CAS: 1014-81-9; 3-(Trifluoromethoxy)Benzoic Acid

相似化合物

148438-00-0 50823-90-0 52771-21-8

上下游产品

carbon dioxide 1-bromo-3-(trifluoromethoxy)benzene benzoic acid m-chloro-α,α,α-trifluoromethoxybenzene 2-nitro-5-(trifluoromethoxy)benzoic acid N-[4-methyl-3-(4-pyrazin-2-yl-pyrimidin-2-ylamino)-phenyl]-3-trifluoromethoxybenzamide N-[2-[(2-chloro-9-cyclopentyl-9H-purin-6-yl)-amino]-ethyl]-3-(trifluoromethoxy)-benzamide methyl 4-[(4-phenyl-3,6-dihydropyridin-1(2H)-yl)sulfonyl]methyl-1-[3-(trifluoromethoxy)benzoyl]piperidine-4-carboxylate

二氧化碳,3-三氟甲氧基溴苯置于锰,新铜试剂,Lithium Acetate,Cobalt(II) Bromide体系中,用 N,N-二甲基乙酰胺 用作溶剂,20.0 °C,101.33 Kpa 条件下,反应 12.0H,以85%的收率获得3-(三氟甲氧基)苯甲酸
参考文献:钴与钴的钴催化羧化芳基氯乙烯
标题:钴与钴的钴催化羧化芳基氯乙烯
摘要:很少研究用co 2过渡金属催化的芳基和氯乙烯的羧化,仅使用ni催化剂或钯与光氧化还原的混合物即可实现.在这项工作中,已经开发出了用co 2进行钴催化的芳基,氯乙烯和溴化物的羧化反应.这些转化在温和的条件下进行,并显示出较宽的底物范围,以高至高收率提供了相应的羧酸.
Doi:10.1039/d0Cc06451C

专利信息

专利号:US-7691843-B2
优先权日:2002-07-11
标 题 :N-hydroxyamide derivatives possessing antibacterial activity
发明人：RAJU BORE G; O'DOWD HARDWIN; GAO HONGWU; PATEL DINESH V; TRIAS JAOQUIM
权利人:PFIZER
摘要:Novel N-hydroxyamide derivatives are disclosed. These N-hydroxyamide derivatives inhibit UPD-3-O—(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase, an enzyme present in gram negative bacteria and are therefore useful as antimicrobials and antibiotics. Methods of synthesis and of use of the compounds are also disclosed.