CAS: 220996-80-5; 4-Bromo-2-(Trifluoromethoxy)Benzaldehyde

上下游产品

CAS号947583-96-2 4-溴-2-(三氟甲氧基)苯甲胺

📜4-溴-2-(三氟甲氧基)碘苯置于正丁基锂,水体系中,用 四氢呋喃,正己烷,Hexanes 用作溶剂,化学反应 6.0H,以78.6%的收率获得4-溴-2-(三氟甲氧基)苯甲醛
参考文献:Wo2007/98352
标题:Wo2007/98352

专利信息

专利号:WO-2010096722-A1
优先权日:2009-02-20
标 题 :3-oxo-2, 3-dihydro- [1,2, 4] triazolo [4, 3-a]pyridines as soluble epoxide hydrolase (seh) inhibitors
发明人：FENG JUN; KEUNG WALTER; NOTZ WOLFGANG REINHARD LUDWIG
权利人:TAKEDA PHARMACEUTICAL; FENG JUN; KEUNG WALTER; NOTZ WOLFGANG REINHARD LUDWIG
摘要:Claimed are intermediates in the synthesis of N-Arylmethyl-3-Oxo-2,3-dihydro- [1,2,4]triazolo[4,3-a]pyridine-6-carboxamides as well as a process (A) to arrive at 3-Oxo-2, 3-dihydro-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid. The triazolo[4,3-a]pyridine-6-carboxamides of formula (I) are used as soluble epoxide hydrolase inhibitors (sEH) having therapeutic effect in pathologic conditions such as hypertension, stroke, inflammatory processes, diabetes and a variety of cardiovascular diseases.

专利号:US-6090805-A
优先权日:1997-06-18
标 题 :Tocolytic oxytocin receptor antagonists
发明人：WILLIAMS PETER D; SPARKS MICHELLE A; BELL IAN; PERLOW DEBRA S; STAUFFER KENNETH; FREIDINGER ROGER M
权利人:MERCK & CO INC
摘要:This invention relates to certain novel benzoxazinone compounds and derivatives thereof, their synthesis, and their use as oxytocin receptor antagonists. One application of these compounds is in the treatment of preterm labor in mammals, especially humans. The ability of the compounds to relax uterine contractions in mammals also makes them useful for treating dysmenorrhea and stopping labor prior to cesarean delivery.

专利号:US-5968938-A
优先权日:1997-06-18
标 题 :Piperazine oxytocin receptor antagonists
发明人：WILLIAMS PETER D; SPARKS MICHELLE A; BELL IAN; GUARE JR JAMES P; FREIDINGER ROGER M
权利人:MERCK & CO INC
摘要:This invention relates to certain novel piperazine compounds and derivatives thereof, their synthesis, and their use as oxytocin receptor antagonists. One application of these compounds is in the treatment of preterm labor in mammals, especially humans. The ability of the compounds to relax uterine contractions in mammals also makes them useful for treating dysmenorrhea and stopping labor prior to cesarean delivery.