CAS: 13472-61-2; 5-Iodo-2-Methoxypyridine

相似化合物

902837-52-9 112197-15-6 13472-79-2

上下游产品

2-choro-5-iodopyridine methyl iodide 2-aminopyridine 2-amino-5-iodopyridine 5-(benzyloxy)-2-methoxypyridine 2-(6-methoxy-pyridin-3-yl)-malonic acid diethyl ester 3,4-diphenyl-hexane

📜2-甲氧基吡啶置于n-溴代丁二酰亚胺(Nbs),正丁基锂,异丙基氯化镁体系中,用 四氢呋喃,正己烷,乙腈 用作溶剂,化学反应 20.75H,反应生成5-碘-2-甲氧基吡啶
参考文献:二丁基(异丙基)镁酸锂(1-)和氯化锂通过卤素-镁交换进行非低温合成功能化的2-甲氧基吡啶
标题:二丁基(异丙基)镁酸锂(1-)和氯化锂通过卤素-镁交换进行非低温合成功能化的2-甲氧基吡啶
摘要:使用二丁基(异丙基)镁酸锂(1-)和相应的溴或碘类似物制备在3-,5-或6-位官能化的2-甲氧基吡啶和在3-位官能化的2,6-二甲氧基吡啶.非低温条件下的氯化锂.根据在两种镁酸盐之间的选择以及反应介质中氯化锂的存在与否,对程序进行了优化. 吡啶-镁-锂-有机金属试剂
Doi:10.1055/s-0031-1289687

专利信息

专利号:WO-2024185814-A1
优先权日:2023-03-06
标题:Method for producing aryl compound containing tritylsulfanyl group
发明人：OKAZOE TAKASHI; NOZAKI KYOKO; GATZENMEIER Tim; LIU YUE
权利人:AGC INC; UNIV TOKYO
摘要:The present invention provides: a substrate for achieving the highly efficient synthesis of an aryl compound containing a tritylsulfanyl group; a method for producing a compound containing an SF 5 group using the substrate; and others. The present invention is a method for producing an aryl compound containing a tritylsulfanyl group, the method comprising thiotritylating a halogenated aryl compound represented by general formula (1) [wherein A 1 represents an aryl group that may have a substituent or a heteroaryl group that may have a substituent; and X represents a halogen atom] using [(triphenylmethyl)sulfanyl]potassium or [(triphenylmethyl)sulfanyl]sodium to produce an aryl compound containing a tritylsulfanyl group, the aryl compound being represented by general formula (2) [wherein A 1 is the same as A 1 in general formula (1); and Ph represents a phenyl group].