CAS: 91722-21-3; 3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl 9-((5-Hydroxy-6-(Hydroxymethyl)-3,4-Bis((3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Tetrahydro-2H-Pyran-2-yl)Oxy)-4,11B-Dimethyl-8-Methylenetetradecahydro-6A,9-Methanocyclohepta[a]Naphthalene-4-Carboxylate

专利信息

专利号:US-10040752-B2
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
发明人：MKRTCHYAN GNEL; YAO QINGWEI
权利人:CODY LABORATORIES INC
摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

专利号:US-10533205-B1
优先权日:2013-10-09
标 题:Kaurenoic acid glycoside precursors and methods of synthesis
发明人：ZIPP BRANDON
权利人:VITALITY BIOPHARMA INC
摘要:Ent-kaurenoic acid glycoside precursor compositions and synthesis methods are provided. The KA-19-monoside, KA-19-bioside and KA-19-trioside precursors can be used as starting materials for a variety of kaurenoic acid based reactions. The precursors provide alternative synthesis pathways for steviol glycosides to the natural pathway based on Steviol biosynthesis. The alternative synthesis pathways using the precursors also circumvent the rate limiting step of the natural Steviol biosynthesis pathway. The precursors can be used individually or in combination to produce a mixture or individual steviol glycosides such as Rebaudioside A, Rebaudioside D or Rebaudioside M. Control over the precursor quantities and composition allows control over the composition of the resulting steviol glycosides that are finally produced.

专利号:WO-2014051357-A1
优先权日:2012-09-28
标 题 :Composition for improving skin elasticity and wrinkles
发明人：KIM HYO JIN; LEE SANG HWA; RYU JONG SEONG
权利人:LG HOUSEHOLD & HEALTH CARE LTD
摘要:The present invention relates to a composition for improving skin elasticity and wrinkles. More particularly, the present invention relates to a collagen synthesis facilitator, to a cosmetic composition, to a pharmaceutical composition, and to a food composition which facilitate the collagen synthesis of fibroblasts and have excellent effects in improving skin elasticity and reducing wrinkles. Also, the present invention relates to a method for improving skin elasticity and preventing, reducing, or treating skin wrinkles by using the composition.

专利号:US-12071646-B2
优先权日:2014-09-11
标 题 :Cells comprising mogroside pathway enzymes and uses thereof
发明人：ITKIN MAXIM; DAVIDOVICH-RIKANATI RACHEL; COHEN SHAHAR; PORTNOY VITALY; DORON-FAIGENBOIM ADI; PETREIKOV MARINA; SHEN SHMUEL; TADMOR YAAKOV; BURGER YOSEF; LEWINSOHN EFRAIM; KATZIR NURIT; SCHAFFER ARTHUR A; OREN ELAD
权利人:THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO
摘要:Isolated mogroside and mogrol biosynthetic pathway enzyme polypeptides useful in mogroside biosynthesis are provided. Mogroside biosynthetic pathway enzymes of the invention include squalene epoxidase (SE), epoxy hydratase (EH), cytochrome p450 (Cyp), cucurbitadienol synthase (CDS) and udp-glucosyl-transferase (UGT), Also provided are methods of producing a mogroside using the isolated mogroside and mogrol biosynthetic enzyme polypeptides, the methods comprising contacting a mogrol and/or a glycosylated mogrol (mogroside) with at least one UDP glucose glucosyl transferase (UGT) enzyme polypeptide of the invention catalyzing glucosylation of the mogrol and/or the glucosylated mogrol to produce a mogroside with an additional glucosyl moietie(s), thereby producing the mogroside. Alternatively or additionally provided is a method of synthesizing a mogrol, the method comprising contacting a mogrol precursor substrate with one or more mogrol biosynthetic pathway enzyme polypeptides as described herein catalyzing mogrol synthesis from the mogrol precursor substrate, thereby synthesizing the mogrol.

专利号:US-2024287479-A1
优先权日:2021-08-23
标 题 :Glycosyltransferase mutant, and method for catalytic synthesis of rebaudioside m using glycosyltransferase mutant

专利号:CN-113862319-A
优先权日:2021-09-16
标 题 :Application of ginseng glycosyltransferase in the synthesis of stevia