CAS: 108448-77-7; (3Ar,6S,7As)-8,8-Dimethylhexahydro-1H-3A,6-Methanobenzo[c]Isothiazole 2,2-Dioxide

上下游产品

CAS号107869-45-4 (+)-10-樟脑磺内酰亚胺 | CAS号119944-89-7 (S)-(+)-丙烯酰-2,1... | CAS号193416-13-6 (S)-2-((4R,5S,6... | CAS号193416-24-9 (S)-2-((4R,5R,6... | CAS号35963-20-3 左旋樟脑磺酸 | CAS号94594-81-7 (S)-(+)-(2-丁烯酰)... | CAS号128947-19-3 N-丙酰基-(2S)-樟烷-1... | CAS号141993-16-0 N-乙酰基-(2R)-樟烷-1...

(R)-Camphorsulfonimine置于镍 氢气体系中,用 乙醇,水 用作溶剂,60.0 °C,600.01 Kpa 条件下,反应 5.0H,以93%的收率获得右旋樟脑磺内酰胺
参考文献:Wo2008/6394
标题:Wo2008/6394

专利信息

专利号:WO-2025149479-A1
优先权日:2024-01-12
标题:Synthesis of modified nucleoside triphosphates
发明人：KUCHELMEISTER HANNES; PFAFFENEDER TONI; MEX MARTIN; VETH SIMON; MENKE JAN-MICHAEL
权利人:ROCHE DIAGNOSTICS GMBH
摘要:The invention relates to a new diastereoselective synthesis method for highly modified nucleoside triphosphates with two conjugable groups. The method works in liquid phase with conventional laboratory equipment as used in any chemical laboratory or production. For this, a new chiral P(V) phosphorylation reagent has been designed that allows highly efficient diastereoselective synthesis under mild conditions. Overall, a highly efficient, diastereoselective, high quality, cost-effective synthetic method of modified nucleoside triphosphates has been developed.

专利号:US-7230119-B2
优先权日:2004-08-25
标 题 :Process for the preparation of substituted pyrrolidine derivatives and intermediates
发明人：CHAND POORAN; EL-KATTAN YAHYA; KOTIAN PRAVIN L
权利人:BIOCRYST PHARM INC
摘要:Two syntheses are provided; one for the preparation of (3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol, and other for the preparation of (3S,4R)-4-(hydroxymethyl)pyrrolidin-3-ol. (3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol is prepared using the achiral ylide prepared from benzylamine instead of phenethylamine (Scheme 3) which provides a crystalline intermediate. The synthesis of (3S,4R)-4-(hydroxymethyl)pyrrolidin-3-ol is achieved from (S)-diethylmalate as described in Scheme 4. A process for preparing camphor sultam is also provided.

专利号:US-2002156320-A1
优先权日:2000-01-13
标 题 :Enantioselective synthesis of valproic acid analogues
发明人：NAU HEINZ
摘要:This invention employs camphorsultam as a chiral recoverable auxiliary to provide a new method for manufacturing valproic acid and valproic acid amides that facilitates the enantioselective or diasteroselective production of valproic acid analogs on a larger scale.

专利号:CN-101020665-A
优先权日:2007-01-22
标题:A class of γ-aryl substituted chiral triazole fungicides and their synthesis method