CAS: 1345675-02-6; 2-Methyl-2-(4-(2-Oxo-9-(Quinolin-3-yl)-2H-[1,3]Oxazino[5,4-C]Quinolin-1(4H)-yl)Phenyl)Propanenitrile
- 英文名称2-Methyl-2-(4-(2-Oxo-9-(Quinolin-3-yl)-2H-[1,3]Oxazino[5,4-C]Quinolin-1(4H)-yl)Phenyl)Propanenitrile
- 中文名称α,α-二甲基-4-[2-氧代-9-(3-喹啉基)-2H-[1,3]恶嗪并[5,4-c]喹啉-1(4H)-基]-苯乙腈
- IUPAC名称2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2H-[1,3]oxazino[5,4-c]quinolin-1(4H)-yl)phenyl)propanenitrile
- 其它别名2-Methyl-2-[4-(2-Oxo-9-Quinolin-3-Yl-4H-[1,3]Oxazino[5,4-C]Quinolin-1-yl)Phenyl]Propanenitrile ; 4-[4-(1-Isocyano-1-Methyl-Ethyl)-Phenyl]-6-Quinolin-3-Yl-1,4-Dihydro-2-Oxa-4,9-Diaza-Phenanthren-3-One ; Atri
- CAS编号1345675-02-6
- MFCD编号:MFCD23160051
- 分子式:C30H22N4O2分子量:470.53
- 产品CID: 526756
- 产品分类Inhibitors/Agonists → PI3K/Akt/mTOR → PI3K | Inhibitors/Agonists → PI3K/Akt/mTOR → mTOR | Inhibitors/Agonists → DNA Damage → DNA-PK | Inhibitors/Agonists → DNA Damage → ATM/ATR
物理性质
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2912110000-甲醛
2915110000-甲酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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📌 第三方产品分析报告
主要参考文献
1: Beumer JH, Fu KY, Anyang BN, Siegfried JM, Bakkenist CJ. Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma. BMC Cancer. 2015 Oct 5;15:649. doi: 10.1186/s12885-015-1649-3.
2: Teng PN, Bateman NW, Darcy KM, Hamilton CA, Maxwell GL, Bakkenist CJ, Conrads TP. Pharmacologic inhibition of ATR and ATM offers clinically important distinctions to enhancing platinum or radiation response in ovarian, endometrial, and cervical cancer cells. Gynecol Oncol. 2015 Mar;136(3):554-61. doi: 10.1016/j.ygyno.2014.12.035.
3: Forero A, Giacobbi NS, McCormick KD, Gjoerup OV, Bakkenist CJ, Pipas JM, Sarkar SN. Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase. J Immunol. 2014 Jun 15;192(12):5933-42. doi: 10.4049/jimmunol.1303470.
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