CAS: 6921-34-2; Benzylmagnesium Chloride

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CAS号100-44-7 氯化苄 | CAS号100-39-0 溴化苄 | CAS号114272-48-9 (3-methyl-2-phe... | CAS号635-84-7 2-氯-4'-苯基苯乙酮 | CAS号60014-28-0 2-(dimethyl-l4-... | CAS号86901-19-1 MAGNESIUMANTHRA... | CAS号60-29-7 乙醚 | CAS号10131-46-1 6-benzyl-2-meth... | CAS号31406-67-4 四苄基铪 | CAS号55779-48-1 腔肠素 | CAS号375-22-4 七氟丁酸 | CAS号559-96-6 3,3,4,4,5,5,5-h... | CAS号81664-99-5 1,1,1,2,2,3,3-h... | CAS号3558-60-9 甲基苯乙基醚 | CAS号355803-76-8 1,2-Diphenyl-1-... | CAS号49568-78-7 2-苄基-3-氯喹噁啉

溴甲苯置于碘,Magnesium体系中,用 四氢呋喃 作为反应溶剂,化学反应 0.5H,反应生成 苄基氯化镁
参考文献:催化量的zn(II)盐存在下格氏试剂向硝基二烯的区域选择性1,4-共轭加成
标题:催化量的zn(II)盐存在下格氏试剂向硝基二烯的区域选择性1,4-共轭加成
摘要:在催化量的zn(II)盐存在下,格氏试剂可轻松地向硝基二烯进行区域选择性的1,4-共轭加成反应,且收率极高.转移了各种配体,例如烷基,芳基,杂芳基,烯丙基,乙烯基,1-炔基和烷氧基配体,而硫醇盐配体提供了1,6-区域选择性.反应在δ-烷基或芳基取代的α,β,γ,δ-二不饱和硝基二烯底物上成功进行.区域选择性受温度或溶剂选择的影响最小.
DOI:10.1021/ol500114M

专利信息

专利号:US-5703223-A
优先权日:1994-09-02
标题 :Solid phase synthesis of oligonucleotides with stereospecific substituted phosphonate linkages by pentavalent grignard coupling
发明人：WICKSTROM ERIC; LE BEC CHRISTINE
权利人:UNIV JEFFERSON
摘要:The present invention provides a method for producing an oligonucleotide having stereospecific substituted phosphonate linkages by use of a pentavalent Grignard coupling reaction on a solid phase support. The method can be used for automated synthesis of oligonucleotides having sequential equatorial or axial stereospecific substituted phosphonate linkages.

专利号:US-5880295-A
优先权日:1994-02-16
标 题 :Process for the preparation of diamine intermediates useful in the synthesis of HIV protease inhibitors
发明人：KALTENBACH III ROBERT FRANK
权利人:DU PONT PHARM CO
摘要:The present invention provides a process for the preparation of compounds of formula (V) below, and analogs thereof, which are useful as intermediates for the synthesis of HIV protease inhibitors, including cyclic ureas. ##STR1##

专利号:US-6271375-B1
优先权日:1997-06-30
标 题 :Ortho-metalation process for the synthesis of 2-substituted-1-(tetrazol-5-yl)benzenes
发明人：VILLA MARCO; ALLEGRINI PIETRO; ARRIGHI KATIUSCIA; PAIOCCHI MAURIZIO
权利人:ZAMBON SPA
摘要:A process of direct metalation of phenyltetrazoles useful for preparing compounds of formula (II) intermediates for the synthesis of angiotensin II antagonists is described.

专利号:US-6107495-A
优先权日:1996-07-24
标题:Thienylcyclohexane derivatives for thienylcyclohexyl synthesis
发明人：CAZAUX JEAN-BERNARD; DAFNIET MICHEL; KAMENKA JEAN-MARC; MANGINOT ERIC
权利人:EXPANSIA SA
摘要:PCT No. PCT/FR97/01382 Sec. 371 Date Jan. 19, 1999 Sec. 102(e) Date Jan. 19, 1999 PCT Filed Jul. 24, 1997 PCT Pub. No. WO98/03498 PCT Pub. Date Jan. 29, 1998Novel thienylcyclohexane derivatives of general formula (I), wherein R' is the 2-thienyl or 3-thienyl radical, R is the cyano radical or a radical of formula -C(O)A, and R2'' is a saturated or unsaturated optionally cyclic hydrocarbon radical, or an aryl radical, are disclosed. Methods for preparing said compounds, and the use thereof as novel industrial products for the synthesis of thienylcyclohexyl derivatives, are also disclosed.

专利号:US-5321143-A
优先权日:1988-05-26
标题 :Ruthenium-catalyzed production of cyclic sulfates
发明人：SHARPLESS K BARRY; GAO YUN
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:A ruthenium catalyzed method to synthesize cyclic sulfate compounds from the corresponding cyclic sulfites, and the cyclic sulfate reaction products obtained by this method. These cyclic sulfates further react with selected nucleophiles to give various substituted products. The method is an efficient means for the synthesis of chiral building blocks from tartaric acid enantiomers in high yields using an overall two-stage, one-pot reaction procedure. The chiral compounds can be transformed by nucleophilic reactions into chiral building blocks useful for the synthesis of natural biologically active products, such as antibiotics and pheromones.

专利号:US-8933181-B2
优先权日:2006-10-06
标题:Branched polymers and methods for their synthesis and use
发明人：MOURI HIROSHI; LUO STEVEN; KURASCH JESSICA; ROBERTSON CHRISTOPHER G; WARREN SANDRA
权利人:MOURI HIROSHI; LUO STEVEN; KURASCH JESSICA; ROBERTSON CHRISTOPHER G; WARREN SANDRA; BRIDGESTONE CORP
摘要:Branched polymers including multi-branched polymers, functionalized branched polymers, star-branched polymers, and dendigraft polymers. Methods for the synthesis of branched polymers and method for the use of branched polymers in tire components are also included.