专利号:US-6492524-B1 优先权日:2001-03-27 标 题 :Process for the synthesis of an aryl pyridine base using a zeolite catalyst 发明人:KULKARNI SHIVANAND JANARDAN; RAGHAVAN KONDAPURAM VIJAYA; NAGABANDI SRINIVAS; VIPPAGUNTA RADHA RANI 权利人:COUNCIL SCIENT IND RES 摘要:The present invention provides an improved process for the synthesis of aryl pyridine bases by reacting an aromatic aldehyde or ketone and allylic alcohol or aldehyde in presence of ammonia in gas phase, in high yield and selectivity with catalyst obtained by optionally modifying a zeolite having an atomic ratio of Si to Al, 2.5 to 12.5 and /or with at least one metal ion and/or metal compound selected from the group consisting of lead and lanthanum. This process provides an eco-friendly, more economical and highly selective heterogeneous method.
专利号:US-8207337-B2 优先权日:2007-01-29 标 题:Reagent for organic synthesis reaction containing organic triol borate salt 发明人:MIYAURA NORIO; YAMAMOTO YASUNORI 权利人:MIYAURA NORIO; YAMAMOTO YASUNORI; WAKO PURE CHEM IND LTD 摘要:[Problem] n To provide an organoboron compound-containing reagent for organic synthesis reactions which undergoes no trimerization with dehydration, does not necessitate activation with a base, and is stable and highly active. n [Means for Solving Problems] n The reagent for organic synthesis reactions contains an organic triol borate salt represented by any of the general formulae (I) to (III) and general formula (XVI): (wherein R 1 represents alkyl, alkenyl, etc.; R 2 represents optionally substituted alkyl, alkenyl, alkynyl, etc. or represents hydrogen; m + represents an alkaline metal ion, phosphonium ion, or given ammonium ion; M 2+ represents an alkaline earth metal; X represents halogen or alkoxide; Y represents an alkali metal ion, etc.; A represents optionally substituted methylene; and n represents an integer).
专利号:US-11612873-B2 优先权日:2017-05-31 标 题:Homopolymer encoded nucleic acid memory 发明人:EFCAVITCH J WILLIAM; AGARWALLA SANJAY; ALBIZATI Kim; GRUBBS ALAN W; HOLDEN MATTHEW T; HOPKINS PATRYCJA A; SINGH JAY K 权利人:MOLECULAR ASSEMBLIES INC 摘要:Nucleic acid memory strands encoding digital data using a sequence of homopolymer tracts of repeated nucleotides provides a cheaper and faster alternative to conventional digital DNA storage techniques. The use of homopolymer tracts allows for lower fidelity, high throughput sequencing techniques such as nanopore sequencing to read data encoded in the memory strands. Specialized synthesis techniques allow for synthesis of long memory strands capable of encoding large volumes of data despite the reduced data density afforded by homopolymer tracts as compared to conventional single nucleotide sequences.
专利号:US-2020384451-A1 优先权日:2017-09-05 标题:Phosphine free cobalt based catalyst, process for preparation and use thereof 发明人:BALARAMAN EKAMBARAM; MIDYA SIBA PRASAD; LANDGE VINOD GOKULKRISHNA 权利人:COUNCIL SCIENT IND RES 摘要:The present invention discloses a phosphine free cobalt based catalyst of formula (I) and a process for preparation thereof. The present invention further discloses a process for the synthesis of aromatic heterocyclic compounds of formula (II) and pyrazine derivative using the phosphine free cobalt based catalyst of formula (I).
专利号:EP-1373209-B1 优先权日:2001-03-30 标 题 :A process for the synthesis of an aryl pyridine base using a zeolite catalyst 发明人:KULKARNI SHIVANAND JANARDAN; RAGHAVAN KONDAPURAM VIJAYA; NAGABANDI SRINIVAS; VIPPAGUNTA RADHA RANI 权利人:COUNCIL SCIENT IND RES
专利号:WO-2025123046-A1 优先权日:2023-12-07 标 题:Synthesis of leucine-rich repeat kinase 2 modulators 发明人:STORZ THOMAS; DONG HANQING; CHEN CHUNGPIN HERMAN 权利人:ARVINAS OPERATIONS INC 摘要:Provided are methods for synthesizing compounds having activity against Leucine- rich repeat kinase 2 (LRRK2), as well as intermediates generated during said methods.