CAS: 639-58-7; Triphenyltin Chloride

该化合物是有机合成和催化中广泛使用的有机锡化合物,其主要优点包括它作为静态联动反应的多用途中间体的作用,能够以高选择性和效率形成碳-碳联系;该化合物在标准条件下具有良好稳定性,便于处理和储存;其联苯组增强了交叉反应的回弹性,而氯离子体允许进一步功能化;氯三联苯丁nane也被用于聚合物稳定,并成为其他有机锡衍生物的前体;适当的安全措施由于其毒性和潜在的环境影响而必不可少.

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合成工艺路线路线简述

  • 合成目标产物 Chlorotriphenyltin 主要起始原料 Diphenyltin Dichloride
  • (文献来源)合成步骤主要原料 Diphenyltin Dichloride
二苯基二氯化锡 以 四氢呋喃,氯仿 作为反应溶剂,化学反应生成 三苯基氯化锡
参考文献:Vinyl Derivatives Of The Metals. Ii. The Cleavage Of Vinyltin Compounds By The Halogens And By Protonic Acids1
标题:Vinyl Derivatives Of The Metals. Ii. The Cleavage Of Vinyltin Compounds By The Halogens And By Protonic Acids1
摘要:
DOI:10.1021/ja01566A027

海关参考信息

专利信息


专利号:US-4762935-A
优先权日:1986-10-06
标题:Precursors and synthesis of methyl-9-oxo-11α,16-dihydroxy-16-vinyl-5-cis-13-trans-prostadienoates
发明人:WISSNER ALLAN; GREEN KENNETH E; HAMANN PHILIP R; LEVIN JEREMY
权利人:AMERICAN CYANAMID CO
摘要:This disclosure describes novel compounds which are useful as precursors in the synthesis of 9-oxo-11α,16-dihydroxy-16-vinyl-5-cis-13-trans-prostadienoate esters which possess activity as hypotensive agents and/or as vasodilators.

专利号:US-12102991-B2
优先权日:2019-07-17
标题:Ligand-directed reticular synthesis of metal-organic frameworks having edge-transitive ALB network topologies
发明人:FARHA OMAR K; CHEN ZHIJIE; LI PENGHAO; STODDART J FRASER
权利人:UNIV NORTHWESTERN
摘要:A series of isoreticular metal-organic frameworks composed of metal nodes connected by rigid trigonal prismatic organic linkers and having a 6,12-coordinatled alb network topology are provided. Also provided are methods of synthesizing the metal-organic frameworks and methods of using the metal-organic frameworks to catalyze the hydrolysis of organic molecules, such as nerve agents, having hydrolysable bonds.

专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:US-4705866-A
优先权日:1985-12-26
标 题 :Synthesis of N-halogenated phenyl maleimide compounds with tin containing catalysts
发明人:GASTINGER ROBERT G
权利人:ATLANTIC RICHFIELD CO
摘要:A process for the preparation of N-brominated or N-chlorinated phenylmaleimide by reacting maleic anhydride and a brominated or chlorinated aniline compound at temperatures of from about 100 DEG C. to about 210 DEG C. in the presence of tin containing catalyst compound and optionally an inert solvent.

专利号:US-11384044-B2
优先权日:2017-08-03
标 题 :Method for introducing substituent into α,β-unsaturated ketone and method for synthesizing prostaglandin using the same
发明人:SUZUKI MASAAKI; KOYAMA HIROKO
权利人:NAT CT GERIATRICS & GERONTOLOGY
摘要:The present invention provides a method for introducing substituents into the α-position and the β-position of an α,β-unsaturated ketone, which not only can be used for the synthesis of a prostaglandin by a three-component coupling process, but also enables synthesis of a prostaglandin in a high yield by one-pot operation without requiring the use of a large excess amount of any of the three components required for the synthesis or using a highly toxic heavy metal as a catalyst or a solvent that is highly toxic to living bodies, and a method for synthesizing a prostaglandin using the same technical means. n The method for introducing substituents into an α,β-unsaturated ketone according to the present invention is a method for introducing substituents into the carbon at the α-position and the carbon at the β-position of an α,β-unsaturated ketone, including: a first step of mixing alkyllithium and trialkylalkenyl tin in which tin atom binds to the vinyl position of the alkenyl group; a second step of mixing the mixture of the first step and dialkylzinc; a third step of mixing the mixture of the second step and an α,β-unsaturated ketone; and a fourth step of mixing the mixture of the third step and a trifluoromethanesulfonate compound.

专利号:US-9968097-B2
优先权日:2012-05-30
标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction
发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
权利人:BAYER CROPSCIENCE AG
摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
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主要参考文献

[参考文献]: Corwin Hansch, Et Al. Larvicidal Activities Of Some Organotin Compounds On Mosquito Larvae: A Qsar Study. Eur J Med Chem. 2009 Jan;44(1):260-73.
[参考文献]: Flaviana T Vieira, Et Al. Synthesis, Characterization And Biocidal Activity Of New Organotin Complexes Of 2-(3-Oxocyclohex-1-Enyl)Benzoic Acid. Eur J Med Chem. 2010 Mar;45(3):883-9.
[参考文献]: Guo-Lan Huang, Et Al. Immobilization Of Spirulina Subsalsa For Removal Of Triphenyltin From Water. Artif Cells Blood Substit Immobil Biotechnol. 2002 Jul;30(4):293-305.
[参考文献]: Janina Gabrielska, Et Al. Antioxidative Effect Of Quercetin And Its Equimolar Mixtures With Phenyltin Compounds On Liposome Membranes. J Agric Food Chem. 2006 Oct 4;54(20):7735-46.
[参考文献]: Jérme Darrouzès, Et Al. New Approach Of Solid-Phase Microextraction Improving The Extraction Yield Of Butyl And Phenyltin Compounds By Combining The Effects Of Pressure And Type Of Agitation. J Chromatogr A. 2005 Apr 22;1072(1):19-27.

合成参考文献


参考文献:10.1007/s10646-011-0739-5
摘要:Antizar-Ladislao B, Sarkar SK, Anderson P, Peshkur T, Bhattacharya BD, Chatterjee M, Satpathy KK. Baseline of butyltin contamination in sediments of Sundarban mangrove wetland and adjacent coastal regions, India. Ecotoxicology. 2011 Nov;20(8):1975–83. doi: 10.1007/s10646-011-0739-5.
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