CAS: 590-00-1; Potassium Hexa-2,4-Dienoate

专利信息

专利号:WO-2024222981-A1
优先权日:2023-04-28
标题 :Ester conjugate of sphingolipid and hyaluronan, method of synthesis thereof, composition containing thereof, use of conjugate or composition
发明人：JUHASCIK MARTIN; HUERTA-ANGELES GLORIA; STARMANOVA KATERINA; STEPAN PETR; EXNEROVA ANDREA; NESPOROVA KRISTINA; KOVACIK ANDREJ; BRANDEJSOVA MARTINA; VECEROVA PETRA; POLASKOVA JANA; HERMANNOVA MARTINA; BUFFA RADOVAN; VAGNEROVA HANA; VELEBNY VLADIMIR
权利人:CONTIPRO AS
摘要:The present invention relates to an ester conjugate of sphingolipid and hyaluronan, a composition comprising thereof and its use. Furthermore, it relates to methods of the ester conjugate synthesis.

专利号:US-2020054045-A1
优先权日:2008-09-03
标 题 :All-Natural Drink Composition for Synthesizing and Regenerating Adenosine Triphosphate (ATP) in Muscle Cells and Neurons, Repairing Exercise-Induced Muscle Fiber Damage, Repletion of Glycogen Stores in the Muscle and Liver, Enhancing Blood Flow to Tissue during Intense Exercise, and Preventing and Reducing Oxidative Damage to Tissues during Exercise with Minimal Gastrointestinal Disturbances
发明人：SCHMIDT MICHAEL JAMES; AVARBOCK DAVID
权利人:BIOMECHANICAL TECH LLC
摘要:The present invention provides for a nutritional composition in a liquid drink form, dry powder form, gel form, or carrier form intended to optimize human physiological performance during intense exercise and subsequently return the body to its healthy, pre-exercise state. The composition comprises a carbohydrate and a protein, and preferably a ratio of the carbohydrate to the protein is greater than about 4.3 parts by weight carbohydrate to 1 part by weight protein. Preferably, the liquid nutritional composition is comprised of: (1) carbohydrate in the range of 3.45-10% by weight of the liquid nutritional composition to allow immediate and long-term energy production by muscle cells and neurons, insulin modulation, and muscle glycogen sparing, the carbohydrate being in the form of monosaccharides or polysaccharides or a combination thereof, and the saccharides preferably comprising 40-95% dextrose by weight of the final volume of saccharides, 5-45% fructose by weight of the final volume of saccharides, and 1-25% glucose polymer by weight of the final volume of saccharides; (2) a protein source that contains all 20 “standardâ€? amino acids, in the range of 0.1-0.8% by weight of the liquid nutritional composition, whose inherent structure plus further chemical modification results in amino acid absorption into the bloodstream rapid enough for initiating and enhancing protein synthesis and subsequent muscle cell repair during the exercise and post-exercise periods; (3) Branched-Chain Amino Acids (BCAA), leucine, isoleucine, valine, for use by muscle cells for energy thus sparing glycogen stores, for increasing protein synthesis by stimulating insulin and growth hormone release, and for reducing protein degradation; (4) precursors of the signaling molecule nitric oxide, important for increasing blood flow and subsequent nutrient delivery (including those in this composition) to tissue during intense exercise; (5) precursors of creatine, a molecule important for ATP regeneration in muscle and nerve cells and for muscle cell volumizing effects; (6) a mixture of hydrophilic and hydrophobic antioxidants: retinol/Beta-carotene (Vitamin A), ascorbic acid (Vitamin C), and di-alpha-tocopheryl acetate (Vitamin E); ubiquinone (coenzyme Q 10 [5-100 mg/500 ml], which in addition to its antioxidant properties is also important for ATP generation and Vitamin E regeneration; a mixture of 10-100 mg epigallocatechin gallate (EGCG) and 25-150 mg polyphenols from green tea extract; 40-250 mg ellagic acid and punicalagin from pomegranate or raspberry extract, at ratios comparable to that found in the whole fruit, which have been shown to have protective effects on blood vessels as well as inhibiting stimulation of the pro-inflammatory protein interleukin-1 b (IL-b) which causes degradation and damage to joints (These six antioxidants prevent and eradicate reactive oxygen species and free radicals generated during strenuous exercise, thus preserving muscle integrity.); and (7) the ions Na+, Cl−, K+, Ca+2, Mg+ 2 , and Zn+ 2 , which are important for the muscle fiber contraction and relaxation cycle, for neuronal signal propagation, for repletion of such ions lost in excessive perspiration during exercise, for water absorption in the gastrointestinal tract, and for catalytic action by energy producing and antioxidant enzymes.

专利号:US-9849083-B2
优先权日:2011-12-14
标题 :Sublingual administration of statins
发明人：SAMS MARTIN JAMES; HIGH JULIET VICTORIA; JAMIESON PAUL ANDREW; BOOLES CLIVE
权利人:LONDONPHARMA LTD
摘要:The invention provides a pharmaceutical composition for the transmucosal delivery of a statin, said composition comprising a statin and a carrier in which said statin is soluble or forms a suspension or emulsion. The invention also provides a pharmaceutical composition comprising a statin for use in inhibiting cholesterol synthesis in vivo, where in said use said composition is delivered by the transmucosal route.

专利号:US-6051236-A
优先权日:1998-11-12
标题 :Composition for optimizing muscle performance during exercise
发明人：PORTMAN ROBERT
权利人:PACIFICHEALTH LAB INC
摘要:A nutritional composition in a dry powder form for optimizing muscle performance during exercise and for enhancing muscle cell repair and recovery following the cessation of exercise. The dry nutritional composition includes carbohydrates and proteins in a ratio in the range of 2.8 to 4.2 parts of the carbohydrates to 1.0 part of the proteins, wherein the carbohydrates are used for providing energy during exercise and the proteins are used for stimulating the release of insulin to the muscle cells during exercise and for repairing muscle cells after exercise. The dry nutritional composition further includes glutamine for reducing muscle stress by stimulating the immune system and for stimulating muscle cell recovery after exercise; arginine for stimulating the release of insulin within the muscle cells in order to facilitate the transport of glucose into the muscle cells during exercise and for the synthesis of glucose into glycogen; vitamin C for use as an anti-oxidant for preventing free radical formation during exercise and for protecting muscle cell integrity during exercise; and vitamin E for use as an anti-oxidant for preventing free radical formation during exercise and for protecting muscle cell integrity during exercise. Additionally, the dry nutritional composition also includes one or more electrolytes for replenishing electrolytes lost during exercise and for facilitating intestinal reabsorption of fluids, and for facilitating energy dependent processes; and an herbal compound being ciwujia for enhancing the immune system, reducing muscle stress, and decreasing heart rate during exercise.

专利号:WO-2020226482-A1
优先权日:2019-05-09
标题:Synergistic compositions for controlling plant pathogens with chitinolytic microorganisms / organic acid combinations and method of use thereof
发明人：LAI HONG HENG
权利人:LAI HONG HENG
摘要:The present invention relates to pesticidal compositions and methods for controlling plant pathogens, particularly basal stem rot in the oil palm primarily caused by Ganoderma species. The pesticidal compositions comprising, as active components: (A) Bioactive compound derived from a whole broth culture of an chitinolyic microorganisms, wherein the bioactive compound comprises any or any combination of: chitinolyic microorganism, whole cell broths, liquid cultures, spores, pure cultures, cell fraction, substances, suspensions, supernatants, filtrates, extract or a cell-free extract thereof or metabolite thereof or isolated compounds, wherein the bioactive compound is derived from at least one chitinolyic microorganisms that degrade chitinous substrates. The said chitinolytic microorganism is bacteria belonging to genus Bacillus, Streptomyces and/or fungal genus Trichoderma; (B) at least one organic acid; and (C) at least one pesticide selected from chemical pesticides, microbial pesticides, plant defense activators, cuticle degrading enzymes, cell wall synthesis inhibitors, bacteriocins, antifungal peptides, antimicrobial preservatives, plant oil or plant extract. More specifically, this invention envisions the use of bioactive compounds and/or metabolites from chitinolyic microorganisms in combination essentially of organic acid and the compositions comprising them, in the use form as fungicides and/or insecticides, also be present as 'booster' to other pesticides results in many cases in an expension of pesticidal spectrum of activity or in a prevention of pesticide resistance development. Furthermore, in many cases, synergistic effects are obtained. In various embodiments, the organic acid consists essentially of acetic acid, preferably acetic acid from a fermentation. The formulation is typically applied to agricultural soil or plant material. In a particular, the present invention can be used in combination with a carrier selected from the plant growth nutrient, organic fertilizer or inorganic/organic mixture fertilizer. Although the following description relates almost exclusively to managing basal stem rot (BSR) disease in oil palm primarily caused by Gonoderma species. It will be appreciated by those skill in the art that the invention could be used to treat other diseases and pests of other plants, includes but is not limited to a fungus, bacteria, actinomycete, virus, insects, Acari and/or nematodes.

专利号:US-5096710-A
优先权日:1989-05-27
标 题 :Poison bait for control of noxious insects
发明人：MINAGAWA FUMIYASU; KOHAMA TAKUJI; KAWADA HITOSHI; SHINJO GORO; MAEDA KAZUYUKI
权利人:SUMITOMO CHEMICAL CO
摘要:A bait composition in a tablet form, which comprises as the essential components (a) at least one insect-growth controlling agent chosen from (a-1) insect juvenile hormone-like compounds and (a-2) insect chitin-synthesis inhibitors, (b) dextrin and (c) a plant oil in an amount of not more than 10% by weight to the total bait composition.