CAS: 220810-26-4; Histrelin Acetate

专利信息

专利号:US-8633204-B2
优先权日:2006-09-15
标 题 :4-methylpyridopyrimidinone compounds
发明人：CHENG HENGMIAO; BHUMRALKAR DILIP; DRESS KLAUS RUPRECHT; HOFFMAN JACQUI ELIZABETH; JOHNSON MARY CATHERINE; KANIA ROBERT STEVEN; LE PHUONG THI QUY; NAMBU MITCHELL DAVID; PAIRISH MASON ALAN; PLEWE MICHAEL BRUNO; TRAN KHANH TUAN
权利人:CHENG HENGMIAO; BHUMRALKAR DILIP; DRESS KLAUS RUPRECHT; HOFFMAN JACQUI ELIZABETH; JOHNSON MARY CATHERINE; KANIA ROBERT STEVEN; LE PHUONG THI QUY; NAMBU MITCHELL DAVID; PAIRISH MASON ALAN; PLEWE MICHAEL BRUNO; TRAN KHANH TUAN; PFIZER
摘要:The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), n nand to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-Kα).

专利号:US-11319320-B2
优先权日:2017-11-06
标题:PIM kinase inhibitor compositions, methods, and uses thereof
发明人：BURK MARK J; CHEN BRANDON; LI JINGYI; BACHAN SHAWN
权利人:SNAP BIO INC
摘要:This application relates to compounds of formulae (I) and (II) and compositions thereof useful as inhibitors of PIM kinases. Also provided are methods of synthesis and methods of use of PIM inhibitors in treating individuals suffering from cancerous malignancies.

专利号:US-8080556-B2
优先权日:2008-08-13
标 题 :2-amino pyrimidine compounds as potent HSP-90 inhibitors
发明人：KUNG PEI-PEI; MENG JERRY JIALUN
权利人:KUNG PEI-PEI; MENG JERRY JIALUN; PFIZER
摘要:The present invention is directed to compounds of formula (I), n nor pharmaceutically acceptable salts thereof, their synthesis, and their use as HSP-90 inhibitors.

专利号:FR-2956816-A1
优先权日:2010-03-01
标 题 :USE OF QUINOLONES FOR THE PREPARATION OF MEDICAMENTS, NEW QUINOLONES AND THEIR METHOD OF SYNTHESIS

专利号:EP-2118111-B1
优先权日:2007-02-06
标题 :2-amin0-5, 7-dihydr0-6h- pyrrolo [3, 4-d] pyrimidine derivatives as hsp-90 inhibitors for treating cancer
发明人：BENNETT MICHAEL JOHN; ZEHNDER LUKE RAYMOND; NINKOVIC SACHA; KUNG PEI-PEI; MENG JERRY JIALUN; HUANG BUWEN
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, their synthesis, and their use as HSP-90 inhibitors.