CAS: 592-90-5; Hexamethyleneoxide

该化合物是一种循环醚,有七人环状结构,包括一个氧原子和六个碳原子;在室温下是一种无色液体,有典型的类似醚的气味;环内氧原子的存在有助于其化学反应,在一定条件下容易发生核生殖攻击和环开反应;氧环烷相对稳定,但可发生聚合或强酸或基底反应;水中的溶解性有限,但许多有机溶剂不易使用,因此在各种化学应用中有用;奥克西潘可作为有机合成的建筑块,可用于生产药品,农用化学品和其他精美化学品;安全数据表明,与许多环状醚一样,应对它应谨慎处理潜在的健康危害,包括对皮肤和呼吸系统产生刺激;建议采取适当的安全措施,包括使用个人防护设备,在与该化合物合作时采用.

结构式图片

相似化合物

62643-19-0 1505943-32-7 1369165-85-4

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号629-11-8 1,6-己二醇 | CAS号502-44-3 ε-己内酯 | CAS号86852-11-1 Diethyloxytriph... | CAS号2163-00-0 1,6-二氯己烷 | CAS号7664-93-9 硫酸 | CAS号2009-83-8 6-氯-1-己醇 | CAS号72037-38-8 oxepane-2-thione | CAS号4286-55-9 6-溴正己醇 | CAS号50592-87-5 1-溴-6-甲氧基己烷 | CAS号629-03-8 1,6-二溴己烷 | CAS号4286-55-9 6-溴正己醇 | CAS号40832-99-3 1-phenylazepane | CAS号14142-16-6 2-methyl-1-phen... | CAS号106-98-9 正丁烯 | CAS号50-00-0 甲醛 | CAS号109-67-1 1-戊烯 | CAS号75-07-0 乙醛 | CAS号74-86-2 乙炔 | CAS号106-97-8 丁烷 | CAS号2009-83-8 6-氯-1-己醇

合成工艺路线路线简述

    📜1,6-己二醇置于copper(Ll) Bromide体系中,用 四氢呋喃 作为反应溶剂,化学反应 12.0H,以99%的收率获得产物环氧己烷
    参考文献:铜催化剂存在下由二醇合成环醚
    标题:铜催化剂存在下由二醇合成环醚
    摘要:在铜的存在下,通过二醇的分子内脱水,以高收率合成了许多环醚,即四氢呋喃,2,5-二甲基四氢呋喃,四氢吡喃,1,4-二恶烷,氧杂环丁烷,氧杂环丁烷和1,4-氧杂蒽.基催化剂.
    DOI:10.1134/s1070428017120090

    海关参考信息

    专利信息


    专利号:US-12421534-B2
    优先权日:2021-11-10
    标 题 :Engineered enzymes and method for the synthesis of diverse tyrosine analogs
    发明人:ALMHJELL PATRICK J; ARNOLD FRANCES H
    权利人:CALIFORNIA INST OF TECHN
    摘要:Provided herein is an engineered tryptophan synthase β-subunit (TrpB) that catalyzes the synthesis of tyrosine, tyrosine analogs, or salts thereof. Also provided herein are methods for preparing tyrosine, tyrosine analogs, or a salt thereof using the engineered TrpB described herein.

    专利号:US-2004266827-A1
    优先权日:2003-06-25
    标 题 :Convergent asymmetric route to produce a key intermediate towards the synthesis of a garft inhibitor
    发明人:NOTZ WOLFGANG REINHARD LUDWIG; MARTINEZ CARLOS ALBERTO
    权利人:AGOURON PHARMA
    摘要:The invention relates to processes for the preparation of a key intermediate in the synthesis of a GARFT inhibitor of formula (Ia) containing a 4-methyl-substituted thiophene core: n n n wherein said key intermediate has the following formula (I): n n n wherein each of R 1 and R 2 are independently a moiety that together with the attached CO 2 forms a readily hydrolyzable ester group; n from a compound of the formula (VI): n n n wherein R 1 is as described above, Pg 1 is an amino protecting group, and Pg 2 is an ether protecting group; wherein said processes are as described in the specification.

    专利号:US-11858953-B2
    优先权日:2018-04-04
    标 题:Compositions and methods for synthesis of phosphorylated molecules
    发明人:CHAPUT JOHN; LIAO JEN-YU; BALA SAIKAT
    权利人:UNIV CALIFORNIA
    摘要:The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.

    专利号:US-2006183758-A1
    优先权日:2005-02-17
    标 题:Method for synthesis of AZA-annelated pyrroles, thiophenes, and furans
    发明人:BEARD CHARLES D; LEE VING J; WHITTLE C E
    权利人:CB RES AND DEV INC
    摘要:Methods of synthesis of intermediates that are useful as bioisosteres of the indole, benzofuran and benzothiophene scaffold are disclosed.

    专利号:US-4239689-A
    优先权日:1978-12-18
    标题 :Total synthesis of the utero-evacuant substance d,l-zoapatanol
    发明人:KANE VINAYAK V
    权利人:ORTHO PHARMA CORP
    摘要:A method for the synthesis of racemic 2S*, 3R*-6E-(2'-hydroxyethylidene)-2-methyl-2-(4',8'-dimethyl-5'-oxo-7'-nonenyl)-oxepan-3-ol is described. The naturally occurring product, 2S, 3R-6E-(2'-hydroxyethylidene)-2-methyl-2-(4',8'-dimethyl-5'-oxo-7'-nonenyl)-oxepan-3-ol, is one of the active components of the zoapatle plant.

    专利号:US-4237053-A
    优先权日:1978-12-20
    标 题 :Total synthesis of the utero-evacuant substance d,l-zoapatanol
    发明人:KANE VINAYAK V
    权利人:ORTHO PHARMA CORP
    摘要:A method for the synthesis of racemic 2S*,3R*-6E-(2'-hydroxyethylidene)-2-methyl-2-(4',8'-dimethyl-5'-oxo-7'-nonenyl)-oxepan-3-ol is described. The naturally occurring product, 2S,3R-6E-(2'-hydroxyethylidene)-2-methyl-2-(4',8'-dimethyl-5'-oxo-7'-nonenyl)-oxepan-3-ol, is one of the active components of the zoapatle plant.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:André-Joyaux, E.; Gnägi, L.; Meléndez, C.; Soulard, V.; Renaud, P., Science of Synthesis, (2021) , 461.
    摘要:E. M. Arnett and C. Y. Wu. J. Am. Chem Soc. 84, 1684 (1962).
    摘要:Das, A.; Sarmah, B. K., Science of Synthesis: Knowledge Updates, (2024) 1, 315.
    摘要:Li, X.; Song, Q., Science of Synthesis: Cross-Dehydrogenative Coupling, (2023) nan, 341.
    摘要:Faisca Phillips, A. M.; Guedes da Silva, M. F. C.; Pombeiro, A. J. L., Science of Synthesis: Cross-Dehydrogenative Coupling, (2023) nan, 557.
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