CAS: 18309-32-5; (1R,5R)-4,6,6-Trimethylbicyclo[3.1.1]Hept-3-En-2-One

该化合物是一种自然产生的单体质素酮,配有化学配方C10H14O.它的特征是,它具有令人愉快的,木质的和略微甜的芳香,在香味和口味行业中具有价值.它具有光学活性,展示了气质,这体现在它的名称是"(+)-Verbenone",表明它的具体对应形式.该物质通常来自各种基本油,特别是玫瑰和其他锥形油.除了其芳香特性外,还研究过它的潜在生物活动,包括杀虫和抗微生物效应.它还被用于制作用于虫害控制的球质,特别是在农业,它有助于管理某些昆虫群.该化合物被普遍认为在食品和化妆品应用中是安全的,但应当遵循管理准则.

结构式图片

相似化合物

1196-01-6 18881-04-4 80-57-9

上下游产品

马苄烯酮 Verbenone 80-57-9
(+)-Apoverbenone 35408-03-8
(+)-α-蒎烯 (+)-α-Pinene 7785-70-8
2-蒎烯聚合物 2,6,6-Trimethylbicyclo[3.1.1]Hept-2-Ene 25766-18-1
(-)-α-蒎烯 (-)-α-Pinene 7785-26-4

合成工艺路线路线简述

    2-蒎烯聚合物 以15%的收率获得
    参考文献:Retamar,J. A.,Essenze Deriv. Agrum.,59,(1989) N,C. 159-169
    标题:Retamar,J. A.,Essenze Deriv. Agrum.,59,(1989) N,C. 159-169

    海关参考信息

    专利信息


    专利号:US-5175378-A
    优先权日:1990-08-03
    标题 :Synthesis of optically pure forms of ipsdienol
    发明人:BROWN HERBERT C
    权利人:ALDRICH CHEM CO INC
    摘要:An improved process for preparing either optically pure enantiomer of the bark beetle pheromones ipsenol and ipsdienol is provided. The process is also applicable to the condensation of aldehydes of widely varying properties to the corresponding chiral alcohol.

    专利号:US-5175371-A
    优先权日:1990-08-03
    标 题:Synthesis of optically pure forms of ipsenol
    发明人:BROWN HERBERT C
    权利人:ALDRICH CHEM CO INC
    摘要:An improved process for preparing either optically pure enantiomer of the bark beetle pheromones ipsenol and ipsdienol is provided. The process is also applicable to the condensation of aldehydes of widely varying properties to the corresponding chiral alcohol.

    专利号:US-8257754-B2
    优先权日:2002-10-21
    标 题:Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response
    发明人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE M
    权利人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE M; METAPROTEOMICS LLC
    摘要:A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.

    专利号:US-8486457-B2
    优先权日:2002-10-21
    标 题:Compositions that treat or inhibit pathological conditions associated with inflammatory response
    发明人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE
    权利人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE; METAPROTEOMICS LLC
    摘要:A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.

    专利号:US-8557306-B2
    优先权日:2001-06-20
    标 题 :Compositions that treat or inhibit pathological conditions associated with inflammatory response
    发明人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE
    权利人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE; METAPROTEOMICS LLC
    摘要:A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.

    专利号:US-12076423-B2
    优先权日:2015-12-23
    标题 :Spiculisporic acid-based composition
    发明人:AGNAOU REDA; MARION CATHERINE
    权利人:OREAL
    摘要:Composition in the form of an oil-in-water emulsion that includes at least 1% of an oil phase, and an aqueous phase. The composition includes 0.1 to 15 wt % spiculisporic acid relative to the total weight of the composition, at least one base selected from amino acids and alkanolamines in an amount suitable for forming at least a monosalt of spiculisporic acid, less than 3% glycol(s) and/or polyol(s) relative to the total weight of the composition, at least one UV filter and/or an additive selected from volatile aromatic materials such as essential oils and fragrance substances, fillers, dyeing materials such as pigments, mother-of-pearl or particles with a metallic sheen, moisturizers, anti-wrinkle or anti-age agents, peeling agents, antioxidants, active ingredients stimulating the synthesis of epidermal and/or dermal macromolecules, dermo-relaxing agents, depigmentation agents, deodorant agents and mixtures thereof.
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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Takeda, T.; Tsubouchi, A., Science of Synthesis, (2009) 46, 69.
    摘要:Lam, K.; Leech, M. C.; Lennox, A. J. J., Science of Synthesis: Special Topics, (2021) 1, 442.
    参考文献:10.1021/jo0159082
    摘要:Moglioni AG, Muray E, Castillo JA, Alvarez-Larena A, Moltrasio GY, Branchadell V, Ortuño RM. Reaction between N-alkylhydroxylamines and chiral enoate esters: more experimental evidence for a cycloaddition-like process, a rationale based on DFT theoretical calculations, and stereoselective synthesis of new enantiopure beta-amino acids. J Org Chem. 2002 Apr 19;67(8):2402–10. doi: 10.1021/jo0159082.
    参考文献:10.1021/jf049913t
    摘要:Angioni A, Barra A, Cereti E, Barile D, Coïsson JD, Arlorio M, Dessi S, Coroneo V, Cabras P. chemical composition, plant genetic differences, antimicrobial and antifungal activity investigation of the essential oil of Rosmarinus officinalis L. J Agric Food Chem. 2004 Jun 02;52(11):3530–5. doi: 10.1021/jf049913t.
    参考文献:10.1007/s10886-014-0450-0
    摘要:Abdullah ZS, Ficken KJ, Greenfield BPJ, Butt TM. Innate Responses to Putative Ancestral Hosts: Is the Attraction of Western Flower Thrips to Pine Pollen a Result of Relict Olfactory Receptors Journal of Chemical Ecology. 2014 May 31;40(6):534–40. doi: 10.1007/s10886-014-0450-0.
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