CAS: 926-06-7; Isopropyl Methanesulfonate

相似化合物

16156-54-0 62-50-0 14245-62-6

上下游产品

methanesulfonic acid propene sodium isopropylate methanesulfonyl chloride2-isopropoxynaphthalene 1,3,5-triisopropyl benzene 2-methyl-3-°Ctyne isopropyl ethanesulfonate

甲基磺酰氯,异丙醇置于2,6-二甲基吡啶,硫酸体系中,化学反应 2.5H,以57%的收率获得产物甲磺酸异丙酯
参考文献:Studies On Chemical Carcinogens And Mutagens. Xxv. Chemoselectivity Of Alkyl Sulfonates Toward 4-(P-Nitrobenzyl)Pyridine (Nbp) In Phosphate Buffer.
标题:Studies On Chemical Carcinogens And Mutagens. Xxv. Chemoselectivity Of Alkyl Sulfonates Toward 4-(P-Nitrobenzyl)Pyridine (Nbp) In Phosphate Buffer.
摘要:合成了六种烷基磺酸和五种对取代苯磺酸的甲基,乙基和异丙基酯,并评估了它们在含有60%丙酮的磷酸盐缓冲液(ph 6.0)中对4-(对硝基苄基)吡啶(nbp)的烷基化能力.对nbp的化学选择性常数snbp被定义为用于nbp烷基化的烷基磺酸的摩尔分数与在缓冲介质中水解的剩余烷基化试剂的摩尔分数之比的对数.研究发现,Snbp不仅显著依赖于分子中烷基部分的结构,还明显依赖于离去的磺酸部分的电子性质.讨论了结构与化学选择性之间的关系.
DOI:10.1248/cpb.32.1326

专利信息

专利号:US-8314251-B2
优先权日:2008-03-07
标 题 :Total synthesis of salinosporamide A and analogs thereof
发明人：LING TAOTAO; DANISHEFSKY SAMUEL
权利人:LING TAOTAO; DANISHEFSKY SAMUEL; NEREUS PHARMACEUTICALS INC
摘要:The present application relates to certain compounds and to methods for the preparation of certain compounds that can be used in the fields of chemistry and medicine. Specifically, described herein are methods for the preparation of various compounds and intermediates, and the compounds and intermediates themselves. More specifically, described herein are methods for synthesizing Salinosporamide A and its analogs that includes forming a compound of formula (VIII).

专利号:US-2006111438-A1
优先权日:2004-10-21
标 题:Asymmetric synthesis of substituted dihydrobenzofurans
发明人：GONTCHAROV ALEXANDER V; KHAFIZOVA GULNAZ; POTOSKI JOHN R; YU QING; SHAW CHIA-CHENG; STACK GARY P; ZHOU DAHUI
权利人:WYETH CORP
摘要:The present invention concerns production of a compound of the formula n n nor a pharmaceutically acceptable salt thereof by a process which utilizes the cyclization of a compound of the formula: n n nwhere Ar, Y, R 1 , R y , R 2 , and m are as defined herein.

专利号:US-8268936-B2
优先权日:2005-01-04
标题:Synthesis of hybrid block copolymers and uses thereof
发明人：BREITENKAMP KURT; SILL KEVIN N
权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
摘要:The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.

专利号:US-2012196989-A1
优先权日:2005-02-11
标题:Synthesis of homopolymers and block copolymers
发明人：BREITENKAMP KURT; SILL KEVIN N
权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
摘要:The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.

专利号:US-2006172914-A1
优先权日:2005-01-04
标题:Synthesis of hybrid block copolymers and uses thereof

专利号:US-2009234137-A1
优先权日:2008-03-07
标题 :Total synthesis of salinosporamide a and analogs thereof