碳阳离子是一类潜在的路易斯酸,已被忽略不计,它是一种催化剂.在这里,我们展示了三芳基甲基离子作为有机反应的强力路易斯酸催化剂的潜力.三芳基甲基离子的路易斯酸度可以通过改变芳环的电子性质而容易地调节,并且碳正离子的催化活性显示出与阳离子碳上的空p C轨道的稳定水平直接相关.三芳基甲基离子作为有机反应的有效路易斯酸催化剂的多功能性已在diels-alder,Aza-diels-alder,共轭加成,卤化,环氧重排和分子内异戊烯反应中得到证明.
    Doi:10.1002/adsc.201400609

    海关参考信息

    专利信息


    专利号:US-6096898-A
    优先权日:1999-10-22
    标 题:One pot synthesis of 1,2,4-triazoles
    发明人:PODHOREZ DAVID E; HULL JR JOHN W; BRADY CHRISTINE H
    权利人:DOW AGROSCIENCES LLC
    摘要:One pot synthesis of 1,2,4-triazoles uses thioimidate intermediate and 1,2-dichloroethane solvent.

    专利号:US-7579472-B2
    优先权日:2004-09-28
    标题:Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
    发明人:MUDRYK BOGUSLAW M; CUNIERE NICOLAS; HSIEH DAU-MING; ROSSANO LUCIUS; LIANG JING; CHEN BANG-CHI; ZHANG HUIPING; ZHAO RULIN; WANG BEI; DAVID ADRIAN
    权利人:BRISTOL MYERS SQUIBB CO
    摘要:A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. n nThese compounds can be useful as factor Xa inhibitors.

    专利号:EP-0289036-A1
    优先权日:1987-04-30
    标题:Preparation of 3-chloro-4,5-difluorobenzotrifluoride
    发明人:MUNDHENKE RUDOLPH F; TANG DAVID Y
    权利人:OCCIDENTAL CHEM CO
    摘要:In the synthesis of 3-chloro-4,5-difluorobenzotrifluoride by reaction of KF with 3,5-dichloro-4-fluorobenzotrifluoride, the production of undesirable by-products, especially over-fluorinated materials such as trifluorobenzotrifluoride is minimized when the reaction is run at a temperature of 196° to 206° Celsius in the presence of N-methyl-2-pyrrolidone.

    专利号:WO-2011085684-A1
    优先权日:2010-01-15
    标 题:O-heterocyclyl formanilide compounds, their synthesis methods and use
    发明人:ZHANG XIANGNING; NI JUEPING; LIU LI; MA HAIJUN; GU LINLING; CAO BIN; ZHU HONGJUN; ZHANG YANNAN; ZHOU YALING; ZHANG HONGFEN; LI YUHAO; TAN HAIJUN; WANG NA; HE HAIBING; ZENG XIA
    权利人:JIANGSU PESTICIDE RES INST CO LTD; ZHANG XIANGNING; NI JUEPING; LIU LI; MA HAIJUN; GU LINLING; CAO BIN; ZHU HONGJUN; ZHANG YANNAN; ZHOU YALING; ZHANG HONGFEN; LI YUHAO; TAN HAIJUN; WANG NA; HE HAIBING; ZENG XIA
    摘要:O-heterocyclyl formanilide compounds represented by formula (I) or (II), their synthesis methods and use are disclosed. In the formulas, X 1 , X 2 , Z, R 1 or R 2 is defined as that in the description. The o-heterocyclyl formanilide compounds have good effect for preventing and curing harmful insects and can be used for preparing pesticides in the field of agriculture or gardening.

    专利号:US-7304157-B2
    优先权日:2004-09-28
    标题:Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones

    专利号:US-2007282106-A1
    优先权日:2004-09-28
    标 题 :EFFICIENT SYNTHESIS OF 4,5-DIHYDRO-PYRAZOLO[3,4-c]PYRID-2-ONES

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Götzinger, A. C.; Müller, T. J. J., Science of Synthesis Knowledge Updates, (2017) 3, 21.
    摘要:Zhang, J., Science of Synthesis Knowledge Updates, (2013) 2, 237.
    摘要:Herter, S.; Turner, N. J., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 82.
    摘要:Shaabani, A.; Sarvary, A.; Shaabani, S., Science of Synthesis: Multicomponent Reactions, (2013) 2, 55.
    摘要:Kwiecień, H. U., Science of Synthesis: Knowledge Updates, (2024) 3, 23.
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