CAS: 6295-06-3; Butyl 2-Oxoacetate

该化合物是属于该类丙氧酸的有机化合物,其特征是其酯性功能组,由丁醇和羟基酸反应形成.该化合物一般是无色的,是具有特质气味的浅黄色液体,在有机溶剂中溶解,溶解水量有限.丁基羟基以其活性为名,特别是在凝聚反应中,使其在各种化学合成中有用,包括制药和农用化学品的生产.此外,它可以作为合成更复杂的分子的建筑块.安全数据表明,应谨慎处理,因为它可能会对皮肤和眼睛产生刺激.建议在一个冷,干燥的地方妥善储存,远离不相容的材料,以保持其稳定性并防止降解.

结构式图片

上下游产品

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合成工艺路线路线简述

    📜马来酸二丁酯 反应生成 乙醛酸正丁酯
    参考文献:Notes-A Convenient Method For Reduction Of Hydroperoxide Ozonation Products
    标题:Notes-A Convenient Method For Reduction Of Hydroperoxide Ozonation Products
    摘要:
    DOI:10.1021/jo01076A044

    海关参考信息

    专利信息


    专利号:WO-2014097257-A1
    优先权日:2012-12-21
    标 题:A method of preparation of (1'r,3r,4r)-4-acetoxy-3-(1'-(tert-butyldimethylsilyloxy)ethyl)-2-azetidinone, a precursor for carbapenem antibiotics synthesis
    发明人:GRZESZCZYK BARBARA; STECKO SEBASTIAN; FURMAN BARTÅ?OMIEJ; CHMIELEWSKI MAREK
    权利人:INST CHEMII ORGANICZNEJ PAN
    摘要:The subject of the present invention is a method of preparation of (1'R,3R,4R)-4-acetoxy-3-(1'- (tert-butyl-dimethylsilyloxy)ethyl)-2-azetidinone defined by the formula (1) which is a basic chiral building block in the synthesis of carbapenem antibiotics.

    专利号:US-10266467-B2
    优先权日:2017-08-02
    标 题:Synthesis of glycols via transfer hydrogenation of alpha-functional esters with alcohols
    发明人:CHAKRABORTY SUMIT; HEMBRE ROBERT THOMAS
    权利人:EASTMAN CHEM CO
    摘要:A transfer hydrogenation process for forming vicinal diols by hydrogenating 1,2-dioxygenated organic compounds using alcohols as the reducing agent instead of the traditional H 2 gas. The transfer hydrogenation is carried out under milder conditions of temperature and pressure than is typical for ester hydrogenation with H 2 . The milder conditions of operation provide benefits, such as lower operating and capital costs for industrial scale production as well as savings in product purification due to the avoidance of by-products from exposure of reaction mixtures and products to high temperatures.

    专利号:US-4536334-A
    优先权日:1979-06-28
    标题 :Preparation of β-lactam derivatives
    发明人:SUNAGAWA MAKOTO; MATSUMURA HARUKI; INOUE TAKAAKI; HIROHASHI TOSHIYUKI
    权利人:SUMITOMO CHEMICAL CO
    摘要:A process for preparing a β-lactam derivative having a hydrogen atom on the nitrogen atom of the β-lactam ring, which comprises reacting a β-lactam derivative having a mono- or diarylmethyl group on the nitrogen atom of the β-lactam ring with an acid or ceric ammonium nitrate to cleave the bond between the nitrogen atom and the mono- or diarylmethyl group; and novel β-lactam derivatives useful as intermediates for the synthesis of pharmaceutical agents.

    专利号:US-11225655-B2
    优先权日:2010-04-16
    标题:Bi-functional complexes and methods for making and using such complexes
    发明人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
    权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
    摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

    专利号:US-2019039978-A1
    优先权日:2017-08-02
    标 题:Synthesis of glycols via transfer hydrogenation of alpha-functional esters with alcohols

    专利号:EP-1607389-A1
    优先权日:1999-09-10
    标题:4-protected-amino-2-substituted-1,2,3,4-tetrahydroquinolines as intermediates for CETP inhibitors
    发明人:DENINNO MICHAEL PAUL; MAGNUS-ARYITEY GEORGE TETTEH; RUGGERI ROGER BENJAMIN; WESTER RONALD THURE
    权利人:PFIZER PROD INC
    摘要:The present invention relates to compounds of formulan nwherein P 2 , R 2 , R 5 , R 6 , R 7 and R 8 are as defined herein, which are useful as intermediates innthe synthesis of 4-carboxyarnino-2-substitated-1,2,3,4-tetrahydroquinolines.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Chemla, F.; Ferreira, F.; Pérez-Luna, A., Science of Synthesis Knowledge Updates, (2012) 1, 469.
    摘要:Terada, M., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 321.
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