CAS: 645-59-0; 3-Phenylpropionitrile

该化合物是配有公式C9H9N的有机化合物,其组成为联苯组,附于一种丙烯酰胺,这种芳烃硝酸盐通常用作有机合成的中间体,特别是在生产药品,农用化学品和特殊化学品方面,其主要优点包括硝基功能组的高度反应性,能够进行多种变异,如水解,减量或核丙基生物添加.该化合物在标准条件下具有良好稳定性,在普通有机溶剂中可溶解,便于在多种反应系统中使用,其结构灵活性对于在精细的化学制造中建立复杂的分子框架很有价值.

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CAS号1885-38-7 肉桂腈 | CAS号4360-47-8 3-苯基丙烯腈 | CAS号1197-50-8 (NE)-N-(3-pheny... | CAS号2038-57-5 3-苯基丙基胺 | CAS号22767-95-9 Benzenepropanoi... | CAS号170646-96-5 N-甲氧基-N-甲基-3-苯基-丙酰胺 | CAS号2021-28-5 3-苯丙酸乙酯 | CAS号501-52-0 3-苯丙酸 | CAS号107-13-1 丙烯腈 | CAS号98-80-6 苯硼酸 | CAS号108664-49-9 2-benzyl-1-thio... | CAS号60-82-2 根皮素 | CAS号103-25-3 3-苯丙酸甲酯 | CAS号104-53-0 3-苯丙醛 | CAS号501-52-0 3-苯丙酸 | CAS号102-93-2 3-苯基丙酰胺 | CAS号1083-30-3 1,3-二苯基丙-1-酮 | CAS号2021-28-5 3-苯丙酸乙酯 | CAS号29898-25-7 1-苯基-3-己酮 | CAS号64920-29-2 2-氧代-基丁酸乙酯

合成工艺路线路线简述

    📜(肉)桂腈置于氢气体系中,用 1,4-二氧六环 作为反应溶剂,化学反应 20.0H,以91%的收率获得产物苯代丙腈
    参考文献:羟基磷灰石上铑纳米粒子上硝基芳烃和烯烃的选择性加氢
    标题:羟基磷灰石上铑纳米粒子上硝基芳烃和烯烃的选择性加氢
    摘要:我们已经展示了一种高活性和选择性的纳米催化剂rh / Hap(负载在羟基磷灰石上的铑),用于在肼的条件下用肼还原硝基芳烃,以及在温和条件下用氢气将烯烃氢化.用肼作为还原剂,在rh / Hap催化剂上,将硝基芳烃选择性地氢化成相应的苯胺,并还原未还原的基团,如卤化物(氟,氯,溴和碘),氰基和烯烃.而且,当使用h 2时,在存在可还原的硝基,羰基和氰基的情况下,在rh / Hap催化剂上,烯烃可以高产率选择性地氢化成相应的烷烃.
    DOI:10.1002/adsc.201200330

    海关参考信息

    专利信息


    专利号:US-11999757-B2
    优先权日:2017-11-01
    标 题:Synthesis of boronate ester derivatives and uses thereof
    发明人:BOYER SERGE HENRI; HECKER SCOTT J; VERZIJL GERARDUS K M; HERMSEN PETRUS J
    权利人:MELINTA SUBSIDIARY CORP
    摘要:Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.

    专利号:US-10669292-B2
    优先权日:2014-05-05
    标 题 :Synthesis of boronate salts and uses thereof
    发明人:HECKER SCOTT; BOYER SERGE
    权利人:REMPEX PHARMACEUTICALS INC
    摘要:Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.

    专利号:US-8618281-B2
    优先权日:2006-01-03
    标 题 :Geometric synthesis of porphyrin rods
    发明人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D
    权利人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D; UNIV NORTH CAROLINA STATE
    摘要:A method of making a compound of Formula I′ n ncomprises reacting a compound of the formula DLCHO, with a compound of the formulan n nto produce the compound of Formula I′. Methods of using the compounds are also described, particularly as intermediates for the synthesis of porphyrin rods, which porphyrin rods are in turn useful for (among other things) the production of molecular memory devices.

    专利号:US-10919904-B2
    优先权日:2016-08-17
    标 题 :Northern-southern route to synthesis of bacteriochlorins
    发明人:LIU YIZHOU; LINDSEY JONATHAN S; ALLU SRINIVASA RAO; FUJITA HIKARU
    权利人:UNIV NORTH CAROLINA STATE
    摘要:Described herein are chlorins, bacteriochlorins, methods and intermediates for the synthesis of bacteriochlorins, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as luminescent compounds in flow cytometry, and as active agents in photodynamic therapy (PDT).

    专利号:US-3872101-A
    优先权日:1969-04-11
    标题:Synthesis of {60 , {62 -unsaturated compounds
    发明人:SIDDALL JOHN E; FRIED JOHN H
    权利人:ZOECON CORP
    摘要:Stereospecific synthesis of Alpha , Beta -ethylenically unsaturated compounds by the reaction of an organo-copper or organo-manganese reagent with an Alpha , Beta -acetylenically unsaturated compound at a temperature of -40*C or less.

    专利号:WO-2009115333-A1
    优先权日:2008-03-20
    标 题:Novel synthesis of praziquantel
    发明人:DOEMLING ALEXANDER
    权利人:DOEMLING ALEXANDER
    摘要:The present invention discloses a novel and efficient synthesis of praziquantel (I).

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Juyoung Lee, Et Al. In Vitro Metabolic Conversion Of The Organic Breakdown Products Of Glucosinolate To Goitrogenic Thiocyanate Anion. J Sci Food Agric. 2015 Aug 30;95(11):2244-51.

    合成参考文献


    摘要:Chciuk, T. V.; Flowers, R. A.; Flowers, R. A., Science of Synthesis Knowledge Updates, (2016) 2, 232.
    摘要:Champagne, P. A.; Drouin, M.; Paquin, J.-F., Science of Synthesis Knowledge Updates, (2016) 1, 425.
    摘要:Kawęcki, R., Science of Synthesis Knowledge Updates, (2011) 3, 234.
    摘要:Jie, X.; Su, W., Science of Synthesis, (2022) , 19.
    摘要:van Leeuwen, P. W. N. M., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 451.
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