CAS: 10070-92-5; Pyrimidine-5-Carbaldehyde

相似化合物

25193-95-7 4595-61-3 34253-01-5

上下游产品

CAS号4595-59-9 5-溴嘧啶 | CAS号109-94-4 甲酸乙酯 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号541-41-3 氯甲酸乙酯 | CAS号626-55-1 3-溴吡啶 | CAS号497-19-8 纯碱 | CAS号496-13-9 2,3-二氢-1H-吡咯[3,... | CAS号147740-04-3 2,3-二氢-1H-吡咯[3,... | CAS号79691-74-0 1-(嘧啶-5-基)乙醇 | CAS号10325-70-9 5-乙酰基嘧啶 | CAS号101346-02-5 5-氯甲基嘧啶 | CAS号25193-95-7 5-嘧啶甲醇 | CAS号287472-26-8 3-chloro-4-pyri... | CAS号647860-02-4 3-methylsulfany... | CAS号647860-03-5 3-ethylsulfanyl... | CAS号647860-04-6 3-prop-2-enylsu...

甲酸乙酯置于正丁基锂,盐酸体系中,用 四氢呋喃,乙醚 用作溶剂,化学反应 2.5H,反应生成嘧啶-5-甲醛
参考文献:6-O-Substituted Erythromycin Derivatives Having Improved Gastrointestinal Tolerance
标题:6-O-Substituted Erythromycin Derivatives Having Improved Gastrointestinal Tolerance
摘要:具有化学式(i)的化合物可用于治疗细菌感染,同时避免胃肠不耐受的风险.含有这些化合物的组合物以及使用这些化合物进行治疗的方法也被揭示.

专利信息

专利号:US-11629150-B2
优先权日:2016-07-01
标题:Synthesis of N-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines
发明人：SMITH ALEXANDER; WHITE HANNAH S; TAVARES FRANCIS XAVIER; KRASUTSKY SERGIY; CHEN JIAN-XIE; DORROW ROBERTA L; ZHONG HUA
权利人:G1 THERAPEUTICS INC
摘要:This invention is in the area of synthesizing pyrimidine-based compounds useful in the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.

专利号:WO-2025128848-A1
优先权日:2023-12-12
标题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula (I), useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I).

专利号:US-8138272-B2
优先权日:2006-05-22
标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
发明人：KONRADI ANDREI W; SMITH JENIFER L
权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobu†or related reaction conditions.

专利号:US-6764842-B2
优先权日:2001-03-28
标题 :Enantioselective bioreduction for the preparation of integrin receptor antagonist intermediates
发明人：STURR MICHAEL G; BOYD RUSSELL FIELDON; GBEWONYO KODZO; NTI-GYABAAH JOSEPH; POLLARD DAVID J; MCWILLIAMS JAMES CHRISTOPHER; TELARI KATHLEEN A
权利人:MERCK & CO INC
摘要:The present invention relates to a novel enantioselective bioreduction using a yeast microorganism for the preparation of the chiral allylic alcohols of structural formula I (R is hydrogen or methyl) which are useful in the asymmetric synthesis of integrin αvβ 3 receptor antagonists.

专利号:WO-2025125811-A1
优先权日:2023-12-12
标题:Heterocyclic compounds and their use for the treatment of neurological disorders
发明人：PLOWRIGHT ALLEYN THOMAS; PFEIFFER THOMAS; MÄRCHER-RØRSTED EMIL; DUCKWORTH EDWARD JOSEPH
权利人:ONTRACK THERAPEUTICS LTD
摘要:The present invention relates to novel synthetic compounds of Formula (I) and (II) related to naturally occurring flavonoids such as 7,8-dihydroxyflavone (7,8-DHF). The invention further relates to the method of synthesis, the use of these compounds as research tools and their use as pharmaceuticals.

专利号:CN-109789142-A
优先权日:2016-07-01
标题 :Synthesis of N- (heteroaryl) -pyrrolo [3,2-D ] pyrimidin-2-amines