CAS: 5858-28-6; 5-Methyl-2-Nitrobenzaldehyde

上下游产品

CAS号66424-92-8 5-甲基-2-硝基苄醇 | CAS号79-37-8 草酰氯 | CAS号65152-29-6 (5-methyl-2-nit... | CAS号109467-01-8 10-methyl-(20RS... | CAS号3113-72-2 5-甲基-2-硝基苯甲酸 | CAS号608-05-9 5-甲基靛红 | CAS号16382-15-3 5-甲基吲哚-2-甲基酸酯

📜5-甲基-2-硝基苄醇置于silica Gel,戴斯-马丁氧化剂体系中,化学反应 0.03H,以85%的收率获得产物5-甲基-2-硝基苯甲醛
参考文献:二氧化硅上的戴斯-马丁高碘烷:使用微波快速氧化醇
标题:二氧化硅上的戴斯-马丁高碘烷:使用微波快速氧化醇
摘要:吸附在硅胶上.dess-Martin Periodinane 在无溶剂条件下暴露于微波后,可以将醇迅速氧化为相应的羰基化合物.
DOI:10.1080/10426500307797

专利信息

专利号:US-7608740-B2
优先权日:2005-08-03
标 题 :Method of synthesizing key intermediates for the production of camptothecin derivatives
发明人：RAO RAMAKRISHNA; RAO ALLA VENKATA RAMA
权利人:AVRA LAB PVT LTD
摘要:The present invention discloses a process for efficient production of 2-amino-5-hydroxypropiophenone corresponding to the AB ring part of camptothecin (CPT) skeleton, which is a key intermediate useful for the total synthesis of camptothecin analogs including 7-Ethyl-10-hydroxy camptothecin and novel intermediates thereof.

专利号:US-7378555-B2
优先权日:2001-02-21
标 题 :Method of synthesizing camptothecin-relating compounds
发明人：OGAWA TAKANORI; NISHIYAMA HIROYUKI; UCHIDA MIYUKI; SAWADA SEIGO
权利人:YAKULT HONSHA KK
摘要:The present invention is to prepare efficiently 2′-amino-5′-hydroxypropiophenone corresponding to the AB-ring part of camptothecin (CPT) skeleton and a tricyclic ketone corresponding to the CDE-ring part in order to provide efficiently CPT by the total synthesis, which is a starting material for irinotecan hydrochloride and various kinds of camptothecin derivatives, and to provide stably CPT and its derivatives.