CAS: 2609-88-3; 2-(3,6-Bis(Diethylamino)Xanthylium-9-yl)-5-Sulfobenzenesulfonate

该化合物是一种属于Rhodami家族的荧光染色,广泛用于生物污点和荧光显微镜,其主要优点包括光度高,排放峰值在575纳米左右,适合需要红色荧光的应用,染色显示水溶性良好,通常与抗体,蛋白质或其他细胞成像标签和跟踪的生物分子相似,对光分解的阻力增强了活细胞研究的长期观测.此外,Lisamine rhodami B与普通激光线兼容,如532纳米波长,确保凝聚和超分辨率显微显微镜技术的多功能.

结构式图片

合成工艺路线路线简述

    📜Sulforhodamine B置于盐酸体系中,用 水 用作溶剂,化学反应 1.0H,反应生成磺酰罗丹明b
    参考文献:二苯并哌喃化合物,颜料组合物,彩色光阻剂,彩色滤光片及喷墨用印墨组合物
    标题:二苯并哌喃化合物,颜料组合物,彩色光阻剂,彩色滤光片及喷墨用印墨组合物
    摘要:本发明涉及二苯并哌喃化合物及含有该二苯并哌喃化合物的颜料组合物.提供一种于含有有机颜料的颜料组合物(颜料分散液)中,可在不会引起凝聚,沉降,随时间经过的粘度的增加下使有机颜料达到微粒化及高浓度化,且作为彩色滤光片用光阻剂或喷墨用印墨的着色剂的稳定的组合物(分散液).本发明的二苯并哌喃化合物具有以下述式(1)表示的结构:式(1)中,R1分别独立地表示氢原子或碳数1至4的烷基;R2及r3表示氢原子,碳数1至4的烷基,卤素原子,‑co2M基或‑so3M基;但r3的至少一个为‑co2M基或‑so3M基;M表示碱土金属原子或松香铵(8,11,13‑阿松香三烯‑18‑铵);N表示1至4的整数.

    海关参考信息

    专利信息


    专利号:US-2023235372-A1
    优先权日:2020-06-12
    标题:Ab-initio, template-independent synthesis of nucleic acids using thermostable enzymes
    发明人:RANDRIANJATOVO-GBALOU IRINA; SAID AHMED; RAHIER RENAUD
    权利人:SYNHELIX
    摘要:The invention relates to the field of nucleic acid synthesis or sequencing, more specifically to methods for ab-initio synthesis of nucleic acids, comprising contacting a nucleotide with a free 3′-hydroxyl group, with at least one nucleoside triphosphate, or a combination of nucleoside triphosphates, in the presence of an archaeal DNA primase or a functionally active fragment and/or variant thereof, thereby covalently binding said nucleoside triphosphate to the free 3′-hydroxyl group of the nucleotide. It also relates to isolated functionally active fragments of archaeal DNA primases which are capable of both ab-initio single-stranded nucleic acid synthesis activity and template-independent terminal nucleotidyl transferase activity.

    专利号:WO-2013057134-A1
    优先权日:2011-10-19
    标 题:Synthesis of semiconductor nanoparticles using metal precursors comprising non- or weakly coordinating anions
    发明人:BAHNMUELLER STEFAN; TIAN SUSAN; TIAN SHIZHE; HOHEISEL WERNER
    权利人:BAYER IP GMBH; BAYER SOUTH EAST ASIA PTE LTD
    摘要:The present invention relates to a method for the synthesis of semiconductor nanoparticles comprising elements of the groups IB, IIB, IIIA, IVA, VA or VIA of the periodic classification wherein the composition of the core nanoparticle is selected from the group consisting of IB-VIA, IIB-VIA, IIIA-VIA, IB-IIIA-VIA or IB-IIB-TVA-VIA, IIB-IIIA-VIA, IIB-TVA-VA or mixtures thereof, and at least one shell comprises elements of the groups IIB and VIA,, wherein in case the core composition is IIB-VIA the shell comprises at least a further element selected from the groups IB, IIIA, IVA or VA, using metal precursors comprising non- or weakly coordinating anions. It further relates to the consecutive process for the synthesis that includes first the preparation of a binary nanoparticle system then modified to make a ternary system which again can be further modified to make a quaternary system.

    专利号:US-2023235373-A1
    优先权日:2020-06-12
    标 题:Controlled template-independent synthesis of nucleic acids using thermostable enzymes
    发明人:RANDRIANJATOVO-GBALOU IRINA; SAID AHMED; RAHIER RENAUD
    权利人:SYNHELIX
    摘要:The invention relates to methods for template-independent synthesis of nucleic acids, comprising iteratively contacting an initiator sequence comprising a 3′-end nucleotide with a free 3′-hydroxyl group, with at least one nucleoside triphosphate, or a combination of nucleoside triphosphates, in the presence of an archaeal DNA primase or a functionally active fragment and/or variant thereof, thereby covalently binding said nucleoside triphosphate to the free 3-hydroxyl group of the 3-end nucleotide. It also relates to isolated functionally active fragments of archaeal DNA primases which are capable of template-independent terminal nucleotidyl transferase activity but are devoid of a template-independent primase activity.

    专利号:US-11447454-B2
    优先权日:2015-08-07
    标题:Synthesis of benzodiazepine derivatives
    发明人:BOYCE MALCOLM JAMES; THOMSEN LIV; GILBERT DONALD ALAN; WOOD DAVID
    权利人:TRIO MEDICINES LTD
    摘要:The invention relates to processes for the synthesis of benzodiazepine derivatives of Formula I:

    专利号:US-8853132-B2
    优先权日:2008-11-27
    标题 :Directed synthesis of oligophosphoramidate stereoisomers
    发明人:HEINDL DIETER; KESSLER DIRK; ROESLER ANGELIKA; SEIDEL CHRISTOPH; THUER WILMA
    权利人:ROCHE DIAGNOSTICS OPERATIONS
    摘要:The trivalent phosphorous atom of a compound is reacted with a reagent in such a manner that a stable phosphate mimetic or a specifier is formed. Phosphoramidites with a phosphorous atom containing at least one hydroxyl residue which is provided with a protective group are reacted for this purpose with a free hydroxyl group: In the first synthesis cycle the hydroxyl group is linked to a solid support via a cleavable or non-cleavable linker. In further synthesis cycles the hydroxyl group is created by cleavage of the protective group from the growing oligomer. This results in formation of a phosphorous acid triester which is reacted with azides. By selecting suitable monomers for the synthesis which have a defined stereoconformation compounds of Formula 1 are produced in a stereocontrolled manner.

    专利号:US-7541165-B2
    优先权日:2001-10-30
    标 题 :Molecular detection systems utilizing reiterative oligonucleotide synthesis
    发明人:HANNA MICHELLE M
    权利人:RIBOMED BIOTECHNOLOGIES INC
    摘要:The present invention provides methods for detecting the presence of a target molecule by generating multiple detectable oligonucleotides through reiterative enzymatic oligonucleotide synthesis events on a defined polynucleotide sequence. The methods generally comprise using a nucleoside, a mononucleotide, an oligonucleotide, or a polynucleotide, or analog thereof, to initiate synthesis of an oligonucleotide product that is substantially complementary to a target site on the defined polynucleotide sequence; optionally using nucleotides or nucleotide analogs as oligonucleotide chain elongators; using a chain terminator to terminate the polymerization reaction; and detecting multiple oligonucleotide products that have been synthesized by the polymerase. In one aspect, the invention provides a method for detecting a target protein, DNA or RNA by generating multiple detectable RNA oligoribonucleotides by abortive transcription.

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    ✅ COA系统入驻 | 共享模式

    主要参考文献


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    合成参考文献


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    参考文献:10.1007/s00280-005-0123-3
    摘要:Balin-Gauthier D, Delord JP, Rochaix P, Mallard V, Thomas F, Hennebelle I, Bugat R, Canal P, Allal C. In vivo and in vitro antitumor activity of oxaliplatin in combination with cetuximab in human colorectal tumor cell lines expressing different level of EGFR. Cancer Chemother Pharmacol. 2006 Jun;57(6):709–18. doi: 10.1007/s00280-005-0123-3.
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    摘要:Senawongse P, Pongprueksa P, Harnirattisai C, Sumi Y, Otsuki M, Shimada Y, Tagami J. Non-destructive assessment of cavity wall adaptation of class V composite restoration using swept-source optical coherence tomography. Dent Mater J. 2011;30(4):517–22. doi: 10.4012/dmj.2011-061.
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