CAS: 40972-16-5; 3-Hydrazinylpyridazine
该化合物是一种多用途的氢子ine衍生物,主要用作有机合成和制药研究的建筑块.它的活性氢子碱混合物对生产三环化合物,特别是以为基基的脚手架很有价值.盐的晶体可以增强稳定性和溶性,便于在水溶或极溶剂系统中处理.这种化合物经常用于生物活性分子的合成,包括针对...
- 英文名称3-Hydrazinylpyridazine
- 中文名称3-肼基哒嗪
- IUPAC名称3-hydrazineylpyridazine
- 其它别名3-Hydrazinopyridazine; 3-Hydrazinopyridazine Hydrochloride; 3-Hydrazinylpyridazine; Pyridazine, 3-Hydrazinyl-; 3-Pyridazinylhydrazine
- CAS编号40972-16-5
- MFCD编号:MFCD09258883
- 分子式:C4H6N4分子量:110.12
- 产品CID: 1424158
- 产品分类有机原料→分子砌块→芳杂环类化合物→哒嗪类化合物
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38956-79-5 5469-70-5 17284-97-8物理性质
MSDS等安全信息
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CAS号1120-95-2 3-氯哒嗪 | CAS号88491-61-6 3-溴哒嗪 | CAS号5469-70-5 3-氨基哒嗪 | CAS号69578-68-3 N-[(4,7,7-trime... | CAS号69578-84-3 ethyl (3E)-3-(p...合成工艺路线路线简述
📜3-溴哒嗪置于一水合肼体系中,用 正丁醇 作为反应溶剂,化学反应 4.0H,反应生成 3-肼基哒嗪盐酸盐
参考文献:Counotte-Potman,A.; Plas,H. C. Van Der,Journal Of Heterocyclic Chemistry,1983,Vol. 20,P. 1259-1261
标题:Counotte-Potman,A.; Plas,H. C. Van Der,Journal Of Heterocyclic Chemistry,1983,Vol. 20,P. 1259-1261
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合成参考文献
参考文献:10.1007/bf00543788
摘要:Karlberg BE, Larsson R, Ohman KP, Norlander B, Wirsen A, Hed J, Lundh BL, Flock A. Prizidilol, a combined vasodilatory and beta-adrenoceptor blocking drug, in primary hypertension. A long-term efficacy, tolerance and pharmacokinetic study. Eur J Clin Pharmacol. 1983;25(2):179–86. doi: 10.1007/bf00543788.
参考文献:10.1007/s13738-023-02901-y
摘要:Patil SS, Tadavi SK, Ghatole AM, Bendre RS. Transition metal complexes of pyridazine-based ligand: synthesis, characterization, biological activities, and molecular docking studies. J IRAN CHEM SOC. 2023 Oct 05;20(12):3103–17. doi: 10.1007/s13738-023-02901-y.
参考文献:10.1134/s1070363224050050
摘要:Gomktsyan TA, Karapetyan AV, Khachatryan AA, Avakyan DD, Hunanyan LS, Vorskanyan AS, Gharibyan YA, Gharibyan TK, Harutyunyan SV, Dovlatyan MV, Yengoyan AP, Ghazaryan EA. Sonochemical Green Synthesis and In Silico Study of Pyrazolylpyridazine-3-thione Derivatives. Russ J Gen Chem. 2024 May;94(5):1047–54. doi: 10.1134/s1070363224050050.
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