专利号:US-11999757-B2 优先权日:2017-11-01 标 题:Synthesis of boronate ester derivatives and uses thereof 发明人:BOYER SERGE HENRI; HECKER SCOTT J; VERZIJL GERARDUS K M; HERMSEN PETRUS J 权利人:MELINTA SUBSIDIARY CORP 摘要:Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.
专利号:US-10669292-B2 优先权日:2014-05-05 标 题 :Synthesis of boronate salts and uses thereof 发明人:HECKER SCOTT; BOYER SERGE 权利人:REMPEX PHARMACEUTICALS INC 摘要:Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.
专利号:US-8618281-B2 优先权日:2006-01-03 标 题 :Geometric synthesis of porphyrin rods 发明人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D 权利人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D; UNIV NORTH CAROLINA STATE 摘要:A method of making a compound of Formula I′ n ncomprises reacting a compound of the formula DLCHO, with a compound of the formulan n nto produce the compound of Formula I′. Methods of using the compounds are also described, particularly as intermediates for the synthesis of porphyrin rods, which porphyrin rods are in turn useful for (among other things) the production of molecular memory devices.
专利号:US-10919904-B2 优先权日:2016-08-17 标 题 :Northern-southern route to synthesis of bacteriochlorins 发明人:LIU YIZHOU; LINDSEY JONATHAN S; ALLU SRINIVASA RAO; FUJITA HIKARU 权利人:UNIV NORTH CAROLINA STATE 摘要:Described herein are chlorins, bacteriochlorins, methods and intermediates for the synthesis of bacteriochlorins, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as luminescent compounds in flow cytometry, and as active agents in photodynamic therapy (PDT).
专利号:US-3872101-A 优先权日:1969-04-11 标题:Synthesis of {60 , {62 -unsaturated compounds 发明人:SIDDALL JOHN E; FRIED JOHN H 权利人:ZOECON CORP 摘要:Stereospecific synthesis of Alpha , Beta -ethylenically unsaturated compounds by the reaction of an organo-copper or organo-manganese reagent with an Alpha , Beta -acetylenically unsaturated compound at a temperature of -40*C or less.
专利号:WO-2009115333-A1 优先权日:2008-03-20 标 题:Novel synthesis of praziquantel 发明人:DOEMLING ALEXANDER 权利人:DOEMLING ALEXANDER 摘要:The present invention discloses a novel and efficient synthesis of praziquantel (I).
[参考文献]: Juyoung Lee, Et Al. In Vitro Metabolic Conversion Of The Organic Breakdown Products Of Glucosinolate To Goitrogenic Thiocyanate Anion. J Sci Food Agric. 2015 Aug 30;95(11):2244-51.
合成参考文献
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