CAS: 20362-31-6; (3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(3-Methoxy-4-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Benzyl)Dihydrofuran-2(3H)-One

该化合物是一种自然产生的氟氯素化合物,与的植物分离,其主要优点包括强效抗氧化剂特性和抑制炎症途径的能力,有可能使其在需要防炎或皮肤舒缓活动的应用中有用.

结构式图片

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-11554133-B2
    优先权日:2017-03-16
    标题 :Bile acid synthesis promoter, composition for promoting bile acid synthesis and food composition for promoting bile acid synthesis
    发明人:WATANABE SHIMPEI; INAMASU SATOSHI; WATANABE MITSUHIRO; TAKASHINA Yoko
    权利人:KRACIE HOLDINGS LTD
    摘要:[Problem] To provide a novel medicine that is capable of promoting cholesterol metabolism to thereby treat, ameliorate or prevent various symptoms associated with increase in blood cholesterol level. [Solution] The present inventors newly found that arctigenin has an effect of promoting the conversion of cholesterol into bile acid. The present invention provides a bile acid synthesis promoter, a composition for promoting bile acid synthesis and a food composition for promoting bile acid synthesis each comprising arctigenin and/or arctiin as active ingredient(s).

    专利号:US-2007243147-A1
    优先权日:2004-07-24
    标 题:Skin and/or Hair Composition Containing Compounds for Increasing The Tanning of Skin
    发明人:WOLBER RAINER; TOM DIECK KAREN; SCHERNER CATHRIN; SCHLENZ KATHRIN; KRUSE INGE
    权利人:BEIERSDORF AG
    摘要:The invention relates to agents that are to be applied to the skin or hair and contain compounds for intensifying tanning of the skin and increasing melanin synthesis in skin or hair. The invention particularly relates to cosmetic or dermatological preparations. Using said preparations results in inducing and intensifying the tanning mechanisms of the skin, intensifying the hair color, and thus also increasing intrinsic protection of the skin or hair.

    专利号:WO-2024083930-A1
    优先权日:2022-10-18
    标 题:Topically applied preparation for improving skin condition
    发明人:HEUER ANDREA; HÜPEDEN JENNIFER
    权利人:BEIERSDORF AG
    摘要:The invention relates to a topically applied preparation comprising a combination of substances including antimicrobial peptides (AMP), in particular cyclic peptide compounds based on the synthesis of thiazolidine and oxazolidine components, and skin-soothing substances such as menthoxypropanediol, substances to strengthen the skin barrier such as omega-6 fatty acids, and/or flavonoids such as licochalcone, which act synergetically and selectively against pathogenic bacteria, such as S. aureus and C. acnes , however not against skin-commensal bacteria, such as S. epidermidis . The preparations can be used advantageously for the treatment of acne or atopic dermatitis and to care for skin that has been damaged by acne or atopic dermatitis.

    专利号:WO-2024083413-A1
    优先权日:2022-10-18
    标题:Topically applied preparation with antimicrobial peptides
    发明人:HEUER ANDREA; HÜPEDEN JENNIFER
    权利人:BEIERDSORF AG
    摘要:The invention relates to a topically applied preparation comprising a combination of substances including antimicrobial peptides (AMP), in particular cyclic peptide compounds based on the synthesis of thiazolidine and oxazolidine components, and skin-soothing substances such as menthoxypropanediol, substances to strengthen the skin barrier such as omega-6 fatty acids, and/or flavonoids such as licochalcone, which act synergetically and selectively against pathogenic bacteria, such as S. aureus and C. acnes, however not against skin-commensal bacteria, such as S. epidermidis. The preparations can be used advantageously for the treatment of acne or atopic dermatitis and to care for skin that has been damaged by acne or atopic dermatitis.

    专利号:WO-2023241290-A1
    优先权日:2022-06-13
    标 题:Pharmaceutical compound based on quinolizidine derivative, and preparation method therefor and use thereof
    发明人:YIN XIAOYING; WANG YANQING; LIU QINGSHAN; SHAN HONGLI; TANG LI; CHEN LINGYAN
    权利人:UNIV SHANGHAI ENG SCIENCE
    摘要:The present invention relates to the technical field of anti-tumor and anti-nerve-injury drug synthesis. Disclosed are an anti-tumor and anti-nerve-injury pharmaceutical compound based on a quinolizidine derivative, a use and a preparation method. Compared with the prior art, in the structural formula of the pharmaceutical compound provided by the present application, based on a natural quinolizidine alkaloid-isoflavone skeleton, structural modification is performed on an isoflavone part to obtain a series of derivatives, and experiments prove that the series of compounds can resist nerve injury, and has good application prospects in the aspect of preventing and treating nerve injury related diseases, wherein R2=R3=H; when R2 and R3 are functional groups which easily form a hydrogen bond, the series of compounds have anti-tumor activity and have application prospects. The present invention has the advantages that the preparation method is efficient and easy to operate, and the product has high purity and high activity.

    专利号:CN-219792511-U
    优先权日:2023-05-08
    标题:A kind of green ammonia synthesis system
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    主要参考文献


    1: Liu Y, Hou M, Pan Z, Tian X, Zhao Z, Liu T, Yang H, Shi Q, Chen X, Zhang Y, He F, Zhu X. Arctiin-reinforced antioxidant microcarrier antagonizes osteoarthritis progression. J Nanobiotechnology. 2022 Jun 27;20(1):303. doi: 10.1186/s12951-022-01505-7.
    2: Liu Z, Wu Y. Arctiin elevates osteogenic differentiation of MC3T3-E1 cells by modulating cyclin D1. Bioengineered. 2022 Apr;13(4):10866-10874. doi: 10.1080/21655979.2022.2066047.
    3: Lee CY, Hsin MC, Chen PN, Lin CW, Wang PH, Yang SF, Hsiao YH. Arctiin Inhibits Cervical Cancer Cell Migration and Invasion through Suppression of S100A4 Expression via PI3K/Akt Pathway. Pharmaceutics. 2022 Feb 5;14(2):365. doi: 10.3390/pharmaceutics14020365.

    合成参考文献


    参考文献:10.1186/1746-4269-7-21
    摘要:Lans C, Turner N. Organic parasite control for poultry and rabbits in British Columbia, Canada. Journal of Ethnobiology and Ethnomedicine. 2011 Jul 14;7(1):21. doi: 10.1186/1746-4269-7-21.
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