CAS: 84483-28-3; 2-Chloro-6-Iodoaniline

该化合物是一种有机化合物,其特征是附在苯环上的氨基组(-NH2),该组同时具有氯原子和碘原子作为替代成分.氯位于2位置,而碘位于苯环的6位置,这表明一种影响其化学反应和特性的具体安排.该化合物一般在室内温度下是固体,在有机溶剂中表现出中等溶解性.其功能组表明有机合成中可能具有应用性,特别是在制药或农用化学物的开发中.卤素的存在也可增强它的再活动性,使其在各种化学反应中成为有用的中间体.此外,该化合物的结构可能会产生特定的物理特性,例如熔点和沸点,这些特性受到氢结合和van der Waals 相互作用等中间分子力量的影响.在处理该化合物时,应当注意安全防范,因为卤化的氨具有潜在的毒性.

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CAS号76838-82-9 2-chloro-6-phen...

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  • 6388-47-2 = 84483-28-3
    反应条件:1.1 Reagents: Iodine,Potassium Iodide,Oxygen Solvents: Acetonitrile; 8 H,180 °C
    标题:A Practical Route To 2-Iodoanilines Via The Transition-Metal-Free And Base-Free Decarboxylative Iodination Of Anthranilic Acids Under Oxygen
    作者:Rong,Nianxin; Et Al
    参考文献:Organic Chemistry Frontiers 日期:2021 卷标:8(16) 页码:4479-4484]

    937601-42-8 = 84483-28-3
    反应条件:1.1 Reagents: Hydrazine Hydrate (1:1) Catalysts: Palladium (On Carbon) Solvents: Methanol; 5 Min,Rt
    标题:Selective Reduction Of Halogenated Nitroarenes With Hydrazine Hydrate In The Presence Of Pd/c
    作者:Li,Fang; Et Al
    参考文献:Synlett 日期:2014 卷标:25(10) 页码:1403-1408
📜1-氯-2-碘-3-硝基苯置于5%-Palladium/activated Carbon,一水合肼体系中,用 甲醇 作为反应溶剂,化学反应 0.08H,反应生成 2-氯-6-碘苯胺,苯胺
参考文献:Selective Reduction Of Halogenated Nitroarenes With Hydrazine Hydrate In The Presence Of Pd/c
标题:Selective Reduction Of Halogenated Nitroarenes With Hydrazine Hydrate In The Presence Of Pd/c
摘要:A Large Variety Of Halogenated Nitroarenes Have Been Selectively Reduced With Hydrazine Hydrate In The Presence Of Pd/c To Give The Corresponding (Halogenated) Anilines In Good Yield.
DOI:10.1055/s-0033-1339025

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参考标题:A Pd-Catalyzed, Boron Ester-Mediated, Reductive Cross-Coupling Of Two Aryl Halides To Synthesize Tricyclic Biaryls
作者:Zhilong Chen,Xiaodong Wang
摘要:Tricyclic Biaryls Are Important Scaffold Structures In Many Natural Products And Lead Compounds In Drug Discovery. The Formation Of A Biaryl Unit Is Often The Key Step For The Synthesis Of Tricyclic Biaryls. Despite Significant Progress Toward The Synthesis Of Biaryl Compounds In Recent Years, The Direct Cross-Coupling Of Two Different Aryl Halides Is Still Challenging And Robust Methods Are Lacking

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摘要:Ghosh, B.; Maleczka, R. E., Jr., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 369.
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