CAS: 6555-40-4; Ethyl 2-Hydroxy-6-Methylbenzoate

上下游产品

CAS号6520-83-8 2-甲氧基-6-甲基苯甲酸乙酯 | CAS号123-73-9 2-丁烯醛 | CAS号609-15-4 2-氯乙酰乙酸乙酯 | CAS号3419-32-7 6-甲基-2-氧代-3-环己烯... | CAS号87-24-1 邻甲基苯甲酸乙酯 | CAS号141-97-9 乙酰乙酸乙酯 | CAS号113704-19-1 ethyl (E)-2-chl... | CAS号1801-77-0 二氯乙氧基合氧钒 | CAS号113704-23-7 ethyl 2-chloro-... | CAS号64-17-5 乙醇 | CAS号109987-14-6 ethyl 2-acetylo... | CAS号29922-52-9 2-(羟甲基)-3-甲基苯酚 | CAS号6520-83-8 2-甲氧基-6-甲基苯甲酸乙酯 | CAS号567-61-3 2-羟基-6-甲基苯甲酸 | CAS号33528-09-5 2-羟基-6-甲基苯甲酸甲酯 | CAS号6161-65-5 2-甲氧基-6-甲基苯甲酸 | CAS号16611-84-0 Anacardic Acid | CAS号74794-52-8 1H-2-Benzopyran... | CAS号50463-84-8 2-甲氧基-6-甲基苯甲酰氯 | CAS号394223-70-2 2-(甲氧基甲氧基)-6-甲基苯甲酸乙酯

邻甲基苯甲酸乙酯置于dipotassium Peroxodisulfate,[ruthenium(II)(η6-1-Methyl-4-Isopropyl-Benzene)(Chloride)(μ-Chloride)]2,三氟乙酸,三氟乙酸酐体系中,化学反应 11.0H,以66%的收率获得产物6-甲基水杨酸乙酯/2-羟基-6-甲基苯甲酸乙酯
参考文献:Ruthenium(II)-Catalyzed Synthesis Of Hydroxylated Arenes With Ester As An Effective Directing Group
标题:Ruthenium(II)-Catalyzed Synthesis Of Hydroxylated Arenes With Ester As An Effective Directing Group
摘要:An Unprecedented Ru(II) Catalyzed Ortho-Hydroxylation Has Been Developed For The Facile Synthesis Of A Variety Of Multifunctionalized Arenes From Easily Accessible Ethyl Benzoates With Ester As An Efficient Directing Group. Both The Tfa/tfaa Cosolvent System And Oxidants Serve As The Critical Success Factors In This Transformation. The Reaction Demonstrates Excellent Reactivity,Good Functional Group Tolerance,And High Yields.
DOI:10.1021/ol301104N

专利信息

专利号:EP-1368298-B1
优先权日:2000-12-23
标 题:Process for the preparation of 5- and/or 6 - substituted - 2 - hydroxy-benzoic acid esters
发明人：PFRENGLE ANDREAS; SCHEFFER ROBERT J H; SCHEIBLICH STEFAN DR; WEVERS JAN HENDRIK; VOGELBACHER UWE JOSEF; DOEHNER ROBERT F
权利人:BASF AG
摘要:There is provided a single-step process for the preparation of a compound of formula (I). Compounds of formula (I) are useful as starting materials in the synthesis of natural products and in the manufacture of benzo-phenone fungicidal agents.

专利号:US-6441219-B1
优先权日:1999-07-15
标 题 :Process for the preparation of 5-and/or 6-substituted-2-hydroxybenzoic acid esters
发明人：DOEHNER JR ROBERT FRANCIS
权利人:BASF CORP
摘要:There is provided a single-step process for the preparation of a compound of formula I. n Compounds of formula I are useful as starting materials in the synthesis of natural products and in the manufacture of benzophenone fungicidal agents.

专利号:US-6559336-B2
优先权日:1999-07-15
标 题:Process for the preparation of 5- and/or 6-substituted-2-hydroxybenzoic acid esters
发明人：PFRENGLE ANDREAS; SCHEFFER ROBERT J H; SCHEIBLICH STEFAN; WEVERS JAN HENDRIK; VOGELBACHER UWE JOSEF; DOEHNER ROBERT F
权利人:BASF AG
摘要:There is provided a single-step process for the preparation of a compound of formula I.Compounds of formula I are useful as starting materials in the synthesis of natural products and in the manufacture of benzophenone fungicidal agents.

专利号:US-9168248-B2
优先权日:2009-02-17
标 题:Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase
发明人：LACHANCE NICOLAS; LECLERC JEAN-PHILIPPE; LI CHUN SING; MORADEI OSCAR MIGUEL
权利人:LACHANCE NICOLAS; LECLERC JEAN-PHILIPPE; LI CHUN SING; MORADEI OSCAR MIGUEL; MERCK CANADA INC
摘要:Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.

专利号:US-11286270-B2
优先权日:2017-10-11
标 题:Boronic acid derivatives and synthesis thereof
发明人：HECKER SCOTT J; BOYER SERGE HENRI; DIELEMANS HUBERTUS J A; GONZALEZ DE CASTRO ANGELA; DE VRIES ANDREAS H M; LEFORT LAURENT
权利人:QPEX BIOPHARMA INC
摘要:Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, β-lactamase inhibitors (BLIs).

专利号:WO-9314086-A1
优先权日:1992-01-17
标 题 :Substituted 1-isoquinolone derivatives as angiotensin ii antagonists
发明人：FISHER LAWRENCE E; CAROON JOAN M; STABLER STEPHEN R; CLARK ROBIN D
权利人:SYNTEX INC
摘要:1-Isoquinolone derivatives and related compounds according to formula (I) wherein, Y is selected from the group consisting of H, OH, lower alkoxy, and halo; X is selected from the group consisting of H, lower alkyl acid, lower alkyl ester, and lower alkyl; and R1 is selected from the group consisting of H, alkenyl, lower alkyl, lower cycloalkyl, unsubstituted or substituted 3-spiro-1H-indane of structure (II) wherein R2 is H, OH, lower alkyl, lower alkoxy or halo, and 3-spiro-cycloalkyl of structure (III) wherein n is an integer from zero to six, provided that when R1 is spiro- X is H, or a pharmaceutically acceptable salt thereof, with the proviso that when R1 is spiro-, X is H, and when R1 is H, alkenyl, lower alkyl or lower cycloalkyl substituted at the 3-position of the isoquinolone moiety and X is H or lower alkyl, the (2'-1H--tetrazol-5-yl)biphenyl-4'-ylmethyl group cannot be at the 2(N) position, are useful as angiotensin II receptor antagonists. Also disclosed are methods of synthesis, intermediates, pharmaceutical formulations and methods of treatment.